TopFIND 4.0

Q9JHI8: NADPH oxidase 4

General Information

Protein names
- NADPH oxidase 4
- 1.6.3.-
- Kidney oxidase-1
- KOX-1
- Kidney superoxide-producing NADPH oxidase
- Renal NAD(P)H-oxidase
- Superoxide-generating NADPH oxidase 4
Gene names Nox4
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q9JHI8

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAVSWRSWLA NEGVKHLCLL IWLSLNVLLF WKTFLLYNQG PEYYYIHQML GLGLCLSRAS 
        70         80         90        100        110        120 
ASVLNLNCSL ILLPMCRTVL AYLRGSQKVP SRRTRRLLDK SKTLHITCGV TICIFSGVHV 
       130        140        150        160        170        180 
AAHLVNALNF SVNYSEDFLE LNAARYQNED PRKLLFTTIP GLTGVCMVVV LFLMVTASTY 
       190        200        210        220        230        240 
AIRVSNYDIF WYTHNLFFVF YMLLLLHVSG GLLKYQTNVD THPPGCISLN QTSSQNMSIP 
       250        260        270        280        290        300 
DYVSEHFHGS LPRGFSKLED RYQKTLVKIC LEEPKFQAHF PQTWIWISGP LCLYCAERLY 
       310        320        330        340        350        360 
RCIRSNKPVT IISVINHPSD VMELRMIKEN FKARPGQYII LHCPSVSALE NHPFTLTMCP 
       370        380        390        400        410        420 
TETKATFGVH FKVVGDWTER FRDLLLPPSS QDSEILPFIH SRNYPKLYID GPFGSPFEES 
       430        440        450        460        470        480 
LNYEVSLCVA GGIGVTPFAS ILNTLLDDWK PYKLRRLYFI WVCRDIQSFQ WFADLLCVLH 
       490        500        510        520        530        540 
NKFWQENRPD FVNIQLYLSQ TDGIQKIIGE KYHTLNSRLF IGRPRWKLLF DEIAKCNRGK 
       550        560        570    
TVGVFCCGPS SISKTLHSLS NRNNSYGTKF EYNKESFS

Isoforms

- Isoform 2 of NADPH oxidase 4 - Isoform 3 of NADPH oxidase 4 - Isoform 4 of NADPH oxidase 4

Sequence View

        10         20         30         40         50         60 
MAVSWRSWLA NEGVKHLCLL IWLSLNVLLF WKTFLLYNQG PEYYYIHQML GLGLCLSRAS 
        70         80         90        100        110        120 
ASVLNLNCSL ILLPMCRTVL AYLRGSQKVP SRRTRRLLDK SKTLHITCGV TICIFSGVHV 
       130        140        150        160        170        180 
AAHLVNALNF SVNYSEDFLE LNAARYQNED PRKLLFTTIP GLTGVCMVVV LFLMVTASTY 
       190        200        210        220        230        240 
AIRVSNYDIF WYTHNLFFVF YMLLLLHVSG GLLKYQTNVD THPPGCISLN QTSSQNMSIP 
       250        260        270        280        290        300 
DYVSEHFHGS LPRGFSKLED RYQKTLVKIC LEEPKFQAHF PQTWIWISGP LCLYCAERLY 
       310        320        330        340        350        360 
RCIRSNKPVT IISVINHPSD VMELRMIKEN FKARPGQYII LHCPSVSALE NHPFTLTMCP 
       370        380        390        400        410        420 
TETKATFGVH FKVVGDWTER FRDLLLPPSS QDSEILPFIH SRNYPKLYID GPFGSPFEES 
       430        440        450        460        470        480 
LNYEVSLCVA GGIGVTPFAS ILNTLLDDWK PYKLRRLYFI WVCRDIQSFQ WFADLLCVLH 
       490        500        510        520        530        540 
NKFWQENRPD FVNIQLYLSQ TDGIQKIIGE KYHTLNSRLF IGRPRWKLLF DEIAKCNRGK 
       550        560        570    
TVGVFCCGPS SISKTLHSLS NRNNSYGTKF EYNKESFS         10         20         30         40         50         60 
MAVSWRSWLA NEGVKHLCLL IWLSLNVLLF WKTFLLYNQG PEYYYIHQML GLGLCLSRAS 
        70         80         90        100        110        120 
ASVLNLNCSL ILLPMCRTVL AYLRGSQKVP SRRTRRLLDK SKTLHITCGV TICIFSGVHV 
       130        140        150        160        170        180 
AAHLVNALNF SVNYSEDFLE LNAARYQNED PRKLLFTTIP GLTGVCMVVV LFLMVTASTY 
       190        200        210        220        230        240 
AIRVSNYDIF WYTHNLFFVF YMLLLLHVSG GLLKYQTNVD THPPGCISLN QTSSQNMSIP 
       250        260        270        280        290        300 
DYVSEHFHGS LPRGFSKLED RYQKTLVKIC LEEPKFQAHF PQTWIWISGP LCLYCAERLY 
       310        320        330        340        350        360 
RCIRSNKPVT IISVINHPSD VMELRMIKEN FKARPGQYII LHCPSVSALE NHPFTLTMCP 
       370        380        390        400        410        420 
TETKATFGVH FKVVGDWTER FRDLLLPPSS QDSEILPFIH SRNYPKLYID GPFGSPFEES 
       430        440        450        460        470        480 
LNYEVSLCVA GGIGVTPFAS ILNTLLDDWK PYKLRRLYFI WVCRDIQSFQ WFADLLCVLH 
       490        500        510        520        530        540 
NKFWQENRPD FVNIQLYLSQ TDGIQKIIGE KYHTLNSRLF IGRPRWKLLF DEIAKCNRGK 
       550        560        570    
TVGVFCCGPS SISKTLHSLS NRNNSYGTKF EYNKESFS         10         20         30         40         50         60 
MAVSWRSWLA NEGVKHLCLL IWLSLNVLLF WKTFLLYNQG PEYYYIHQML GLGLCLSRAS 
        70         80         90        100        110        120 
ASVLNLNCSL ILLPMCRTVL AYLRGSQKVP SRRTRRLLDK SKTLHITCGV TICIFSGVHV 
       130        140        150        160        170        180 
AAHLVNALNF SVNYSEDFLE LNAARYQNED PRKLLFTTIP GLTGVCMVVV LFLMVTASTY 
       190        200        210        220        230        240 
AIRVSNYDIF WYTHNLFFVF YMLLLLHVSG GLLKYQTNVD THPPGCISLN QTSSQNMSIP 
       250        260        270        280        290        300 
DYVSEHFHGS LPRGFSKLED RYQKTLVKIC LEEPKFQAHF PQTWIWISGP LCLYCAERLY 
       310        320        330        340        350        360 
RCIRSNKPVT IISVINHPSD VMELRMIKEN FKARPGQYII LHCPSVSALE NHPFTLTMCP 
       370        380        390        400        410        420 
TETKATFGVH FKVVGDWTER FRDLLLPPSS QDSEILPFIH SRNYPKLYID GPFGSPFEES 
       430        440        450        460        470        480 
LNYEVSLCVA GGIGVTPFAS ILNTLLDDWK PYKLRRLYFI WVCRDIQSFQ WFADLLCVLH 
       490        500        510        520        530        540 
NKFWQENRPD FVNIQLYLSQ TDGIQKIIGE KYHTLNSRLF IGRPRWKLLF DEIAKCNRGK 
       550        560        570    
TVGVFCCGPS SISKTLHSLS NRNNSYGTKF EYNKESFS



Filter Information:


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Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...KESFS 578 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...KESFS 578 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt78701

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)