TopFIND 4.0

Q9H9P8: L-2-hydroxyglutarate dehydrogenase, mitochondrial

General Information

Protein names
- L-2-hydroxyglutarate dehydrogenase, mitochondrial
- 1.1.99.2
- Duranin
Gene names L2HGDH
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q9H9P8

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MVPALRYLVG ACGRARGLFA GGSPGACGFA SGRPRPLCGG SRSASTSSFD IVIVGGGIVG 
        70         80         90        100        110        120 
LASARALILR HPSLSIGVLE KEKDLAVHQT GHNSGVIHSG IYYKPESLKA KLCVQGAALL 
       130        140        150        160        170        180 
YEYCQQKGIS YKQCGKLIVA VEQEEIPRLQ ALYEKGLQNG VPGLRLIQQE DIKKKEPYCR 
       190        200        210        220        230        240 
GLMAIDCPHT GIVDYRQVAL SFAQDFQEAG GSVLTNFEVK GIEMAKESPS RSIDGMQYPI 
       250        260        270        280        290        300 
VIKNTKGEEI RCQYVVTCAG LYSDRISELS GCTPDPRIVP FRGDYLLLKP EKCYLVKGNI 
       310        320        330        340        350        360 
YPVPDSRFPF LGVHFTPRMD GSIWLGPNAV LAFKREGYRP FDFSATDVMD IIINSGLIKL 
       370        380        390        400        410        420 
ASQNFSYGVT EMYKACFLGA TVKYLQKFIP EITISDILRG PAGVRAQALD RDGNLVEDFV 
       430        440        450        460    
FDAGVGDIGN RILHVRNAPS PAATSSIAIS GMIADEVQQR FEL

Isoforms

- Isoform 2 of L-2-hydroxyglutarate dehydrogenase, mitochondrial

Sequence View

        10         20         30         40         50         60 
MVPALRYLVG ACGRARGLFA GGSPGACGFA SGRPRPLCGG SRSASTSSFD IVIVGGGIVG 
        70         80         90        100        110        120 
LASARALILR HPSLSIGVLE KEKDLAVHQT GHNSGVIHSG IYYKPESLKA KLCVQGAALL 
       130        140        150        160        170        180 
YEYCQQKGIS YKQCGKLIVA VEQEEIPRLQ ALYEKGLQNG VPGLRLIQQE DIKKKEPYCR 
       190        200        210        220        230        240 
GLMAIDCPHT GIVDYRQVAL SFAQDFQEAG GSVLTNFEVK GIEMAKESPS RSIDGMQYPI 
       250        260        270        280        290        300 
VIKNTKGEEI RCQYVVTCAG LYSDRISELS GCTPDPRIVP FRGDYLLLKP EKCYLVKGNI 
       310        320        330        340        350        360 
YPVPDSRFPF LGVHFTPRMD GSIWLGPNAV LAFKREGYRP FDFSATDVMD IIINSGLIKL 
       370        380        390        400        410        420 
ASQNFSYGVT EMYKACFLGA TVKYLQKFIP EITISDILRG PAGVRAQALD RDGNLVEDFV 
       430        440        450        460    
FDAGVGDIGN RILHVRNAPS PAATSSIAIS GMIADEVQQR FEL



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9H9P8-1-unknown MVPALR... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt79313
    Q9H9P8-52-unknown VIVGGG... 52 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9H9P8-52-unknown VIVGGG... 52 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt115652

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...QRFEL 463 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)