TopFIND 4.0

Q9H7Z6: Histone acetyltransferase KAT8

General Information

Protein names
- Histone acetyltransferase KAT8
- 2.3.1.48 {ECO:0000269|PubMed:10786633, ECO:0000269|PubMed:21217699, ECO:0000269|PubMed:22020126, ECO:0000269|PubMed:22547026, ECO:0000305|PubMed:16543150}
- Lysine acetyltransferase 8
- MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1
- MYST-1
- hMOF
Gene names KAT8
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q9H7Z6

3

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAAQGAAAAV AAGTSGVAGE GEPGPGENAA AEGTAPSPGR VSPPTPARGE PEVTVEIGET 
        70         80         90        100        110        120 
YLCRRPDSTW HSAEVIQSRV NDQEGREEFY VHYVGFNRRL DEWVDKNRLA LTKTVKDAVQ 
       130        140        150        160        170        180 
KNSEKYLSEL AEQPERKITR NQKRKHDEIN HVQKTYAEMD PTTAALEKEH EAITKVKYVD 
       190        200        210        220        230        240 
KIHIGNYEID AWYFSPFPED YGKQPKLWLC EYCLKYMKYE KSYRFHLGQC QWRQPPGKEI 
       250        260        270        280        290        300 
YRKSNISVYE VDGKDHKIYC QNLCLLAKLF LDHKTLYFDV EPFVFYILTE VDRQGAHIVG 
       310        320        330        340        350        360 
YFSKEKESPD GNNVACILTL PPYQRRGYGK FLIAFSYELS KLESTVGSPE KPLSDLGKLS 
       370        380        390        400        410        420 
YRSYWSWVLL EILRDFRGTL SIKDLSQMTS ITQNDIISTL QSLNMVKYWK GQHVICVTPK 
       430        440        450    
LVEEHLKSAQ YKKPPITVDS VCLKWAPPKH KQVKLSKK

Isoforms

- Isoform 2 of Histone acetyltransferase KAT8

Sequence View

        10         20         30         40         50         60 
MAAQGAAAAV AAGTSGVAGE GEPGPGENAA AEGTAPSPGR VSPPTPARGE PEVTVEIGET 
        70         80         90        100        110        120 
YLCRRPDSTW HSAEVIQSRV NDQEGREEFY VHYVGFNRRL DEWVDKNRLA LTKTVKDAVQ 
       130        140        150        160        170        180 
KNSEKYLSEL AEQPERKITR NQKRKHDEIN HVQKTYAEMD PTTAALEKEH EAITKVKYVD 
       190        200        210        220        230        240 
KIHIGNYEID AWYFSPFPED YGKQPKLWLC EYCLKYMKYE KSYRFHLGQC QWRQPPGKEI 
       250        260        270        280        290        300 
YRKSNISVYE VDGKDHKIYC QNLCLLAKLF LDHKTLYFDV EPFVFYILTE VDRQGAHIVG 
       310        320        330        340        350        360 
YFSKEKESPD GNNVACILTL PPYQRRGYGK FLIAFSYELS KLESTVGSPE KPLSDLGKLS 
       370        380        390        400        410        420 
YRSYWSWVLL EILRDFRGTL SIKDLSQMTS ITQNDIISTL QSLNMVKYWK GQHVICVTPK 
       430        440        450    
LVEEHLKSAQ YKKPPITVDS VCLKWAPPKH KQVKLSKK



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Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9H7Z6-2-unknown MAAQGA... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9H7Z6-1-unknown MAAQGA... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt78599
    Q9H7Z6-2-Acetylation AAQGAA... 2 acetylation- inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9H7Z6-2-Acetylation AAQGAA... 2 acetylation- inferred from isoform by sequence similarity unknown TopFIND inferred from TNt111082

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...KLSKK 458 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)