Q9HCC9: Lateral signaling target protein 2 homolog

General Information

Protein names	- Lateral signaling target protein 2 homolog - hLst2 - Zinc finger FYVE domain-containing protein 28
Gene names	ZFYVE28
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9HCC9

3 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Lateral signaling target protein 2 homolog - Isoform 3 of Lateral signaling target protein 2 homolog - Isoform 4 of Lateral signaling target protein 2 homolog - Isoform 5 of Lateral signaling target protein 2 homolog - Isoform 6 of Lateral signaling target protein 2 homolog - Isoform 7 of Lateral signaling target protein 2 homolog - Isoform 8 of Lateral signaling target protein 2 homolog

Sequence View

        10         20         30         40         50         60
MMNRFRKWLY KPKRSDPQLL ARFYYADEEL NQVAAELDSL DGRKDPQRCT LLVSQFRSCQ
        70         80         90        100        110        120
DNVLNIINQI MDECIPQDRA PRDFCVKFPE EIRHDNLAGQ LWFGAECLAA GSIIMNRELE
       130        140        150        160        170        180
SMAMRPLAKE LTRSLEDVRG ALRDQALRDL NTYTEKMREA LRHFDVLFAE FELSYVSAMV
       190        200        210        220        230        240
PVKSPREYYV QQEVIVLFCE TVERALDFGY LTQDMIDDYE PALMFSIPRL AIVCGLVVYA
       250        260        270        280        290        300
DGPLNLDRKV EDMSELFRPF HTLLRKIRDL LQTLTEEELH TLERNLCISQ DVEFPIRADV
       310        320        330        340        350        360
QGPAALAPAL SAPLPPEGPL SAKAKDPDAE LACSMQYDDQ ELEQLSRMVH RAGDEMSSLL
       370        380        390        400        410        420
SPPIACQSPA HRPGAEGSPG GEASPGRPRL RSGSDEEERV FFMDDVEGTA EALARPESPA
       430        440        450        460        470        480
GPFGWAGSTW ADPQEKGQGG PGGAAGISLP ASEKEEDLSN NNLEAEGTDG ASLAGTSSCS
       490        500        510        520        530        540
CLDSRLHLDG WEVGADDAET AEMIAHRTGG MKLSATVIFN PKSPTSLDSA VATQEAASEP
       550        560        570        580        590        600
VAEGMDGGPH KLSTGATNCL LHSCVCCGSC GDSREDVVER LREKCSPGGV IGASYAAGLA
       610        620        630        640        650        660
KASDRAPERQ EEAPPPSEDA SNGREPKAPT SDKCLPHTSG SQVDTASGLQ GEAGVAGQQE
       670        680        690        700        710        720
PEARELHAGS PSAHEAPQAL SGSSSSTAGS CSSDKMGPEA APAATHAAPQ ATREKIRSRF
       730        740        750        760        770        780
HGSHDLIHRL FVCISGVADQ LQTNYASDLR SILKTLFEVM ATKPETDDKE KLRKVTQTLR
       790        800        810        820        830        840
SAALEDCALC QETLSSSELA AKTRDGDFED PPEWVPDEAC GFCTACKAPF TVIRRKHHCR
       850        860        870        880
SCGKIFCSRC SSHSAPLPRY GQVKPVRVCT HCYMFHVTPF YSDKAGL         10         20         30         40         50         60
MMNRFRKWLY KPKRSDPQLL ARFYYADEEL NQVAAELDSL DGRKDPQRCT LLVSQFRSCQ
        70         80         90        100        110        120
DNVLNIINQI MDECIPQDRA PRDFCVKFPE EIRHDNLAGQ LWFGAECLAA GSIIMNRELE
       130        140        150        160        170        180
SMAMRPLAKE LTRSLEDVRG ALRDQALRDL NTYTEKMREA LRHFDVLFAE FELSYVSAMV
       190        200        210        220        230        240
PVKSPREYYV QQEVIVLFCE TVERALDFGY LTQDMIDDYE PALMFSIPRL AIVCGLVVYA
       250        260        270        280        290        300
DGPLNLDRKV EDMSELFRPF HTLLRKIRDL LQTLTEEELH TLERNLCISQ DVEFPIRADV
       310        320        330        340        350        360
QGPAALAPAL SAPLPPEGPL SAKAKDPDAE LACSMQYDDQ ELEQLSRMVH RAGDEMSSLL
       370        380        390        400        410        420
SPPIACQSPA HRPGAEGSPG GEASPGRPRL RSGSDEEERV FFMDDVEGTA EALARPESPA
       430        440        450        460        470        480
GPFGWAGSTW ADPQEKGQGG PGGAAGISLP ASEKEEDLSN NNLEAEGTDG ASLAGTSSCS
       490        500        510        520        530        540
CLDSRLHLDG WEVGADDAET AEMIAHRTGG MKLSATVIFN PKSPTSLDSA VATQEAASEP
       550        560        570        580        590        600
VAEGMDGGPH KLSTGATNCL LHSCVCCGSC GDSREDVVER LREKCSPGGV IGASYAAGLA
       610        620        630        640        650        660
KASDRAPERQ EEAPPPSEDA SNGREPKAPT SDKCLPHTSG SQVDTASGLQ GEAGVAGQQE
       670        680        690        700        710        720
PEARELHAGS PSAHEAPQAL SGSSSSTAGS CSSDKMGPEA APAATHAAPQ ATREKIRSRF
       730        740        750        760        770        780
HGSHDLIHRL FVCISGVADQ LQTNYASDLR SILKTLFEVM ATKPETDDKE KLRKVTQTLR
       790        800        810        820        830        840
SAALEDCALC QETLSSSELA AKTRDGDFED PPEWVPDEAC GFCTACKAPF TVIRRKHHCR
       850        860        870        880
SCGKIFCSRC SSHSAPLPRY GQVKPVRVCT HCYMFHVTPF YSDKAGL         10         20         30         40         50         60
MMNRFRKWLY KPKRSDPQLL ARFYYADEEL NQVAAELDSL DGRKDPQRCT LLVSQFRSCQ
        70         80         90        100        110        120
DNVLNIINQI MDECIPQDRA PRDFCVKFPE EIRHDNLAGQ LWFGAECLAA GSIIMNRELE
       130        140        150        160        170        180
SMAMRPLAKE LTRSLEDVRG ALRDQALRDL NTYTEKMREA LRHFDVLFAE FELSYVSAMV
       190        200        210        220        230        240
PVKSPREYYV QQEVIVLFCE TVERALDFGY LTQDMIDDYE PALMFSIPRL AIVCGLVVYA
       250        260        270        280        290        300
DGPLNLDRKV EDMSELFRPF HTLLRKIRDL LQTLTEEELH TLERNLCISQ DVEFPIRADV
       310        320        330        340        350        360
QGPAALAPAL SAPLPPEGPL SAKAKDPDAE LACSMQYDDQ ELEQLSRMVH RAGDEMSSLL
       370        380        390        400        410        420
SPPIACQSPA HRPGAEGSPG GEASPGRPRL RSGSDEEERV FFMDDVEGTA EALARPESPA
       430        440        450        460        470        480
GPFGWAGSTW ADPQEKGQGG PGGAAGISLP ASEKEEDLSN NNLEAEGTDG ASLAGTSSCS
       490        500        510        520        530        540
CLDSRLHLDG WEVGADDAET AEMIAHRTGG MKLSATVIFN PKSPTSLDSA VATQEAASEP
       550        560        570        580        590        600
VAEGMDGGPH KLSTGATNCL LHSCVCCGSC GDSREDVVER LREKCSPGGV IGASYAAGLA
       610        620        630        640        650        660
KASDRAPERQ EEAPPPSEDA SNGREPKAPT SDKCLPHTSG SQVDTASGLQ GEAGVAGQQE
       670        680        690        700        710        720
PEARELHAGS PSAHEAPQAL SGSSSSTAGS CSSDKMGPEA APAATHAAPQ ATREKIRSRF
       730        740        750        760        770        780
HGSHDLIHRL FVCISGVADQ LQTNYASDLR SILKTLFEVM ATKPETDDKE KLRKVTQTLR
       790        800        810        820        830        840
SAALEDCALC QETLSSSELA AKTRDGDFED PPEWVPDEAC GFCTACKAPF TVIRRKHHCR
       850        860        870        880
SCGKIFCSRC SSHSAPLPRY GQVKPVRVCT HCYMFHVTPF YSDKAGL         10         20         30         40         50         60
MMNRFRKWLY KPKRSDPQLL ARFYYADEEL NQVAAELDSL DGRKDPQRCT LLVSQFRSCQ
        70         80         90        100        110        120
DNVLNIINQI MDECIPQDRA PRDFCVKFPE EIRHDNLAGQ LWFGAECLAA GSIIMNRELE
       130        140        150        160        170        180
SMAMRPLAKE LTRSLEDVRG ALRDQALRDL NTYTEKMREA LRHFDVLFAE FELSYVSAMV
       190        200        210        220        230        240
PVKSPREYYV QQEVIVLFCE TVERALDFGY LTQDMIDDYE PALMFSIPRL AIVCGLVVYA
       250        260        270        280        290        300
DGPLNLDRKV EDMSELFRPF HTLLRKIRDL LQTLTEEELH TLERNLCISQ DVEFPIRADV
       310        320        330        340        350        360
QGPAALAPAL SAPLPPEGPL SAKAKDPDAE LACSMQYDDQ ELEQLSRMVH RAGDEMSSLL
       370        380        390        400        410        420
SPPIACQSPA HRPGAEGSPG GEASPGRPRL RSGSDEEERV FFMDDVEGTA EALARPESPA
       430        440        450        460        470        480
GPFGWAGSTW ADPQEKGQGG PGGAAGISLP ASEKEEDLSN NNLEAEGTDG ASLAGTSSCS
       490        500        510        520        530        540
CLDSRLHLDG WEVGADDAET AEMIAHRTGG MKLSATVIFN PKSPTSLDSA VATQEAASEP
       550        560        570        580        590        600
VAEGMDGGPH KLSTGATNCL LHSCVCCGSC GDSREDVVER LREKCSPGGV IGASYAAGLA
       610        620        630        640        650        660
KASDRAPERQ EEAPPPSEDA SNGREPKAPT SDKCLPHTSG SQVDTASGLQ GEAGVAGQQE
       670        680        690        700        710        720
PEARELHAGS PSAHEAPQAL SGSSSSTAGS CSSDKMGPEA APAATHAAPQ ATREKIRSRF
       730        740        750        760        770        780
HGSHDLIHRL FVCISGVADQ LQTNYASDLR SILKTLFEVM ATKPETDDKE KLRKVTQTLR
       790        800        810        820        830        840
SAALEDCALC QETLSSSELA AKTRDGDFED PPEWVPDEAC GFCTACKAPF TVIRRKHHCR
       850        860        870        880
SCGKIFCSRC SSHSAPLPRY GQVKPVRVCT HCYMFHVTPF YSDKAGL         10         20         30         40         50         60
MMNRFRKWLY KPKRSDPQLL ARFYYADEEL NQVAAELDSL DGRKDPQRCT LLVSQFRSCQ
        70         80         90        100        110        120
DNVLNIINQI MDECIPQDRA PRDFCVKFPE EIRHDNLAGQ LWFGAECLAA GSIIMNRELE
       130        140        150        160        170        180
SMAMRPLAKE LTRSLEDVRG ALRDQALRDL NTYTEKMREA LRHFDVLFAE FELSYVSAMV
       190        200        210        220        230        240
PVKSPREYYV QQEVIVLFCE TVERALDFGY LTQDMIDDYE PALMFSIPRL AIVCGLVVYA
       250        260        270        280        290        300
DGPLNLDRKV EDMSELFRPF HTLLRKIRDL LQTLTEEELH TLERNLCISQ DVEFPIRADV
       310        320        330        340        350        360
QGPAALAPAL SAPLPPEGPL SAKAKDPDAE LACSMQYDDQ ELEQLSRMVH RAGDEMSSLL
       370        380        390        400        410        420
SPPIACQSPA HRPGAEGSPG GEASPGRPRL RSGSDEEERV FFMDDVEGTA EALARPESPA
       430        440        450        460        470        480
GPFGWAGSTW ADPQEKGQGG PGGAAGISLP ASEKEEDLSN NNLEAEGTDG ASLAGTSSCS
       490        500        510        520        530        540
CLDSRLHLDG WEVGADDAET AEMIAHRTGG MKLSATVIFN PKSPTSLDSA VATQEAASEP
       550        560        570        580        590        600
VAEGMDGGPH KLSTGATNCL LHSCVCCGSC GDSREDVVER LREKCSPGGV IGASYAAGLA
       610        620        630        640        650        660
KASDRAPERQ EEAPPPSEDA SNGREPKAPT SDKCLPHTSG SQVDTASGLQ GEAGVAGQQE
       670        680        690        700        710        720
PEARELHAGS PSAHEAPQAL SGSSSSTAGS CSSDKMGPEA APAATHAAPQ ATREKIRSRF
       730        740        750        760        770        780
HGSHDLIHRL FVCISGVADQ LQTNYASDLR SILKTLFEVM ATKPETDDKE KLRKVTQTLR
       790        800        810        820        830        840
SAALEDCALC QETLSSSELA AKTRDGDFED PPEWVPDEAC GFCTACKAPF TVIRRKHHCR
       850        860        870        880
SCGKIFCSRC SSHSAPLPRY GQVKPVRVCT HCYMFHVTPF YSDKAGL         10         20         30         40         50         60
MMNRFRKWLY KPKRSDPQLL ARFYYADEEL NQVAAELDSL DGRKDPQRCT LLVSQFRSCQ
        70         80         90        100        110        120
DNVLNIINQI MDECIPQDRA PRDFCVKFPE EIRHDNLAGQ LWFGAECLAA GSIIMNRELE
       130        140        150        160        170        180
SMAMRPLAKE LTRSLEDVRG ALRDQALRDL NTYTEKMREA LRHFDVLFAE FELSYVSAMV
       190        200        210        220        230        240
PVKSPREYYV QQEVIVLFCE TVERALDFGY LTQDMIDDYE PALMFSIPRL AIVCGLVVYA
       250        260        270        280        290        300
DGPLNLDRKV EDMSELFRPF HTLLRKIRDL LQTLTEEELH TLERNLCISQ DVEFPIRADV
       310        320        330        340        350        360
QGPAALAPAL SAPLPPEGPL SAKAKDPDAE LACSMQYDDQ ELEQLSRMVH RAGDEMSSLL
       370        380        390        400        410        420
SPPIACQSPA HRPGAEGSPG GEASPGRPRL RSGSDEEERV FFMDDVEGTA EALARPESPA
       430        440        450        460        470        480
GPFGWAGSTW ADPQEKGQGG PGGAAGISLP ASEKEEDLSN NNLEAEGTDG ASLAGTSSCS
       490        500        510        520        530        540
CLDSRLHLDG WEVGADDAET AEMIAHRTGG MKLSATVIFN PKSPTSLDSA VATQEAASEP
       550        560        570        580        590        600
VAEGMDGGPH KLSTGATNCL LHSCVCCGSC GDSREDVVER LREKCSPGGV IGASYAAGLA
       610        620        630        640        650        660
KASDRAPERQ EEAPPPSEDA SNGREPKAPT SDKCLPHTSG SQVDTASGLQ GEAGVAGQQE
       670        680        690        700        710        720
PEARELHAGS PSAHEAPQAL SGSSSSTAGS CSSDKMGPEA APAATHAAPQ ATREKIRSRF
       730        740        750        760        770        780
HGSHDLIHRL FVCISGVADQ LQTNYASDLR SILKTLFEVM ATKPETDDKE KLRKVTQTLR
       790        800        810        820        830        840
SAALEDCALC QETLSSSELA AKTRDGDFED PPEWVPDEAC GFCTACKAPF TVIRRKHHCR
       850        860        870        880
SCGKIFCSRC SSHSAPLPRY GQVKPVRVCT HCYMFHVTPF YSDKAGL         10         20         30         40         50         60
MMNRFRKWLY KPKRSDPQLL ARFYYADEEL NQVAAELDSL DGRKDPQRCT LLVSQFRSCQ
        70         80         90        100        110        120
DNVLNIINQI MDECIPQDRA PRDFCVKFPE EIRHDNLAGQ LWFGAECLAA GSIIMNRELE
       130        140        150        160        170        180
SMAMRPLAKE LTRSLEDVRG ALRDQALRDL NTYTEKMREA LRHFDVLFAE FELSYVSAMV
       190        200        210        220        230        240
PVKSPREYYV QQEVIVLFCE TVERALDFGY LTQDMIDDYE PALMFSIPRL AIVCGLVVYA
       250        260        270        280        290        300
DGPLNLDRKV EDMSELFRPF HTLLRKIRDL LQTLTEEELH TLERNLCISQ DVEFPIRADV
       310        320        330        340        350        360
QGPAALAPAL SAPLPPEGPL SAKAKDPDAE LACSMQYDDQ ELEQLSRMVH RAGDEMSSLL
       370        380        390        400        410        420
SPPIACQSPA HRPGAEGSPG GEASPGRPRL RSGSDEEERV FFMDDVEGTA EALARPESPA
       430        440        450        460        470        480
GPFGWAGSTW ADPQEKGQGG PGGAAGISLP ASEKEEDLSN NNLEAEGTDG ASLAGTSSCS
       490        500        510        520        530        540
CLDSRLHLDG WEVGADDAET AEMIAHRTGG MKLSATVIFN PKSPTSLDSA VATQEAASEP
       550        560        570        580        590        600
VAEGMDGGPH KLSTGATNCL LHSCVCCGSC GDSREDVVER LREKCSPGGV IGASYAAGLA
       610        620        630        640        650        660
KASDRAPERQ EEAPPPSEDA SNGREPKAPT SDKCLPHTSG SQVDTASGLQ GEAGVAGQQE
       670        680        690        700        710        720
PEARELHAGS PSAHEAPQAL SGSSSSTAGS CSSDKMGPEA APAATHAAPQ ATREKIRSRF
       730        740        750        760        770        780
HGSHDLIHRL FVCISGVADQ LQTNYASDLR SILKTLFEVM ATKPETDDKE KLRKVTQTLR
       790        800        810        820        830        840
SAALEDCALC QETLSSSELA AKTRDGDFED PPEWVPDEAC GFCTACKAPF TVIRRKHHCR
       850        860        870        880
SCGKIFCSRC SSHSAPLPRY GQVKPVRVCT HCYMFHVTPF YSDKAGL

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q9HCC9-1-unknown	MMNRFR...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9HCC9-1-unknown	MMNRFR...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt80030
Q9HCC9-1-unknown	MMNRFR...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt80034
Q9HCC9-71-unknown	MDECIP...	71	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt80031
Q9HCC9-71-unknown	MDECIP...	71	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt80032
Q9HCC9-71-unknown	MDECIP...	71	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt80036
Q9HCC9-71-unknown	MDECIP...	71	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt104755
Q9HCC9-71-unknown	MDECIP...	71	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt104756
Q9HCC9-71-unknown	MDECIP...	71	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt104757
Q9HCC9-115-unknown	MNRELE...	115	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt80033
Q9HCC9-115-unknown	MNRELE...	115	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt104860
Q9HCC9-115-unknown	MNRELE...	115	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt104863
Q9HCC9-115-unknown	MNRELE...	115	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt104864
Q9HCC9-115-unknown	MNRELE...	115	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt104861
Q9HCC9-115-unknown	MNRELE...	115	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt104862
Q9HCC9-115-unknown	MNRELE...	115	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt104865

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...RLAIVC	233	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt75654
...RLAIVC	233	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt91757
...RLAIVC	233	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt91758
...RLAIVC	233	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt91756
...DKAGL	887	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...DKAGL	887	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt75651
...DKAGL	887	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt75650
...DKAGL	887	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt75649
...DKAGL	887	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt75648

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)