TopFIND 4.0

Q9JHX4: Caspase-8 {ECO:0000303|Ref.2, ECO:0000305}

General Information

Protein names
- Caspase-8 {ECO:0000303|Ref.2, ECO:0000305}
- CASP-8
- 3.4.22.61
- Caspase-8 subunit p18
- Caspase-8 subunit p10
Gene names Casp8 {ECO:0000312|RGD:620945}
Organism Rattus norvegicus
Protease Family
Protease ID C14.009
Chromosome location
UniProt ID Q9JHX4

2

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MDFHSCLYDI AERLGNEELA ALKFLCLDHI PQKKQESIND VLVLFQRLQE EGMLEEDNLS 
        70         80         90        100        110        120 
FLKELLFHIS RRDLLSRVLK SSPEEMVREL QVLGKAQVSA YRVMLFKLSE DMDKEDLKSF 
       130        140        150        160        170        180 
KFLLITEIPK CKLQDNSSLL DIFVEMEKRT ILAENNLVTL KSICFRVNRS LLGRIDDYER 
       190        200        210        220        230        240 
SSTERRMSTE GGEELPVSVL DEVTIKMQDM WDSPGEQESE SLNSDNVYQM KSKPRGYCLI 
       250        260        270        280        290        300 
FNNNNFSKAR EDIPKLSNMR DRKGTNYDEE ALSKTFKELH FEIVSFSDCT ASQIHEVLVS 
       310        320        330        340        350        360 
YQSKDHKGKD CFICCILSHG DKGIVYGTDG KEASIYELTS YFTGSKCPSL AGKPKIFFIQ 
       370        380        390        400        410        420 
ACQGNNFQKA VPVPDETGLE QEHVLEEDSS SYKNYIPDEA DFLLGMATVK NCVSYRDPTR 
       430        440        450        460        470        480 
GTWYIQSLCQ SLRERCPRGE DILSILTGVN YDVSNKDNPR NMGKQMPQPI FTLRKKLFFP 
   
PN

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9JHX4-219-unknown SESLNS... 219 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9JHX4-389-unknown SSSYKN... 389 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...PDETGL 378 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...FFPPN 482 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)