Q9JIM3: DNA excision repair protein ERCC-6-like 2
| Protein names | - DNA excision repair protein ERCC-6-like 2 - 3.6.4.- - DNA repair and recombination protein RAD26-like |
|---|---|
| Gene names | Ercc6l2 |
| Organism | Mus musculus |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | Q9JIM3 |
1
N-termini
2
C-termini
0
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MDISAPQSRA DSRKDRWCPG ERCLAPSLDN KKLCEASIKS ITVDGNGKPF AVVLYPDFQE
70 80 90 100 110 120
KTIPLQRLQE VKSTKDYSRS LIFDDKDLEK PYFPDRKIPS LASAFQLSED GDSIPYTINR
130 140 150 160 170 180
YLRDYQREGA QFLYRHYIEG RGCILGDDMG LGKTIQVISF LAAVLHKKGT REDIENNMPE
190 200 210 220 230 240
FLLKSMKKKP PSTAKKMFLI VAPLSVLYNW KDELDTWGYF RVTVLHGSKK DNELLRLKQR
250 260 270 280 290 300
KCEIALTTYE TLRLCLEELN SLEWSAIIVD EAHRIKNPKA RVTEVMKAVK CKVRIGLTGT
310 320 330 340 350 360
VLQNNMKELW CVMDWAVPGL LGSRIHFKKQ FSDPVEHGQR HTATKRELAT GRKAMHRLAK
370 380 390 400 410 420
KMSGWFLRRT KTLIKGQLPK KEDRMVYCSL TDFQKAVYQT VLETEDVALI LTSSQPCTCG
430 440 450 460 470 480
SGQKRRKCCY KTNSRGDTVR TLCLSYLTVL QKVANHVALL QAASTSKHQE TVIKRICDRV
490 500 510 520 530 540
FSRFPDFVQK SKDAAFETLS DPKYSGKMKV LQQLLNHFRK QRDKVLLFSF STKLLDVLQQ
550 560 570 580 590 600
YCMASGLDYR RLDGSTKSEE RLKIVKEFNS SQDVNICLVS TMAGGLGLNF VGANVVILFD
610 620 630 640 650 660
PTWNPANDLQ AVDRAYRIGQ CRDVKVLRLI SLGTVEEIMY LRQVYKQQLH CVVVGSENAK
670 680 690 700 710 720
RYFEAVQGSK EHRGELFGVH NLFKLRSQGS CLTRDILERE GQVEAGIMTA TTWLKGEPSA
730 740 750 760 770 780
QELETPRDPD CQEPTDVCEL YSDISDEESV GHSLGKTDKH KFSDTSRTPG FPAQLTLLQC
790 800 810 820 830 840
GFSKLFEAKY KSDQDGDGNP VPSDGSSDEQ PMCLSAEARQ AARQKTWDSV CTSEHQKSDN
850 860 870 880 890 900
IQTPDEKCVS DKSEKTLEQN VSSESDDETK DHRTAGHHCM GQGDTESEDS DVIFPTQYPT
910 920 930 940 950 960
QRIPKNHIRF KLLLGESEDS EAENPVKVNH GDDRQNSGRG NGPVPNLLCL ENMTSKSVRK
970 980 990 1000 1010 1020
RKGTDDISDE SDDIDMFPKS RIRKQRATTS LKFKRKKENK RKLDNSPVTA KEANQVCAAD
1030 1040 1050 1060 1070 1080
GDRSSQVIED FSSSDDNLSL SHLSFTKLSH RAETVKDKIS LSPKLPGPDK KNNTFISRKP
1090 1100 1110 1120 1130 1140
PSFLNEGVIS QEQICNSMDK ILDGVQEVAY IHSNQNVIGS SRAENHMSRW ATRDVFELKQ
1150 1160 1170 1180 1190 1200
FSQLPANVAV CSSKTYKTQV KANIVSPTEK DQPPSDGGIS SPLYVSHPVV QKKKDVYRTN
1210 1220 1230 1240 1250 1260
HTTFIIGETP RGIRRKQFEE MASYYKLPVK EFAEQVTRAT SEERQKMLRD FYSLQHPEVK
1270 1280 1290 1300 1310 1320
EFFVNSASEL IKSVHKKEER VRNKSKEKES LLKENPSNDS TLSCYDSTNK MSQVYNRKIC
1330 1340 1350 1360 1370 1380
EGKSVRSQNH VFHREDTFSS DAEINKSPVS FTEELHSERK DHTPKDTTTV FCPNSNSEAL
1390 1400 1410 1420 1430 1440
EAELGNSPGR QWDLTGACGS RNRPLFKLRN KRVENPGSEN TPEDGLLGDT SILNDLFKSH
1450 1460 1470 1480 1490 1500
GEGPTQLPKN VLSGPVAKAK QKPKDFWDIL NEQNDDSLSK LTDLAVIETL CTKAPSTSAS
1510 1520 1530
KRKDELEASL WKANEKFLWK TLSSDVDDES ISNTERE
Isoforms
- Isoform 2 of DNA excision repair protein ERCC-6-like 2 - Isoform 3 of DNA excision repair protein ERCC-6-like 2 - Isoform 4 of DNA excision repair protein ERCC-6-like 2Sequence View
10 20 30 40 50 60
MDISAPQSRA DSRKDRWCPG ERCLAPSLDN KKLCEASIKS ITVDGNGKPF AVVLYPDFQE
70 80 90 100 110 120
KTIPLQRLQE VKSTKDYSRS LIFDDKDLEK PYFPDRKIPS LASAFQLSED GDSIPYTINR
130 140 150 160 170 180
YLRDYQREGA QFLYRHYIEG RGCILGDDMG LGKTIQVISF LAAVLHKKGT REDIENNMPE
190 200 210 220 230 240
FLLKSMKKKP PSTAKKMFLI VAPLSVLYNW KDELDTWGYF RVTVLHGSKK DNELLRLKQR
250 260 270 280 290 300
KCEIALTTYE TLRLCLEELN SLEWSAIIVD EAHRIKNPKA RVTEVMKAVK CKVRIGLTGT
310 320 330 340 350 360
VLQNNMKELW CVMDWAVPGL LGSRIHFKKQ FSDPVEHGQR HTATKRELAT GRKAMHRLAK
370 380 390 400 410 420
KMSGWFLRRT KTLIKGQLPK KEDRMVYCSL TDFQKAVYQT VLETEDVALI LTSSQPCTCG
430 440 450 460 470 480
SGQKRRKCCY KTNSRGDTVR TLCLSYLTVL QKVANHVALL QAASTSKHQE TVIKRICDRV
490 500 510 520 530 540
FSRFPDFVQK SKDAAFETLS DPKYSGKMKV LQQLLNHFRK QRDKVLLFSF STKLLDVLQQ
550 560 570 580 590 600
YCMASGLDYR RLDGSTKSEE RLKIVKEFNS SQDVNICLVS TMAGGLGLNF VGANVVILFD
610 620 630 640 650 660
PTWNPANDLQ AVDRAYRIGQ CRDVKVLRLI SLGTVEEIMY LRQVYKQQLH CVVVGSENAK
670 680 690 700 710 720
RYFEAVQGSK EHRGELFGVH NLFKLRSQGS CLTRDILERE GQVEAGIMTA TTWLKGEPSA
730 740 750 760 770 780
QELETPRDPD CQEPTDVCEL YSDISDEESV GHSLGKTDKH KFSDTSRTPG FPAQLTLLQC
790 800 810 820 830 840
GFSKLFEAKY KSDQDGDGNP VPSDGSSDEQ PMCLSAEARQ AARQKTWDSV CTSEHQKSDN
850 860 870 880 890 900
IQTPDEKCVS DKSEKTLEQN VSSESDDETK DHRTAGHHCM GQGDTESEDS DVIFPTQYPT
910 920 930 940 950 960
QRIPKNHIRF KLLLGESEDS EAENPVKVNH GDDRQNSGRG NGPVPNLLCL ENMTSKSVRK
970 980 990 1000 1010 1020
RKGTDDISDE SDDIDMFPKS RIRKQRATTS LKFKRKKENK RKLDNSPVTA KEANQVCAAD
1030 1040 1050 1060 1070 1080
GDRSSQVIED FSSSDDNLSL SHLSFTKLSH RAETVKDKIS LSPKLPGPDK KNNTFISRKP
1090 1100 1110 1120 1130 1140
PSFLNEGVIS QEQICNSMDK ILDGVQEVAY IHSNQNVIGS SRAENHMSRW ATRDVFELKQ
1150 1160 1170 1180 1190 1200
FSQLPANVAV CSSKTYKTQV KANIVSPTEK DQPPSDGGIS SPLYVSHPVV QKKKDVYRTN
1210 1220 1230 1240 1250 1260
HTTFIIGETP RGIRRKQFEE MASYYKLPVK EFAEQVTRAT SEERQKMLRD FYSLQHPEVK
1270 1280 1290 1300 1310 1320
EFFVNSASEL IKSVHKKEER VRNKSKEKES LLKENPSNDS TLSCYDSTNK MSQVYNRKIC
1330 1340 1350 1360 1370 1380
EGKSVRSQNH VFHREDTFSS DAEINKSPVS FTEELHSERK DHTPKDTTTV FCPNSNSEAL
1390 1400 1410 1420 1430 1440
EAELGNSPGR QWDLTGACGS RNRPLFKLRN KRVENPGSEN TPEDGLLGDT SILNDLFKSH
1450 1460 1470 1480 1490 1500
GEGPTQLPKN VLSGPVAKAK QKPKDFWDIL NEQNDDSLSK LTDLAVIETL CTKAPSTSAS
1510 1520 1530
KRKDELEASL WKANEKFLWK TLSSDVDDES ISNTERE
10 20 30 40 50 60
MDISAPQSRA DSRKDRWCPG ERCLAPSLDN KKLCEASIKS ITVDGNGKPF AVVLYPDFQE
70 80 90 100 110 120
KTIPLQRLQE VKSTKDYSRS LIFDDKDLEK PYFPDRKIPS LASAFQLSED GDSIPYTINR
130 140 150 160 170 180
YLRDYQREGA QFLYRHYIEG RGCILGDDMG LGKTIQVISF LAAVLHKKGT REDIENNMPE
190 200 210 220 230 240
FLLKSMKKKP PSTAKKMFLI VAPLSVLYNW KDELDTWGYF RVTVLHGSKK DNELLRLKQR
250 260 270 280 290 300
KCEIALTTYE TLRLCLEELN SLEWSAIIVD EAHRIKNPKA RVTEVMKAVK CKVRIGLTGT
310 320 330 340 350 360
VLQNNMKELW CVMDWAVPGL LGSRIHFKKQ FSDPVEHGQR HTATKRELAT GRKAMHRLAK
370 380 390 400 410 420
KMSGWFLRRT KTLIKGQLPK KEDRMVYCSL TDFQKAVYQT VLETEDVALI LTSSQPCTCG
430 440 450 460 470 480
SGQKRRKCCY KTNSRGDTVR TLCLSYLTVL QKVANHVALL QAASTSKHQE TVIKRICDRV
490 500 510 520 530 540
FSRFPDFVQK SKDAAFETLS DPKYSGKMKV LQQLLNHFRK QRDKVLLFSF STKLLDVLQQ
550 560 570 580 590 600
YCMASGLDYR RLDGSTKSEE RLKIVKEFNS SQDVNICLVS TMAGGLGLNF VGANVVILFD
610 620 630 640 650 660
PTWNPANDLQ AVDRAYRIGQ CRDVKVLRLI SLGTVEEIMY LRQVYKQQLH CVVVGSENAK
670 680 690 700 710 720
RYFEAVQGSK EHRGELFGVH NLFKLRSQGS CLTRDILERE GQVEAGIMTA TTWLKGEPSA
730 740 750 760 770 780
QELETPRDPD CQEPTDVCEL YSDISDEESV GHSLGKTDKH KFSDTSRTPG FPAQLTLLQC
790 800 810 820 830 840
GFSKLFEAKY KSDQDGDGNP VPSDGSSDEQ PMCLSAEARQ AARQKTWDSV CTSEHQKSDN
850 860 870 880 890 900
IQTPDEKCVS DKSEKTLEQN VSSESDDETK DHRTAGHHCM GQGDTESEDS DVIFPTQYPT
910 920 930 940 950 960
QRIPKNHIRF KLLLGESEDS EAENPVKVNH GDDRQNSGRG NGPVPNLLCL ENMTSKSVRK
970 980 990 1000 1010 1020
RKGTDDISDE SDDIDMFPKS RIRKQRATTS LKFKRKKENK RKLDNSPVTA KEANQVCAAD
1030 1040 1050 1060 1070 1080
GDRSSQVIED FSSSDDNLSL SHLSFTKLSH RAETVKDKIS LSPKLPGPDK KNNTFISRKP
1090 1100 1110 1120 1130 1140
PSFLNEGVIS QEQICNSMDK ILDGVQEVAY IHSNQNVIGS SRAENHMSRW ATRDVFELKQ
1150 1160 1170 1180 1190 1200
FSQLPANVAV CSSKTYKTQV KANIVSPTEK DQPPSDGGIS SPLYVSHPVV QKKKDVYRTN
1210 1220 1230 1240 1250 1260
HTTFIIGETP RGIRRKQFEE MASYYKLPVK EFAEQVTRAT SEERQKMLRD FYSLQHPEVK
1270 1280 1290 1300 1310 1320
EFFVNSASEL IKSVHKKEER VRNKSKEKES LLKENPSNDS TLSCYDSTNK MSQVYNRKIC
1330 1340 1350 1360 1370 1380
EGKSVRSQNH VFHREDTFSS DAEINKSPVS FTEELHSERK DHTPKDTTTV FCPNSNSEAL
1390 1400 1410 1420 1430 1440
EAELGNSPGR QWDLTGACGS RNRPLFKLRN KRVENPGSEN TPEDGLLGDT SILNDLFKSH
1450 1460 1470 1480 1490 1500
GEGPTQLPKN VLSGPVAKAK QKPKDFWDIL NEQNDDSLSK LTDLAVIETL CTKAPSTSAS
1510 1520 1530
KRKDELEASL WKANEKFLWK TLSSDVDDES ISNTERE
10 20 30 40 50 60
MDISAPQSRA DSRKDRWCPG ERCLAPSLDN KKLCEASIKS ITVDGNGKPF AVVLYPDFQE
70 80 90 100 110 120
KTIPLQRLQE VKSTKDYSRS LIFDDKDLEK PYFPDRKIPS LASAFQLSED GDSIPYTINR
130 140 150 160 170 180
YLRDYQREGA QFLYRHYIEG RGCILGDDMG LGKTIQVISF LAAVLHKKGT REDIENNMPE
190 200 210 220 230 240
FLLKSMKKKP PSTAKKMFLI VAPLSVLYNW KDELDTWGYF RVTVLHGSKK DNELLRLKQR
250 260 270 280 290 300
KCEIALTTYE TLRLCLEELN SLEWSAIIVD EAHRIKNPKA RVTEVMKAVK CKVRIGLTGT
310 320 330 340 350 360
VLQNNMKELW CVMDWAVPGL LGSRIHFKKQ FSDPVEHGQR HTATKRELAT GRKAMHRLAK
370 380 390 400 410 420
KMSGWFLRRT KTLIKGQLPK KEDRMVYCSL TDFQKAVYQT VLETEDVALI LTSSQPCTCG
430 440 450 460 470 480
SGQKRRKCCY KTNSRGDTVR TLCLSYLTVL QKVANHVALL QAASTSKHQE TVIKRICDRV
490 500 510 520 530 540
FSRFPDFVQK SKDAAFETLS DPKYSGKMKV LQQLLNHFRK QRDKVLLFSF STKLLDVLQQ
550 560 570 580 590 600
YCMASGLDYR RLDGSTKSEE RLKIVKEFNS SQDVNICLVS TMAGGLGLNF VGANVVILFD
610 620 630 640 650 660
PTWNPANDLQ AVDRAYRIGQ CRDVKVLRLI SLGTVEEIMY LRQVYKQQLH CVVVGSENAK
670 680 690 700 710 720
RYFEAVQGSK EHRGELFGVH NLFKLRSQGS CLTRDILERE GQVEAGIMTA TTWLKGEPSA
730 740 750 760 770 780
QELETPRDPD CQEPTDVCEL YSDISDEESV GHSLGKTDKH KFSDTSRTPG FPAQLTLLQC
790 800 810 820 830 840
GFSKLFEAKY KSDQDGDGNP VPSDGSSDEQ PMCLSAEARQ AARQKTWDSV CTSEHQKSDN
850 860 870 880 890 900
IQTPDEKCVS DKSEKTLEQN VSSESDDETK DHRTAGHHCM GQGDTESEDS DVIFPTQYPT
910 920 930 940 950 960
QRIPKNHIRF KLLLGESEDS EAENPVKVNH GDDRQNSGRG NGPVPNLLCL ENMTSKSVRK
970 980 990 1000 1010 1020
RKGTDDISDE SDDIDMFPKS RIRKQRATTS LKFKRKKENK RKLDNSPVTA KEANQVCAAD
1030 1040 1050 1060 1070 1080
GDRSSQVIED FSSSDDNLSL SHLSFTKLSH RAETVKDKIS LSPKLPGPDK KNNTFISRKP
1090 1100 1110 1120 1130 1140
PSFLNEGVIS QEQICNSMDK ILDGVQEVAY IHSNQNVIGS SRAENHMSRW ATRDVFELKQ
1150 1160 1170 1180 1190 1200
FSQLPANVAV CSSKTYKTQV KANIVSPTEK DQPPSDGGIS SPLYVSHPVV QKKKDVYRTN
1210 1220 1230 1240 1250 1260
HTTFIIGETP RGIRRKQFEE MASYYKLPVK EFAEQVTRAT SEERQKMLRD FYSLQHPEVK
1270 1280 1290 1300 1310 1320
EFFVNSASEL IKSVHKKEER VRNKSKEKES LLKENPSNDS TLSCYDSTNK MSQVYNRKIC
1330 1340 1350 1360 1370 1380
EGKSVRSQNH VFHREDTFSS DAEINKSPVS FTEELHSERK DHTPKDTTTV FCPNSNSEAL
1390 1400 1410 1420 1430 1440
EAELGNSPGR QWDLTGACGS RNRPLFKLRN KRVENPGSEN TPEDGLLGDT SILNDLFKSH
1450 1460 1470 1480 1490 1500
GEGPTQLPKN VLSGPVAKAK QKPKDFWDIL NEQNDDSLSK LTDLAVIETL CTKAPSTSAS
1510 1520 1530
KRKDELEASL WKANEKFLWK TLSSDVDDES ISNTERE
Protein Neighborhood
Domains & Features
1 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| Q9JIM3-1-unknown | MDISAP... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| Q9JIM3-1-unknown | MDISAP... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt74082 | |||
| Q9JIM3-1-unknown | MDISAP... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt74084 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...LVSTMA | 582 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt69701 | |||
| ...LVSTMA | 582 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt92855 | |||
| ...NTERE | 1537 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|