Q9H3H1: tRNA dimethylallyltransferase

General Information

Protein names	- tRNA dimethylallyltransferase - 2.5.1.75 {ECO:0000269\|PubMed:24901367} - Isopentenyl-diphosphate:tRNA isopentenyltransferase - IPP transferase - IPPT - hGRO1 - tRNA isopentenyltransferase 1 - IPTase
Gene names	TRIT1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9H3H1

5 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of tRNA dimethylallyltransferase, mitochondrial - Isoform 3 of tRNA dimethylallyltransferase, mitochondrial - Isoform 4 of tRNA dimethylallyltransferase, mitochondrial - Isoform 5 of tRNA dimethylallyltransferase, mitochondrial - Isoform 6 of tRNA dimethylallyltransferase, mitochondrial - Isoform 2 of tRNA dimethylallyltransferase - Isoform 3 of tRNA dimethylallyltransferase - Isoform 4 of tRNA dimethylallyltransferase - Isoform 5 of tRNA dimethylallyltransferase - Isoform 6 of tRNA dimethylallyltransferase

Sequence View

        10         20         30         40         50         60
MASVAAARAV PVGSGLRGLQ RTLPLVVILG ATGTGKSTLA LQLGQRLGGE IVSADSMQVY
        70         80         90        100        110        120
EGLDIITNKV SAQEQRICRH HMISFVDPLV TNYTVVDFRN RATALIEDIF ARDKIPIVVG
       130        140        150        160        170        180
GTNYYIESLL WKVLVNTKPQ EMGTEKVIDR KVELEKEDGL VLHKRLSQVD PEMAAKLHPH
       190        200        210        220        230        240
DKRKVARSLQ VFEETGISHS EFLHRQHTEE GGGPLGGPLK FSNPCILWLH ADQAVLDERL
       250        260        270        280        290        300
DKRVDDMLAA GLLEELRDFH RRYNQKNVSE NSQDYQHGIF QSIGFKEFHE YLITEGKCTL
       310        320        330        340        350        360
ETSNQLLKKG IEALKQVTKR YARKQNRWVK NRFLSRPGPI VPPVYGLEVS DVSKWEESVL
       370        380        390        400        410        420
EPALEIVQSF IQGHKPTATP IKMPYNEAEN KRSYHLCDLC DRIIIGDREW AAHIKSKSHL
       430        440        450        460
NQLKKRRRLD SDAVNTIESQ SVSPDHNKEP KEKGSPGQND QELKCSV         10         20         30         40         50         60
MASVAAARAV PVGSGLRGLQ RTLPLVVILG ATGTGKSTLA LQLGQRLGGE IVSADSMQVY
        70         80         90        100        110        120
EGLDIITNKV SAQEQRICRH HMISFVDPLV TNYTVVDFRN RATALIEDIF ARDKIPIVVG
       130        140        150        160        170        180
GTNYYIESLL WKVLVNTKPQ EMGTEKVIDR KVELEKEDGL VLHKRLSQVD PEMAAKLHPH
       190        200        210        220        230        240
DKRKVARSLQ VFEETGISHS EFLHRQHTEE GGGPLGGPLK FSNPCILWLH ADQAVLDERL
       250        260        270        280        290        300
DKRVDDMLAA GLLEELRDFH RRYNQKNVSE NSQDYQHGIF QSIGFKEFHE YLITEGKCTL
       310        320        330        340        350        360
ETSNQLLKKG IEALKQVTKR YARKQNRWVK NRFLSRPGPI VPPVYGLEVS DVSKWEESVL
       370        380        390        400        410        420
EPALEIVQSF IQGHKPTATP IKMPYNEAEN KRSYHLCDLC DRIIIGDREW AAHIKSKSHL
       430        440        450        460
NQLKKRRRLD SDAVNTIESQ SVSPDHNKEP KEKGSPGQND QELKCSV         10         20         30         40         50         60
MASVAAARAV PVGSGLRGLQ RTLPLVVILG ATGTGKSTLA LQLGQRLGGE IVSADSMQVY
        70         80         90        100        110        120
EGLDIITNKV SAQEQRICRH HMISFVDPLV TNYTVVDFRN RATALIEDIF ARDKIPIVVG
       130        140        150        160        170        180
GTNYYIESLL WKVLVNTKPQ EMGTEKVIDR KVELEKEDGL VLHKRLSQVD PEMAAKLHPH
       190        200        210        220        230        240
DKRKVARSLQ VFEETGISHS EFLHRQHTEE GGGPLGGPLK FSNPCILWLH ADQAVLDERL
       250        260        270        280        290        300
DKRVDDMLAA GLLEELRDFH RRYNQKNVSE NSQDYQHGIF QSIGFKEFHE YLITEGKCTL
       310        320        330        340        350        360
ETSNQLLKKG IEALKQVTKR YARKQNRWVK NRFLSRPGPI VPPVYGLEVS DVSKWEESVL
       370        380        390        400        410        420
EPALEIVQSF IQGHKPTATP IKMPYNEAEN KRSYHLCDLC DRIIIGDREW AAHIKSKSHL
       430        440        450        460
NQLKKRRRLD SDAVNTIESQ SVSPDHNKEP KEKGSPGQND QELKCSV         10         20         30         40         50         60
MASVAAARAV PVGSGLRGLQ RTLPLVVILG ATGTGKSTLA LQLGQRLGGE IVSADSMQVY
        70         80         90        100        110        120
EGLDIITNKV SAQEQRICRH HMISFVDPLV TNYTVVDFRN RATALIEDIF ARDKIPIVVG
       130        140        150        160        170        180
GTNYYIESLL WKVLVNTKPQ EMGTEKVIDR KVELEKEDGL VLHKRLSQVD PEMAAKLHPH
       190        200        210        220        230        240
DKRKVARSLQ VFEETGISHS EFLHRQHTEE GGGPLGGPLK FSNPCILWLH ADQAVLDERL
       250        260        270        280        290        300
DKRVDDMLAA GLLEELRDFH RRYNQKNVSE NSQDYQHGIF QSIGFKEFHE YLITEGKCTL
       310        320        330        340        350        360
ETSNQLLKKG IEALKQVTKR YARKQNRWVK NRFLSRPGPI VPPVYGLEVS DVSKWEESVL
       370        380        390        400        410        420
EPALEIVQSF IQGHKPTATP IKMPYNEAEN KRSYHLCDLC DRIIIGDREW AAHIKSKSHL
       430        440        450        460
NQLKKRRRLD SDAVNTIESQ SVSPDHNKEP KEKGSPGQND QELKCSV         10         20         30         40         50         60
MASVAAARAV PVGSGLRGLQ RTLPLVVILG ATGTGKSTLA LQLGQRLGGE IVSADSMQVY
        70         80         90        100        110        120
EGLDIITNKV SAQEQRICRH HMISFVDPLV TNYTVVDFRN RATALIEDIF ARDKIPIVVG
       130        140        150        160        170        180
GTNYYIESLL WKVLVNTKPQ EMGTEKVIDR KVELEKEDGL VLHKRLSQVD PEMAAKLHPH
       190        200        210        220        230        240
DKRKVARSLQ VFEETGISHS EFLHRQHTEE GGGPLGGPLK FSNPCILWLH ADQAVLDERL
       250        260        270        280        290        300
DKRVDDMLAA GLLEELRDFH RRYNQKNVSE NSQDYQHGIF QSIGFKEFHE YLITEGKCTL
       310        320        330        340        350        360
ETSNQLLKKG IEALKQVTKR YARKQNRWVK NRFLSRPGPI VPPVYGLEVS DVSKWEESVL
       370        380        390        400        410        420
EPALEIVQSF IQGHKPTATP IKMPYNEAEN KRSYHLCDLC DRIIIGDREW AAHIKSKSHL
       430        440        450        460
NQLKKRRRLD SDAVNTIESQ SVSPDHNKEP KEKGSPGQND QELKCSV         10         20         30         40         50         60
MASVAAARAV PVGSGLRGLQ RTLPLVVILG ATGTGKSTLA LQLGQRLGGE IVSADSMQVY
        70         80         90        100        110        120
EGLDIITNKV SAQEQRICRH HMISFVDPLV TNYTVVDFRN RATALIEDIF ARDKIPIVVG
       130        140        150        160        170        180
GTNYYIESLL WKVLVNTKPQ EMGTEKVIDR KVELEKEDGL VLHKRLSQVD PEMAAKLHPH
       190        200        210        220        230        240
DKRKVARSLQ VFEETGISHS EFLHRQHTEE GGGPLGGPLK FSNPCILWLH ADQAVLDERL
       250        260        270        280        290        300
DKRVDDMLAA GLLEELRDFH RRYNQKNVSE NSQDYQHGIF QSIGFKEFHE YLITEGKCTL
       310        320        330        340        350        360
ETSNQLLKKG IEALKQVTKR YARKQNRWVK NRFLSRPGPI VPPVYGLEVS DVSKWEESVL
       370        380        390        400        410        420
EPALEIVQSF IQGHKPTATP IKMPYNEAEN KRSYHLCDLC DRIIIGDREW AAHIKSKSHL
       430        440        450        460
NQLKKRRRLD SDAVNTIESQ SVSPDHNKEP KEKGSPGQND QELKCSV         10         20         30         40         50         60
MASVAAARAV PVGSGLRGLQ RTLPLVVILG ATGTGKSTLA LQLGQRLGGE IVSADSMQVY
        70         80         90        100        110        120
EGLDIITNKV SAQEQRICRH HMISFVDPLV TNYTVVDFRN RATALIEDIF ARDKIPIVVG
       130        140        150        160        170        180
GTNYYIESLL WKVLVNTKPQ EMGTEKVIDR KVELEKEDGL VLHKRLSQVD PEMAAKLHPH
       190        200        210        220        230        240
DKRKVARSLQ VFEETGISHS EFLHRQHTEE GGGPLGGPLK FSNPCILWLH ADQAVLDERL
       250        260        270        280        290        300
DKRVDDMLAA GLLEELRDFH RRYNQKNVSE NSQDYQHGIF QSIGFKEFHE YLITEGKCTL
       310        320        330        340        350        360
ETSNQLLKKG IEALKQVTKR YARKQNRWVK NRFLSRPGPI VPPVYGLEVS DVSKWEESVL
       370        380        390        400        410        420
EPALEIVQSF IQGHKPTATP IKMPYNEAEN KRSYHLCDLC DRIIIGDREW AAHIKSKSHL
       430        440        450        460
NQLKKRRRLD SDAVNTIESQ SVSPDHNKEP KEKGSPGQND QELKCSV         10         20         30         40         50         60
MASVAAARAV PVGSGLRGLQ RTLPLVVILG ATGTGKSTLA LQLGQRLGGE IVSADSMQVY
        70         80         90        100        110        120
EGLDIITNKV SAQEQRICRH HMISFVDPLV TNYTVVDFRN RATALIEDIF ARDKIPIVVG
       130        140        150        160        170        180
GTNYYIESLL WKVLVNTKPQ EMGTEKVIDR KVELEKEDGL VLHKRLSQVD PEMAAKLHPH
       190        200        210        220        230        240
DKRKVARSLQ VFEETGISHS EFLHRQHTEE GGGPLGGPLK FSNPCILWLH ADQAVLDERL
       250        260        270        280        290        300
DKRVDDMLAA GLLEELRDFH RRYNQKNVSE NSQDYQHGIF QSIGFKEFHE YLITEGKCTL
       310        320        330        340        350        360
ETSNQLLKKG IEALKQVTKR YARKQNRWVK NRFLSRPGPI VPPVYGLEVS DVSKWEESVL
       370        380        390        400        410        420
EPALEIVQSF IQGHKPTATP IKMPYNEAEN KRSYHLCDLC DRIIIGDREW AAHIKSKSHL
       430        440        450        460
NQLKKRRRLD SDAVNTIESQ SVSPDHNKEP KEKGSPGQND QELKCSV         10         20         30         40         50         60
MASVAAARAV PVGSGLRGLQ RTLPLVVILG ATGTGKSTLA LQLGQRLGGE IVSADSMQVY
        70         80         90        100        110        120
EGLDIITNKV SAQEQRICRH HMISFVDPLV TNYTVVDFRN RATALIEDIF ARDKIPIVVG
       130        140        150        160        170        180
GTNYYIESLL WKVLVNTKPQ EMGTEKVIDR KVELEKEDGL VLHKRLSQVD PEMAAKLHPH
       190        200        210        220        230        240
DKRKVARSLQ VFEETGISHS EFLHRQHTEE GGGPLGGPLK FSNPCILWLH ADQAVLDERL
       250        260        270        280        290        300
DKRVDDMLAA GLLEELRDFH RRYNQKNVSE NSQDYQHGIF QSIGFKEFHE YLITEGKCTL
       310        320        330        340        350        360
ETSNQLLKKG IEALKQVTKR YARKQNRWVK NRFLSRPGPI VPPVYGLEVS DVSKWEESVL
       370        380        390        400        410        420
EPALEIVQSF IQGHKPTATP IKMPYNEAEN KRSYHLCDLC DRIIIGDREW AAHIKSKSHL
       430        440        450        460
NQLKKRRRLD SDAVNTIESQ SVSPDHNKEP KEKGSPGQND QELKCSV         10         20         30         40         50         60
MASVAAARAV PVGSGLRGLQ RTLPLVVILG ATGTGKSTLA LQLGQRLGGE IVSADSMQVY
        70         80         90        100        110        120
EGLDIITNKV SAQEQRICRH HMISFVDPLV TNYTVVDFRN RATALIEDIF ARDKIPIVVG
       130        140        150        160        170        180
GTNYYIESLL WKVLVNTKPQ EMGTEKVIDR KVELEKEDGL VLHKRLSQVD PEMAAKLHPH
       190        200        210        220        230        240
DKRKVARSLQ VFEETGISHS EFLHRQHTEE GGGPLGGPLK FSNPCILWLH ADQAVLDERL
       250        260        270        280        290        300
DKRVDDMLAA GLLEELRDFH RRYNQKNVSE NSQDYQHGIF QSIGFKEFHE YLITEGKCTL
       310        320        330        340        350        360
ETSNQLLKKG IEALKQVTKR YARKQNRWVK NRFLSRPGPI VPPVYGLEVS DVSKWEESVL
       370        380        390        400        410        420
EPALEIVQSF IQGHKPTATP IKMPYNEAEN KRSYHLCDLC DRIIIGDREW AAHIKSKSHL
       430        440        450        460
NQLKKRRRLD SDAVNTIESQ SVSPDHNKEP KEKGSPGQND QELKCSV

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

5 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q9H3H1-1-unknown	MASVAA...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt81356
Q9H3H1-1-unknown	MASVAA...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt81357
Q9H3H1-48-unknown	GGEIVS...	48	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9H3H1-48-unknown	GGEIVS...	48	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt115603
Q9H3H1-142-unknown	MGTEKV...	142	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt81354
Q9H3H1-142-unknown	MGTEKV...	142	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt81355
Q9H3H1-142-unknown	MGTEKV...	142	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt107218
Q9H3H1-142-unknown	MGTEKV...	142	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt107219
Q9H3H1-247-unknown	MLAAGL...	247	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000439596
Q9H3H1-247-unknown	MLAAGL...	247	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt198423
Q9H3H1-247-unknown	MLAAGL...	247	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt198424
Q9H3H1-247-unknown	MLAAGL...	247	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt198421
Q9H3H1-247-unknown	MLAAGL...	247	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt198422
Q9H3H1-383-unknown	MPYNEA...	383	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000437896
Q9H3H1-383-unknown	MPYNEA...	383	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt199260
Q9H3H1-383-unknown	MPYNEA...	383	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt199263
Q9H3H1-383-unknown	MPYNEA...	383	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt199264
Q9H3H1-383-unknown	MPYNEA...	383	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt199261
Q9H3H1-383-unknown	MPYNEA...	383	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt199262

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...LKCSV	467	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...LKCSV	467	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt76976
...LKCSV	467	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt76973
...LKCSV	467	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt76972
...LKCSV	467	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt76975
...LKCSV	467	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt76974

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)