TopFIND 4.0

Q9H611: ATP-dependent DNA helicase PIF1 {ECO:0000255|HAMAP-Rule:MF_03176}

General Information

Protein names
- ATP-dependent DNA helicase PIF1 {ECO:0000255|HAMAP-Rule:MF_03176}
- 3.6.4.12 {ECO:0000255|HAMAP-Rule:MF_03176}
- DNA repair and recombination helicase PIF1 {ECO:0000255|HAMAP-Rule:MF_03176}
- PIF1/RRM3 DNA helicase-like protein
Gene names PIF1
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q9H611

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MLSGIEAAAG EYEDSELRCR VAVEELSPGG QPRRRQALRT AELSLGRNER RELMLRLQAP 
        70         80         90        100        110        120 
GPAGRPRCFP LRAARLFTRF AEAGRSTLRL PAHDTPGAGA VQLLLSDCPP DRLRRFLRTL 
       130        140        150        160        170        180 
RLKLAAAPGP GPASARAQLL GPRPRDFVTI SPVQPEERRL RAATRVPDTT LVKRPVEPQA 
       190        200        210        220        230        240 
GAEPSTEAPR WPLPVKRLSL PSTKPQLSEE QAAVLRAVLK GQSIFFTGSA GTGKSYLLKR 
       250        260        270        280        290        300 
ILGSLPPTGT VATASTGVAA CHIGGTTLHA FAGIGSGQAP LAQCVALAQR PGVRQGWLNC 
       310        320        330        340        350        360 
QRLVIDEISM VEADLFDKLE AVARAVRQQN KPFGGIQLII CGDFLQLPPV TKGSQPPRFC 
       370        380        390        400        410        420 
FQSKSWKRCV PVTLELTKVW RQADQTFISL LQAVRLGRCS DEVTRQLQAT ASHKVGRDGI 
       430        440        450        460        470        480 
VATRLCTHQD DVALTNERRL QELPGKVHRF EAMDSNPELA STLDAQCPVS QLLQLKLGAQ 
       490        500        510        520        530        540 
VMLVKNLSVS RGLVNGARGV VVGFEAEGRG LPQVRFLCGV TEVIHADRWT VQATGGQLLS 
       550        560        570        580        590        600 
RQQLPLQLAW AMSIHKSQGM TLDCVEISLG RVFASGQAYV ALSRARSLQG LRVLDFDPMA 
       610        620        630        640    
VRCDPRVLHF YATLRRGRSL SLESPDDDEA ASDQENMDPI L

Isoforms

- Isoform 2 of ATP-dependent DNA helicase PIF1 - Isoform 3 of ATP-dependent DNA helicase PIF1 - Isoform 4 of ATP-dependent DNA helicase PIF1

Sequence View

        10         20         30         40         50         60 
MLSGIEAAAG EYEDSELRCR VAVEELSPGG QPRRRQALRT AELSLGRNER RELMLRLQAP 
        70         80         90        100        110        120 
GPAGRPRCFP LRAARLFTRF AEAGRSTLRL PAHDTPGAGA VQLLLSDCPP DRLRRFLRTL 
       130        140        150        160        170        180 
RLKLAAAPGP GPASARAQLL GPRPRDFVTI SPVQPEERRL RAATRVPDTT LVKRPVEPQA 
       190        200        210        220        230        240 
GAEPSTEAPR WPLPVKRLSL PSTKPQLSEE QAAVLRAVLK GQSIFFTGSA GTGKSYLLKR 
       250        260        270        280        290        300 
ILGSLPPTGT VATASTGVAA CHIGGTTLHA FAGIGSGQAP LAQCVALAQR PGVRQGWLNC 
       310        320        330        340        350        360 
QRLVIDEISM VEADLFDKLE AVARAVRQQN KPFGGIQLII CGDFLQLPPV TKGSQPPRFC 
       370        380        390        400        410        420 
FQSKSWKRCV PVTLELTKVW RQADQTFISL LQAVRLGRCS DEVTRQLQAT ASHKVGRDGI 
       430        440        450        460        470        480 
VATRLCTHQD DVALTNERRL QELPGKVHRF EAMDSNPELA STLDAQCPVS QLLQLKLGAQ 
       490        500        510        520        530        540 
VMLVKNLSVS RGLVNGARGV VVGFEAEGRG LPQVRFLCGV TEVIHADRWT VQATGGQLLS 
       550        560        570        580        590        600 
RQQLPLQLAW AMSIHKSQGM TLDCVEISLG RVFASGQAYV ALSRARSLQG LRVLDFDPMA 
       610        620        630        640    
VRCDPRVLHF YATLRRGRSL SLESPDDDEA ASDQENMDPI L         10         20         30         40         50         60 
MLSGIEAAAG EYEDSELRCR VAVEELSPGG QPRRRQALRT AELSLGRNER RELMLRLQAP 
        70         80         90        100        110        120 
GPAGRPRCFP LRAARLFTRF AEAGRSTLRL PAHDTPGAGA VQLLLSDCPP DRLRRFLRTL 
       130        140        150        160        170        180 
RLKLAAAPGP GPASARAQLL GPRPRDFVTI SPVQPEERRL RAATRVPDTT LVKRPVEPQA 
       190        200        210        220        230        240 
GAEPSTEAPR WPLPVKRLSL PSTKPQLSEE QAAVLRAVLK GQSIFFTGSA GTGKSYLLKR 
       250        260        270        280        290        300 
ILGSLPPTGT VATASTGVAA CHIGGTTLHA FAGIGSGQAP LAQCVALAQR PGVRQGWLNC 
       310        320        330        340        350        360 
QRLVIDEISM VEADLFDKLE AVARAVRQQN KPFGGIQLII CGDFLQLPPV TKGSQPPRFC 
       370        380        390        400        410        420 
FQSKSWKRCV PVTLELTKVW RQADQTFISL LQAVRLGRCS DEVTRQLQAT ASHKVGRDGI 
       430        440        450        460        470        480 
VATRLCTHQD DVALTNERRL QELPGKVHRF EAMDSNPELA STLDAQCPVS QLLQLKLGAQ 
       490        500        510        520        530        540 
VMLVKNLSVS RGLVNGARGV VVGFEAEGRG LPQVRFLCGV TEVIHADRWT VQATGGQLLS 
       550        560        570        580        590        600 
RQQLPLQLAW AMSIHKSQGM TLDCVEISLG RVFASGQAYV ALSRARSLQG LRVLDFDPMA 
       610        620        630        640    
VRCDPRVLHF YATLRRGRSL SLESPDDDEA ASDQENMDPI L         10         20         30         40         50         60 
MLSGIEAAAG EYEDSELRCR VAVEELSPGG QPRRRQALRT AELSLGRNER RELMLRLQAP 
        70         80         90        100        110        120 
GPAGRPRCFP LRAARLFTRF AEAGRSTLRL PAHDTPGAGA VQLLLSDCPP DRLRRFLRTL 
       130        140        150        160        170        180 
RLKLAAAPGP GPASARAQLL GPRPRDFVTI SPVQPEERRL RAATRVPDTT LVKRPVEPQA 
       190        200        210        220        230        240 
GAEPSTEAPR WPLPVKRLSL PSTKPQLSEE QAAVLRAVLK GQSIFFTGSA GTGKSYLLKR 
       250        260        270        280        290        300 
ILGSLPPTGT VATASTGVAA CHIGGTTLHA FAGIGSGQAP LAQCVALAQR PGVRQGWLNC 
       310        320        330        340        350        360 
QRLVIDEISM VEADLFDKLE AVARAVRQQN KPFGGIQLII CGDFLQLPPV TKGSQPPRFC 
       370        380        390        400        410        420 
FQSKSWKRCV PVTLELTKVW RQADQTFISL LQAVRLGRCS DEVTRQLQAT ASHKVGRDGI 
       430        440        450        460        470        480 
VATRLCTHQD DVALTNERRL QELPGKVHRF EAMDSNPELA STLDAQCPVS QLLQLKLGAQ 
       490        500        510        520        530        540 
VMLVKNLSVS RGLVNGARGV VVGFEAEGRG LPQVRFLCGV TEVIHADRWT VQATGGQLLS 
       550        560        570        580        590        600 
RQQLPLQLAW AMSIHKSQGM TLDCVEISLG RVFASGQAYV ALSRARSLQG LRVLDFDPMA 
       610        620        630        640    
VRCDPRVLHF YATLRRGRSL SLESPDDDEA ASDQENMDPI L



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...MDPIL 641 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...MDPIL 641 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt80806

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)