TopFIND 4.0

Q9JIY2: E3 ubiquitin-protein ligase Hakai {ECO:0000305}

General Information

Protein names
- E3 ubiquitin-protein ligase Hakai {ECO:0000305}
- 2.3.2.27 {ECO:0000269|PubMed:11836526}
- Casitas B-lineage lymphoma-transforming sequence-like protein 1 {ECO:0000303|PubMed:11836526}
- c-Cbl-like protein 1 {ECO:0000303|PubMed:11836526}
- E-cadherin binding protein E7
- RING-type E3 ubiquitin transferase Hakai {ECO:0000305}
Gene names Cbll1
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q9JIY2

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MDHTDNELQG TNSSGSLGGL DVRRRIPIKL ISKQASKVKP APRTQRTVSR MPAKAPQGDE 
        70         80         90        100        110        120 
EGFDYNEEQR YDCKGGELFG NQRRFPGHLF WDFKINILGE KDDTPVHFCD KCGLPIKVYG 
       130        140        150        160        170        180 
RMIPCKHVFC YDCAILHEKK GDKMCPGCSD PVQRIEQCTR GSLFMCSIVQ GCKRTYLSQR 
       190        200        210        220        230        240 
DLQAHINHRH MRAGKPVTRA SLENVHPPIA PPPTDIPDRF IMPPDKHHMS HIPPKQHIMM 
       250        260        270        280        290        300 
PPPPLQHVPH EHYNQPHEDI RAPPAELSMA PPPPRSVSQE TFRISTRKHS NLITVPIQDD 
       310        320        330        340        350        360 
SSSGAREPPP PAPAPAHHHP EYQGQPVVSH PHHIMPPQQH YAPPPPPPPP ISHPMPHPPQ 
       370        380        390        400        410        420 
AAGTPHLVYS QAPPPPMTSA PPPITPPPGH IIAQMPPYMN HPPPGPPPPQ HGGPPVTAPP 
       430        440        450        460        470        480 
PHHYNPNSLP QFTEDQGTLS PPFTQPGGMS PGIWPAPRGP PPPPRMQGPP SQTPLPGPHH 
       490    
PDQTRYRPYY Q

Isoforms

- Isoform 2 of E3 ubiquitin-protein ligase Hakai - Isoform 3 of E3 ubiquitin-protein ligase Hakai - Isoform 4 of E3 ubiquitin-protein ligase Hakai

Sequence View

        10         20         30         40         50         60 
MDHTDNELQG TNSSGSLGGL DVRRRIPIKL ISKQASKVKP APRTQRTVSR MPAKAPQGDE 
        70         80         90        100        110        120 
EGFDYNEEQR YDCKGGELFG NQRRFPGHLF WDFKINILGE KDDTPVHFCD KCGLPIKVYG 
       130        140        150        160        170        180 
RMIPCKHVFC YDCAILHEKK GDKMCPGCSD PVQRIEQCTR GSLFMCSIVQ GCKRTYLSQR 
       190        200        210        220        230        240 
DLQAHINHRH MRAGKPVTRA SLENVHPPIA PPPTDIPDRF IMPPDKHHMS HIPPKQHIMM 
       250        260        270        280        290        300 
PPPPLQHVPH EHYNQPHEDI RAPPAELSMA PPPPRSVSQE TFRISTRKHS NLITVPIQDD 
       310        320        330        340        350        360 
SSSGAREPPP PAPAPAHHHP EYQGQPVVSH PHHIMPPQQH YAPPPPPPPP ISHPMPHPPQ 
       370        380        390        400        410        420 
AAGTPHLVYS QAPPPPMTSA PPPITPPPGH IIAQMPPYMN HPPPGPPPPQ HGGPPVTAPP 
       430        440        450        460        470        480 
PHHYNPNSLP QFTEDQGTLS PPFTQPGGMS PGIWPAPRGP PPPPRMQGPP SQTPLPGPHH 
       490    
PDQTRYRPYY Q         10         20         30         40         50         60 
MDHTDNELQG TNSSGSLGGL DVRRRIPIKL ISKQASKVKP APRTQRTVSR MPAKAPQGDE 
        70         80         90        100        110        120 
EGFDYNEEQR YDCKGGELFG NQRRFPGHLF WDFKINILGE KDDTPVHFCD KCGLPIKVYG 
       130        140        150        160        170        180 
RMIPCKHVFC YDCAILHEKK GDKMCPGCSD PVQRIEQCTR GSLFMCSIVQ GCKRTYLSQR 
       190        200        210        220        230        240 
DLQAHINHRH MRAGKPVTRA SLENVHPPIA PPPTDIPDRF IMPPDKHHMS HIPPKQHIMM 
       250        260        270        280        290        300 
PPPPLQHVPH EHYNQPHEDI RAPPAELSMA PPPPRSVSQE TFRISTRKHS NLITVPIQDD 
       310        320        330        340        350        360 
SSSGAREPPP PAPAPAHHHP EYQGQPVVSH PHHIMPPQQH YAPPPPPPPP ISHPMPHPPQ 
       370        380        390        400        410        420 
AAGTPHLVYS QAPPPPMTSA PPPITPPPGH IIAQMPPYMN HPPPGPPPPQ HGGPPVTAPP 
       430        440        450        460        470        480 
PHHYNPNSLP QFTEDQGTLS PPFTQPGGMS PGIWPAPRGP PPPPRMQGPP SQTPLPGPHH 
       490    
PDQTRYRPYY Q         10         20         30         40         50         60 
MDHTDNELQG TNSSGSLGGL DVRRRIPIKL ISKQASKVKP APRTQRTVSR MPAKAPQGDE 
        70         80         90        100        110        120 
EGFDYNEEQR YDCKGGELFG NQRRFPGHLF WDFKINILGE KDDTPVHFCD KCGLPIKVYG 
       130        140        150        160        170        180 
RMIPCKHVFC YDCAILHEKK GDKMCPGCSD PVQRIEQCTR GSLFMCSIVQ GCKRTYLSQR 
       190        200        210        220        230        240 
DLQAHINHRH MRAGKPVTRA SLENVHPPIA PPPTDIPDRF IMPPDKHHMS HIPPKQHIMM 
       250        260        270        280        290        300 
PPPPLQHVPH EHYNQPHEDI RAPPAELSMA PPPPRSVSQE TFRISTRKHS NLITVPIQDD 
       310        320        330        340        350        360 
SSSGAREPPP PAPAPAHHHP EYQGQPVVSH PHHIMPPQQH YAPPPPPPPP ISHPMPHPPQ 
       370        380        390        400        410        420 
AAGTPHLVYS QAPPPPMTSA PPPITPPPGH IIAQMPPYMN HPPPGPPPPQ HGGPPVTAPP 
       430        440        450        460        470        480 
PHHYNPNSLP QFTEDQGTLS PPFTQPGGMS PGIWPAPRGP PPPPRMQGPP SQTPLPGPHH 
       490    
PDQTRYRPYY Q



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)