TopFIND 4.0

Q9H227: Cytosolic beta-glucosidase {ECO:0000305|PubMed:11389701}

General Information

Protein names
- Cytosolic beta-glucosidase {ECO:0000305|PubMed:11389701}
- 3.2.1.21 {ECO:0000269|PubMed:11389701, ECO:0000269|PubMed:11784319, ECO:0000269|PubMed:20728381}
- Cytosolic beta-glucosidase-like protein 1
- Cytosolic glycosylceramidase {ECO:0000303|PubMed:17595169}
- Cytosolic GCase {ECO:0000303|PubMed:17595169}
- Glucosidase beta acid 3 {ECO:0000312|HGNC:HGNC:19069}
- Glucosylceramidase beta 3 {ECO:0000312|HGNC:HGNC:19069}
- Klotho-related protein {ECO:0000303|PubMed:17595169}
- KLrP {ECO:0000303|PubMed:17595169}
Gene names GBA3
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q9H227

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAFPAGFGWA AATAAYQVEG GWDADGKGPC VWDTFTHQGG ERVFKNQTGD VACGSYTLWE 
        70         80         90        100        110        120 
EDLKCIKQLG LTHYRFSLSW SRLLPDGTTG FINQKGIDYY NKIIDDLLKN GVTPIVTLYH 
       130        140        150        160        170        180 
FDLPQTLEDQ GGWLSEAIIE SFDKYAQFCF STFGDRVKQW ITINEANVLS VMSYDLGMFP 
       190        200        210        220        230        240 
PGIPHFGTGG YQAAHNLIKA HARSWHSYDS LFRKKQKGMV SLSLFAVWLE PADPNSVSDQ 
       250        260        270        280        290        300 
EAAKRAITFH LDLFAKPIFI DGDYPEVVKS QIASMSQKQG YPSSRLPEFT EEEKKMIKGT 
       310        320        330        340        350        360 
ADFFAVQYYT TRLIKYQENK KGELGILQDA EIEFFPDPSW KNVDWIYVVP WGVCKLLKYI 
       370        380        390        400        410        420 
KDTYNNPVIY ITENGFPQSD PAPLDDTQRW EYFRQTFQEL FKAIQLDKVN LQVYCAWSLL 
       430        440        450        460    
DNFEWNQGYS SRFGLFHVDF EDPARPRVPY TSAKEYAKII RNNGLEAHL

Isoforms

- Isoform 2 of Cytosolic beta-glucosidase

Sequence View

        10         20         30         40         50         60 
MAFPAGFGWA AATAAYQVEG GWDADGKGPC VWDTFTHQGG ERVFKNQTGD VACGSYTLWE 
        70         80         90        100        110        120 
EDLKCIKQLG LTHYRFSLSW SRLLPDGTTG FINQKGIDYY NKIIDDLLKN GVTPIVTLYH 
       130        140        150        160        170        180 
FDLPQTLEDQ GGWLSEAIIE SFDKYAQFCF STFGDRVKQW ITINEANVLS VMSYDLGMFP 
       190        200        210        220        230        240 
PGIPHFGTGG YQAAHNLIKA HARSWHSYDS LFRKKQKGMV SLSLFAVWLE PADPNSVSDQ 
       250        260        270        280        290        300 
EAAKRAITFH LDLFAKPIFI DGDYPEVVKS QIASMSQKQG YPSSRLPEFT EEEKKMIKGT 
       310        320        330        340        350        360 
ADFFAVQYYT TRLIKYQENK KGELGILQDA EIEFFPDPSW KNVDWIYVVP WGVCKLLKYI 
       370        380        390        400        410        420 
KDTYNNPVIY ITENGFPQSD PAPLDDTQRW EYFRQTFQEL FKAIQLDKVN LQVYCAWSLL 
       430        440        450        460    
DNFEWNQGYS SRFGLFHVDF EDPARPRVPY TSAKEYAKII RNNGLEAHL



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


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Biological System:


Protease Assignment Confidence:


Evidence Names:


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Lab:



Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9H227-1-unknown MAFPAG... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9H227-1-unknown MAFPAG... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt75752

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...LEAHL 469 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...LEAHL 469 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt71370

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)