TopFIND 4.0

Q9HD40: O-phosphoseryl-tRNA(Sec) selenium transferase

General Information

Protein names
- O-phosphoseryl-tRNA(Sec) selenium transferase
- 2.9.1.2 {ECO:0000269|PubMed:17142313}
- Liver-pancreas antigen
- LP
- SLA-p35
- SLA/LP autoantigen
- Selenocysteine synthase
- Sec synthase
- Selenocysteinyl-tRNA(Sec) synthase
- Sep-tRNA:Sec-tRNA synthase
- SepSecS
- Soluble liver antigen
- SLA
- UGA suppressor tRNA-associated protein
- tRNA(Ser/Sec)-associated antigenic protein
Gene names SEPSECS
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q9HD40

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MNRESFAAGE RLVSPAYVRQ GCEARRSHEH LIRLLLEKGK CPENGWDEST LELFLHELAI 
        70         80         90        100        110        120 
MDSNNFLGNC GVGEREGRVA SALVARRHYR FIHGIGRSGD ISAVQPKAAG SSLLNKITNS 
       130        140        150        160        170        180 
LVLDIIKLAG VHTVANCFVV PMATGMSLTL CFLTLRHKRP KAKYIIWPRI DQKSCFKSMI 
       190        200        210        220        230        240 
TAGFEPVVIE NVLEGDELRT DLKAVEAKVQ ELGPDCILCI HSTTSCFAPR VPDRLEELAV 
       250        260        270        280        290        300 
ICANYDIPHI VNNAYGVQSS KCMHLIQQGA RVGRIDAFVQ SLDKNFMVPV GGAIIAGFND 
       310        320        330        340        350        360 
SFIQEISKMY PGRASASPSL DVLITLLSLG SNGYKKLLKE RKEMFSYLSN QIKKLSEAYN 
       370        380        390        400        410        420 
ERLLHTPHNP ISLAMTLKTL DEHRDKAVTQ LGSMLFTRQV SGARVVPLGS MQTVSGYTFR 
       430        440        450        460        470        480 
GFMSHTNNYP CAYLNAASAI GMKMQDVDLF IKRLDRCLKA VRKERSKESD DNYDKTEDVD 
       490        500    
IEEMALKLDN VLLDTYQDAS S

Isoforms

- Isoform 2 of O-phosphoseryl-tRNA(Sec) selenium transferase - Isoform 3 of O-phosphoseryl-tRNA(Sec) selenium transferase

Sequence View

        10         20         30         40         50         60 
MNRESFAAGE RLVSPAYVRQ GCEARRSHEH LIRLLLEKGK CPENGWDEST LELFLHELAI 
        70         80         90        100        110        120 
MDSNNFLGNC GVGEREGRVA SALVARRHYR FIHGIGRSGD ISAVQPKAAG SSLLNKITNS 
       130        140        150        160        170        180 
LVLDIIKLAG VHTVANCFVV PMATGMSLTL CFLTLRHKRP KAKYIIWPRI DQKSCFKSMI 
       190        200        210        220        230        240 
TAGFEPVVIE NVLEGDELRT DLKAVEAKVQ ELGPDCILCI HSTTSCFAPR VPDRLEELAV 
       250        260        270        280        290        300 
ICANYDIPHI VNNAYGVQSS KCMHLIQQGA RVGRIDAFVQ SLDKNFMVPV GGAIIAGFND 
       310        320        330        340        350        360 
SFIQEISKMY PGRASASPSL DVLITLLSLG SNGYKKLLKE RKEMFSYLSN QIKKLSEAYN 
       370        380        390        400        410        420 
ERLLHTPHNP ISLAMTLKTL DEHRDKAVTQ LGSMLFTRQV SGARVVPLGS MQTVSGYTFR 
       430        440        450        460        470        480 
GFMSHTNNYP CAYLNAASAI GMKMQDVDLF IKRLDRCLKA VRKERSKESD DNYDKTEDVD 
       490        500    
IEEMALKLDN VLLDTYQDAS S         10         20         30         40         50         60 
MNRESFAAGE RLVSPAYVRQ GCEARRSHEH LIRLLLEKGK CPENGWDEST LELFLHELAI 
        70         80         90        100        110        120 
MDSNNFLGNC GVGEREGRVA SALVARRHYR FIHGIGRSGD ISAVQPKAAG SSLLNKITNS 
       130        140        150        160        170        180 
LVLDIIKLAG VHTVANCFVV PMATGMSLTL CFLTLRHKRP KAKYIIWPRI DQKSCFKSMI 
       190        200        210        220        230        240 
TAGFEPVVIE NVLEGDELRT DLKAVEAKVQ ELGPDCILCI HSTTSCFAPR VPDRLEELAV 
       250        260        270        280        290        300 
ICANYDIPHI VNNAYGVQSS KCMHLIQQGA RVGRIDAFVQ SLDKNFMVPV GGAIIAGFND 
       310        320        330        340        350        360 
SFIQEISKMY PGRASASPSL DVLITLLSLG SNGYKKLLKE RKEMFSYLSN QIKKLSEAYN 
       370        380        390        400        410        420 
ERLLHTPHNP ISLAMTLKTL DEHRDKAVTQ LGSMLFTRQV SGARVVPLGS MQTVSGYTFR 
       430        440        450        460        470        480 
GFMSHTNNYP CAYLNAASAI GMKMQDVDLF IKRLDRCLKA VRKERSKESD DNYDKTEDVD 
       490        500    
IEEMALKLDN VLLDTYQDAS S



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9HD40-1-unknown MNRESF... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9HD40-1-unknown MNRESF... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt90397

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...QDASS 501 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...QDASS 501 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt86016

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)