TopFIND 4.0

Q9H1K1: Iron-sulfur cluster assembly enzyme ISCU, mitochondrial

General Information

Protein names
- Iron-sulfur cluster assembly enzyme ISCU, mitochondrial
- NifU-like N-terminal domain-containing protein
- NifU-like protein
Gene names ISCU
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q9H1K1

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAAAGAFRLR RAASALLLRS PRLPARELSA PARLYHKKVV DHYENPRNVG SLDKTSKNVG 
        70         80         90        100        110        120 
TGLVGAPACG DVMKLQIQVD EKGKIVDARF KTFGCGSAIA SSSLATEWVK GKTVEEALTI 
       130        140        150        160    
KNTDIAKELC LPPVKLHCSM LAEDAIKAAL ADYKLKQEPK KGEAEKK

Isoforms

- Isoform 2 of Iron-sulfur cluster assembly enzyme ISCU, mitochondrial

Sequence View

        10         20         30         40         50         60 
MAAAGAFRLR RAASALLLRS PRLPARELSA PARLYHKKVV DHYENPRNVG SLDKTSKNVG 
        70         80         90        100        110        120 
TGLVGAPACG DVMKLQIQVD EKGKIVDARF KTFGCGSAIA SSSLATEWVK GKTVEEALTI 
       130        140        150        160    
KNTDIAKELC LPPVKLHCSM LAEDAIKAAL ADYKLKQEPK KGEAEKK



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Protease Assignment Confidence:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9H1K1-35-unknown YHKKVV... 35 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9H1K1-38- KVVDHY... 38 Subtiligase Based Positive Selection Wells apoptotic_RPMI_Dox 23264352

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...EAEKK 167 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...EAEKK 167 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt73712

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)