TopFIND 4.0

Q9H9V9: 2-oxoglutarate and iron-dependent oxygenase JMJD4 {ECO:0000303|PubMed:24486019}

General Information

Protein names
- 2-oxoglutarate and iron-dependent oxygenase JMJD4 {ECO:0000303|PubMed:24486019}
- 1.14.11.- {ECO:0000269|PubMed:24486019}
- JmjC domain-containing protein 4
- Jumonji domain-containing protein 4
- Lysyl-hydroxylase JMJD4 {ECO:0000303|PubMed:24486019}
Gene names JMJD4
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q9H9V9

3

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MRAGPEPQAL AGQKRGALRL LVPRLVLTVS APAEVRRRVL RPVLSWMDRE TRALADSHFR 
        70         80         90        100        110        120 
GLGVDVPGVG QAPGRVAFVS EPGAFSYADF VRGFLLPNLP CVFSSAFTQG WGSRRRWVTP 
       130        140        150        160        170        180 
AGRPDFDHLL RTYGDVVVPV ANCGVQEYNS NPKEHMTLRD YITYWKEYIQ AGYSSPRGCL 
       190        200        210        220        230        240 
YLKDWHLCRD FPVEDVFTLP VYFSSDWLNE FWDALDVDDY RFVYAGPAGS WSPFHADIFR 
       250        260        270        280        290        300 
SFSWSVNVCG RKKWLLFPPG QEEALRDRHG NLPYDVTSPA LCDTHLHPRN QLAGPPLEIT 
       310        320        330        340        350        360 
QEAGEMVFVP SGWHHQVHNL DDTISINHNW VNGFNLANMW RFLQQELCAV QEEVSEWRDS 
       370        380        390        400        410        420 
MPDWHHHCQV IMRSCSGINF EEFYHFLKVI AEKRLLVLRE AAAEDGAGLG FEQAAFDVGR 
       430        440        450        460    
ITEVLASLVA HPDFQRVDTS AFSPQPKELL QQLREAVDAA AAP

Isoforms

- Isoform 2 of JmjC domain-containing protein 4 - Isoform 2 of 2-oxoglutarate and iron-dependent oxygenase JMJD4

Sequence View

        10         20         30         40         50         60 
MRAGPEPQAL AGQKRGALRL LVPRLVLTVS APAEVRRRVL RPVLSWMDRE TRALADSHFR 
        70         80         90        100        110        120 
GLGVDVPGVG QAPGRVAFVS EPGAFSYADF VRGFLLPNLP CVFSSAFTQG WGSRRRWVTP 
       130        140        150        160        170        180 
AGRPDFDHLL RTYGDVVVPV ANCGVQEYNS NPKEHMTLRD YITYWKEYIQ AGYSSPRGCL 
       190        200        210        220        230        240 
YLKDWHLCRD FPVEDVFTLP VYFSSDWLNE FWDALDVDDY RFVYAGPAGS WSPFHADIFR 
       250        260        270        280        290        300 
SFSWSVNVCG RKKWLLFPPG QEEALRDRHG NLPYDVTSPA LCDTHLHPRN QLAGPPLEIT 
       310        320        330        340        350        360 
QEAGEMVFVP SGWHHQVHNL DDTISINHNW VNGFNLANMW RFLQQELCAV QEEVSEWRDS 
       370        380        390        400        410        420 
MPDWHHHCQV IMRSCSGINF EEFYHFLKVI AEKRLLVLRE AAAEDGAGLG FEQAAFDVGR 
       430        440        450        460    
ITEVLASLVA HPDFQRVDTS AFSPQPKELL QQLREAVDAA AAP         10         20         30         40         50         60 
MRAGPEPQAL AGQKRGALRL LVPRLVLTVS APAEVRRRVL RPVLSWMDRE TRALADSHFR 
        70         80         90        100        110        120 
GLGVDVPGVG QAPGRVAFVS EPGAFSYADF VRGFLLPNLP CVFSSAFTQG WGSRRRWVTP 
       130        140        150        160        170        180 
AGRPDFDHLL RTYGDVVVPV ANCGVQEYNS NPKEHMTLRD YITYWKEYIQ AGYSSPRGCL 
       190        200        210        220        230        240 
YLKDWHLCRD FPVEDVFTLP VYFSSDWLNE FWDALDVDDY RFVYAGPAGS WSPFHADIFR 
       250        260        270        280        290        300 
SFSWSVNVCG RKKWLLFPPG QEEALRDRHG NLPYDVTSPA LCDTHLHPRN QLAGPPLEIT 
       310        320        330        340        350        360 
QEAGEMVFVP SGWHHQVHNL DDTISINHNW VNGFNLANMW RFLQQELCAV QEEVSEWRDS 
       370        380        390        400        410        420 
MPDWHHHCQV IMRSCSGINF EEFYHFLKVI AEKRLLVLRE AAAEDGAGLG FEQAAFDVGR 
       430        440        450        460    
ITEVLASLVA HPDFQRVDTS AFSPQPKELL QQLREAVDAA AAP



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...AAAAP 463 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...AAAAP 463 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt73951

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)