TopFIND 4.0

Q9H5U6: rRNA N6-adenosine-methyltransferase ZCCHC4 {ECO:0000305}

General Information

Protein names
- rRNA N6-adenosine-methyltransferase ZCCHC4 {ECO:0000305}
- 2.1.1.- {ECO:0000269|PubMed:30531910}
- Zinc finger CCHC domain-containing protein 4 {ECO:0000305}
Gene names ZCCHC4
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q9H5U6

1

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAASRNGFEA VEAEGSAGCR GSSGMEVVLP LDPAVPAPLC PHGPTLLFVK VTQGKEETRR 
        70         80         90        100        110        120 
FYACSACRDR KDCNFFQWED EKLSGARLAA REAHNRRCQP PLSRTQCVER YLKFIELPLT 
       130        140        150        160        170        180 
QRKFCQTCQQ LLLPDDWGQH SEHQVLGNVS ITQLRRPSQL LYPLENKKTN AQYLFADRSC 
       190        200        210        220        230        240 
QFLVDLLSAL GFRRVLCVGT PRLHELIKLT ASGDKKSNIK SLLLDIDFRY SQFYMEDSFC 
       250        260        270        280        290        300 
HYNMFNHHFF DGKTALEVCR AFLQEDKGEG IIMVTDPPFG GLVEPLAITF KKLIAMWKEG 
       310        320        330        340        350        360 
QSQDDSHKEL PIFWIFPYFF ESRICQFFPS FQMLDYQVDY DNHALYKHGK TGRKQSPVRI 
       370        380        390        400        410        420 
FTNIPPNKII LPTEEGYRFC SPCQRYVSLE NQHCELCNSC TSKDGRKWNH CFLCKKCVKP 
       430        440        450        460        470        480 
SWIHCSICNH CAVPDHSCEG PKHGCFICGE LDHKRSTCPN IATSKRANKA VRKQKQRKSN 
       490        500        510    
KMKMETTKGQ SMNHTSATRR KKRRERAHQY LGS

Isoforms

- Isoform 2 of Zinc finger CCHC domain-containing protein 4 - Isoform 3 of Zinc finger CCHC domain-containing protein 4 - Isoform 2 of rRNA N6-adenosine-methyltransferase ZCCHC4 - Isoform 3 of rRNA N6-adenosine-methyltransferase ZCCHC4

Sequence View

        10         20         30         40         50         60 
MAASRNGFEA VEAEGSAGCR GSSGMEVVLP LDPAVPAPLC PHGPTLLFVK VTQGKEETRR 
        70         80         90        100        110        120 
FYACSACRDR KDCNFFQWED EKLSGARLAA REAHNRRCQP PLSRTQCVER YLKFIELPLT 
       130        140        150        160        170        180 
QRKFCQTCQQ LLLPDDWGQH SEHQVLGNVS ITQLRRPSQL LYPLENKKTN AQYLFADRSC 
       190        200        210        220        230        240 
QFLVDLLSAL GFRRVLCVGT PRLHELIKLT ASGDKKSNIK SLLLDIDFRY SQFYMEDSFC 
       250        260        270        280        290        300 
HYNMFNHHFF DGKTALEVCR AFLQEDKGEG IIMVTDPPFG GLVEPLAITF KKLIAMWKEG 
       310        320        330        340        350        360 
QSQDDSHKEL PIFWIFPYFF ESRICQFFPS FQMLDYQVDY DNHALYKHGK TGRKQSPVRI 
       370        380        390        400        410        420 
FTNIPPNKII LPTEEGYRFC SPCQRYVSLE NQHCELCNSC TSKDGRKWNH CFLCKKCVKP 
       430        440        450        460        470        480 
SWIHCSICNH CAVPDHSCEG PKHGCFICGE LDHKRSTCPN IATSKRANKA VRKQKQRKSN 
       490        500        510    
KMKMETTKGQ SMNHTSATRR KKRRERAHQY LGS         10         20         30         40         50         60 
MAASRNGFEA VEAEGSAGCR GSSGMEVVLP LDPAVPAPLC PHGPTLLFVK VTQGKEETRR 
        70         80         90        100        110        120 
FYACSACRDR KDCNFFQWED EKLSGARLAA REAHNRRCQP PLSRTQCVER YLKFIELPLT 
       130        140        150        160        170        180 
QRKFCQTCQQ LLLPDDWGQH SEHQVLGNVS ITQLRRPSQL LYPLENKKTN AQYLFADRSC 
       190        200        210        220        230        240 
QFLVDLLSAL GFRRVLCVGT PRLHELIKLT ASGDKKSNIK SLLLDIDFRY SQFYMEDSFC 
       250        260        270        280        290        300 
HYNMFNHHFF DGKTALEVCR AFLQEDKGEG IIMVTDPPFG GLVEPLAITF KKLIAMWKEG 
       310        320        330        340        350        360 
QSQDDSHKEL PIFWIFPYFF ESRICQFFPS FQMLDYQVDY DNHALYKHGK TGRKQSPVRI 
       370        380        390        400        410        420 
FTNIPPNKII LPTEEGYRFC SPCQRYVSLE NQHCELCNSC TSKDGRKWNH CFLCKKCVKP 
       430        440        450        460        470        480 
SWIHCSICNH CAVPDHSCEG PKHGCFICGE LDHKRSTCPN IATSKRANKA VRKQKQRKSN 
       490        500        510    
KMKMETTKGQ SMNHTSATRR KKRRERAHQY LGS         10         20         30         40         50         60 
MAASRNGFEA VEAEGSAGCR GSSGMEVVLP LDPAVPAPLC PHGPTLLFVK VTQGKEETRR 
        70         80         90        100        110        120 
FYACSACRDR KDCNFFQWED EKLSGARLAA REAHNRRCQP PLSRTQCVER YLKFIELPLT 
       130        140        150        160        170        180 
QRKFCQTCQQ LLLPDDWGQH SEHQVLGNVS ITQLRRPSQL LYPLENKKTN AQYLFADRSC 
       190        200        210        220        230        240 
QFLVDLLSAL GFRRVLCVGT PRLHELIKLT ASGDKKSNIK SLLLDIDFRY SQFYMEDSFC 
       250        260        270        280        290        300 
HYNMFNHHFF DGKTALEVCR AFLQEDKGEG IIMVTDPPFG GLVEPLAITF KKLIAMWKEG 
       310        320        330        340        350        360 
QSQDDSHKEL PIFWIFPYFF ESRICQFFPS FQMLDYQVDY DNHALYKHGK TGRKQSPVRI 
       370        380        390        400        410        420 
FTNIPPNKII LPTEEGYRFC SPCQRYVSLE NQHCELCNSC TSKDGRKWNH CFLCKKCVKP 
       430        440        450        460        470        480 
SWIHCSICNH CAVPDHSCEG PKHGCFICGE LDHKRSTCPN IATSKRANKA VRKQKQRKSN 
       490        500        510    
KMKMETTKGQ SMNHTSATRR KKRRERAHQY LGS         10         20         30         40         50         60 
MAASRNGFEA VEAEGSAGCR GSSGMEVVLP LDPAVPAPLC PHGPTLLFVK VTQGKEETRR 
        70         80         90        100        110        120 
FYACSACRDR KDCNFFQWED EKLSGARLAA REAHNRRCQP PLSRTQCVER YLKFIELPLT 
       130        140        150        160        170        180 
QRKFCQTCQQ LLLPDDWGQH SEHQVLGNVS ITQLRRPSQL LYPLENKKTN AQYLFADRSC 
       190        200        210        220        230        240 
QFLVDLLSAL GFRRVLCVGT PRLHELIKLT ASGDKKSNIK SLLLDIDFRY SQFYMEDSFC 
       250        260        270        280        290        300 
HYNMFNHHFF DGKTALEVCR AFLQEDKGEG IIMVTDPPFG GLVEPLAITF KKLIAMWKEG 
       310        320        330        340        350        360 
QSQDDSHKEL PIFWIFPYFF ESRICQFFPS FQMLDYQVDY DNHALYKHGK TGRKQSPVRI 
       370        380        390        400        410        420 
FTNIPPNKII LPTEEGYRFC SPCQRYVSLE NQHCELCNSC TSKDGRKWNH CFLCKKCVKP 
       430        440        450        460        470        480 
SWIHCSICNH CAVPDHSCEG PKHGCFICGE LDHKRSTCPN IATSKRANKA VRKQKQRKSN 
       490        500        510    
KMKMETTKGQ SMNHTSATRR KKRRERAHQY LGS



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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9H5U6-1-unknown MAASRN... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9H5U6-1-unknown MAASRN... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt95035
    Q9H5U6-1-unknown MAASRN... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt95036

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)