TopFIND 4.0

Q9H7P6: Multivesicular body subunit 12B

General Information

Protein names
- Multivesicular body subunit 12B
- ESCRT-I complex subunit MVB12B
- Protein FAM125B
Gene names MVB12B
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q9H7P6

1

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MRSCFCVRRS RDPPPPQPPP PPPQRGTDQS TMPEVKDLSE ALPETSMDPI TGVGVVASRN 
        70         80         90        100        110        120 
RAPTGYDVVA QTADGVDADL WKDGLFKSKV TRYLCFTRSF SKENSHLGNV LVDMKLIDIK 
       130        140        150        160        170        180 
DTLPVGFIPI QETVDTQEVA FRKKRLCIKF IPRDSTEAAI CDIRIMGRTK QAPPQYTFIG 
       190        200        210        220        230        240 
ELNSMGIWYR MGRVPRNHDS SQPTTPSQSS AASTPAPNLP RHISLTLPAT FRGRNSTRTD 
       250        260        270        280        290        300 
YEYQHSNLYA ISAMDGVPFM ISEKFSCVPE SMQPFDLLGI TIKSLAEIEK EYEYSFRTEQ 
       310    
SAAARLPPSP TRCQQIPQS

Isoforms

- Isoform 2 of Multivesicular body subunit 12B

Sequence View

        10         20         30         40         50         60 
MRSCFCVRRS RDPPPPQPPP PPPQRGTDQS TMPEVKDLSE ALPETSMDPI TGVGVVASRN 
        70         80         90        100        110        120 
RAPTGYDVVA QTADGVDADL WKDGLFKSKV TRYLCFTRSF SKENSHLGNV LVDMKLIDIK 
       130        140        150        160        170        180 
DTLPVGFIPI QETVDTQEVA FRKKRLCIKF IPRDSTEAAI CDIRIMGRTK QAPPQYTFIG 
       190        200        210        220        230        240 
ELNSMGIWYR MGRVPRNHDS SQPTTPSQSS AASTPAPNLP RHISLTLPAT FRGRNSTRTD 
       250        260        270        280        290        300 
YEYQHSNLYA ISAMDGVPFM ISEKFSCVPE SMQPFDLLGI TIKSLAEIEK EYEYSFRTEQ 
       310    
SAAARLPPSP TRCQQIPQS



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Physiological Relevance:


Evidence Codes:


Methodology:


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Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

1 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9H7P6-1-unknown MRSCFC... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9H7P6-1-unknown MRSCFC... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt80503

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...PNLPRH 221 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt76121
    ...QIPQS 319 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)