TopFIND 4.0

Q9JJF9: Signal peptide peptidase-like 2A {ECO:0000250|UniProtKB:Q8TCT8}

General Information

Protein names
- Signal peptide peptidase-like 2A {ECO:0000250|UniProtKB:Q8TCT8}
- SPP-like 2A {ECO:0000250|UniProtKB:Q8TCT8}
- SPPL2a {ECO:0000250|UniProtKB:Q8TCT8}
- 3.4.23.-
- Intramembrane protease 3 {ECO:0000250|UniProtKB:Q8TCT8}
- IMP-3 {ECO:0000250|UniProtKB:Q8TCT8}
- Presenilin-like protein 2
Gene names Sppl2a
Organism Mus musculus
Protease Family
Protease ID A22.007
Chromosome location
UniProt ID Q9JJF9

2

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MGLLHSLHAP AAALLWSCLL GLAAAQEAIL HASTNGVSSL SKDYCMYYNN NWTRLPSSLE 
        70         80         90        100        110        120 
NATSLSLMNL TGTALCHLSD IPPDGIRNKA VVVHWGPCHF LEKARIAQEG GAAALLIANN 
       130        140        150        160        170        180 
SVLIPSSRNK STFQNVTVLI AVITQKDFKD MKETLGDDIT VKMYSPSWPN FDYTLVVIFV 
       190        200        210        220        230        240 
IAVFTVALGG YWSGLIELEN MKSVEDAEDR ETRKKKDDYL TFSPLTVVVF VVICCIMIVL 
       250        260        270        280        290        300 
LYFFYRWLVY VMIAIFCIAS SMSLYNCLSA LIHRMPCGQC TILCCGKNIK VSLIFLSGLC 
       310        320        330        340        350        360 
ISVAVVWAVF RNEDRWAWIL QDILGIAFCL NLIKTMKLPN FMSCVILLGL LLIYDVFFVF 
       370        380        390        400        410        420 
ITPFITKNGE SIMVELAAGP FENAEKLPVV IRVPKLMGYS VMSVCSVPVS VLGFGDIIVP 
       430        440        450        460        470        480 
GLLIAYCRRF DVQTGSSIYY ISSTIAYAVG MIITFVVLMV MKTGQPALLY LVPCTLITVS 
       490        500        510        520    
VVAWSRKEMK KFWKGSSYQV MDHLDYSTNE ENPVTTDEQI VQQ

Isoforms



Sequence View



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Directness:


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Evidence Codes:


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Protease Assignment Confidence:


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Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9JJF9-26-unknown QEAILH... 26 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9JJF9-85-unknown GIRNKA... 85 inferred from electronic annotation unknown TISdb inferred from TISdb

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)