TopFIND 4.0

Q9H2S1: Small conductance calcium-activated potassium channel protein 2

General Information

Protein names
- Small conductance calcium-activated potassium channel protein 2
- SK2
- SKCa 2
- SKCa2
- KCa2.2
Gene names KCNN2
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q9H2S1

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSSCRYNGGV MRPLSNLSAS RRNLHEMDSE AQPLQPPASV GGGGGASSPS AAAAAAAAVS 
        70         80         90        100        110        120 
SSAPEIVVSK PEHNNSNNLA LYGTGGGGST GGGGGGGGSG HGSSSGTKSS KKKNQNIGYK 
       130        140        150        160        170        180 
LGHRRALFEK RKRLSDYALI FGMFGIVVMV IETELSWGAY DKASLYSLAL KCLISLSTII 
       190        200        210        220        230        240 
LLGLIIVYHA REIQLFMVDN GADDWRIAMT YERIFFICLE ILVCAIHPIP GNYTFTWTAR 
       250        260        270        280        290        300 
LAFSYAPSTT TADVDIILSI PMFLRLYLIA RVMLLHSKLF TDASSRSIGA LNKINFNTRF 
       310        320        330        340        350        360 
VMKTLMTICP GTVLLVFSIS LWIIAAWTVR ACERYHDQQD VTSNFLGAMW LISITFLSIG 
       370        380        390        400        410        420 
YGDMVPNTYC GKGVCLLTGI MGAGCTALVV AVVARKLELT KAEKHVHNFM MDTQLTKRVK 
       430        440        450        460        470        480 
NAAANVLRET WLIYKNTKLV KKIDHAKVRK HQRKFLQAIH QLRSVKMEQR KLNDQANTLV 
       490        500        510        520        530        540 
DLAKTQNIMY DMISDLNERS EDFEKRIVTL ETKLETLIGS IHALPGLISQ TIRQQQRDFI 
       550        560        570    
EAQMESYDKH VTYNAERSRS SSRRRRSSST APPTSSESS

Isoforms

- Isoform 2 of Small conductance calcium-activated potassium channel protein 2

Sequence View

        10         20         30         40         50         60 
MSSCRYNGGV MRPLSNLSAS RRNLHEMDSE AQPLQPPASV GGGGGASSPS AAAAAAAAVS 
        70         80         90        100        110        120 
SSAPEIVVSK PEHNNSNNLA LYGTGGGGST GGGGGGGGSG HGSSSGTKSS KKKNQNIGYK 
       130        140        150        160        170        180 
LGHRRALFEK RKRLSDYALI FGMFGIVVMV IETELSWGAY DKASLYSLAL KCLISLSTII 
       190        200        210        220        230        240 
LLGLIIVYHA REIQLFMVDN GADDWRIAMT YERIFFICLE ILVCAIHPIP GNYTFTWTAR 
       250        260        270        280        290        300 
LAFSYAPSTT TADVDIILSI PMFLRLYLIA RVMLLHSKLF TDASSRSIGA LNKINFNTRF 
       310        320        330        340        350        360 
VMKTLMTICP GTVLLVFSIS LWIIAAWTVR ACERYHDQQD VTSNFLGAMW LISITFLSIG 
       370        380        390        400        410        420 
YGDMVPNTYC GKGVCLLTGI MGAGCTALVV AVVARKLELT KAEKHVHNFM MDTQLTKRVK 
       430        440        450        460        470        480 
NAAANVLRET WLIYKNTKLV KKIDHAKVRK HQRKFLQAIH QLRSVKMEQR KLNDQANTLV 
       490        500        510        520        530        540 
DLAKTQNIMY DMISDLNERS EDFEKRIVTL ETKLETLIGS IHALPGLISQ TIRQQQRDFI 
       550        560        570    
EAQMESYDKH VTYNAERSRS SSRRRRSSST APPTSSESS



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Evidence Names:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9H2S1-1-unknown MSSCRY... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9H2S1-349-unknown MWLISI... 349 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt78795

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...SSESS 579 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...SSESS 579 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt74413

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)