Q9H867: Protein-lysine methyltransferase METTL21D

General Information

Protein names	- Protein-lysine methyltransferase METTL21D - 2.1.1.- - Methyltransferase-like protein 21D - VCP lysine methyltransferase - VCP-KMT - Valosin-containing protein lysine methyltransferase
Gene names	VCPKMT
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9H867

3 N-termini

3 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 1 of Protein-lysine methyltransferase METTL21D - Isoform 2 of Protein-lysine methyltransferase METTL21D - Isoform 3 of Protein-lysine methyltransferase METTL21D - Isoform 5 of Protein-lysine methyltransferase METTL21D

Sequence View

        10         20         30         40         50         60
MADTLESSLE DPLRSFVRVL EKRDGTVLRL QQYSSGGVGC VVWDAAIVLS KYLETPEFSG
        70         80         90        100        110        120
DGAHALSRRS VLELGSGTGA VGLMAATLGA DVVVTDLEEL QDLLKMNINM NKHLVTGSVQ
       130        140        150        160        170        180
AKVLKWGEEI EGFPSPPDFI LMADCIYYEE SLEPLLKTLK DISGFETCII CCYEQRTMGK
       190        200        210        220
NPEIEKKYFE LLQLDFDFEK IPLEKHDEEY RSEDIHIIYI RKKKSKFPS         10         20         30         40         50         60
MADTLESSLE DPLRSFVRVL EKRDGTVLRL QQYSSGGVGC VVWDAAIVLS KYLETPEFSG
        70         80         90        100        110        120
DGAHALSRRS VLELGSGTGA VGLMAATLGA DVVVTDLEEL QDLLKMNINM NKHLVTGSVQ
       130        140        150        160        170        180
AKVLKWGEEI EGFPSPPDFI LMADCIYYEE SLEPLLKTLK DISGFETCII CCYEQRTMGK
       190        200        210        220
NPEIEKKYFE LLQLDFDFEK IPLEKHDEEY RSEDIHIIYI RKKKSKFPS         10         20         30         40         50         60
MADTLESSLE DPLRSFVRVL EKRDGTVLRL QQYSSGGVGC VVWDAAIVLS KYLETPEFSG
        70         80         90        100        110        120
DGAHALSRRS VLELGSGTGA VGLMAATLGA DVVVTDLEEL QDLLKMNINM NKHLVTGSVQ
       130        140        150        160        170        180
AKVLKWGEEI EGFPSPPDFI LMADCIYYEE SLEPLLKTLK DISGFETCII CCYEQRTMGK
       190        200        210        220
NPEIEKKYFE LLQLDFDFEK IPLEKHDEEY RSEDIHIIYI RKKKSKFPS         10         20         30         40         50         60
MADTLESSLE DPLRSFVRVL EKRDGTVLRL QQYSSGGVGC VVWDAAIVLS KYLETPEFSG
        70         80         90        100        110        120
DGAHALSRRS VLELGSGTGA VGLMAATLGA DVVVTDLEEL QDLLKMNINM NKHLVTGSVQ
       130        140        150        160        170        180
AKVLKWGEEI EGFPSPPDFI LMADCIYYEE SLEPLLKTLK DISGFETCII CCYEQRTMGK
       190        200        210        220
NPEIEKKYFE LLQLDFDFEK IPLEKHDEEY RSEDIHIIYI RKKKSKFPS

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9H867-1-unknown	MADTLE...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt81680
Q9H867-1-unknown	MADTLE...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt81681
Q9H867-2-unknown	MADTLE...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9H867-2-Acetylation	ADTLES...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9H867-2-Acetylation	ADTLES...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q9H867-2-Acetylation	ADTLES...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt110934
Q9H867-2-Acetylation	ADTLES...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt110935

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...AATLGA	89	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt77298
...AATLGA	89	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt91465
...KKYFEL	190	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt77297
...KKYFEL	190	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt91594
...SKFPS	229	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...SKFPS	229		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...SKFPS	229		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)