TopFIND 4.0

Q9JJH5: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2

General Information

Protein names
- 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2
- 6PF-2-K/Fru-2,6-P2ase 2
- PFK/FBPase 2
- 6PF-2-K/Fru-2,6-P2ase heart-type isozyme
- RH2K
- 6-phosphofructo-2-kinase
- 2.7.1.105
- Fructose-2,6-bisphosphatase
- 3.1.3.46
Gene names Pfkfb2
Organism Rattus norvegicus
Protease Family
Protease ID
Chromosome location
UniProt ID Q9JJH5

3

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSENSTFSTE DSSSSSYKPH ASNLRRAGKK CSWASYMTNS PTLIVMIGLP ARGKTYVSKK 
        70         80         90        100        110        120 
LTRYLNWIGV PTKVFNLGVY RREAVKSYKS YDFFRHDNEE AMKIRKQCAL VALEDVKAYF 
       130        140        150        160        170        180 
TEESGQIAVF DATNTTRERR DMILNFAKQN AFKVFFVESV CDDPDVIAAN ILEVKVSSPD 
       190        200        210        220        230        240 
YPERNRENVM EDFLKRIECY KVTYQPLDPD NYDKDLSFIK VMNVGQRFLV NRVQDYIQSK 
       250        260        270        280        290        300 
IVYYLMNIHV HPRTIYLCRH GESEFNLLGK IGGDSGLSLR GKQFAQALKK FLEEQEIQDL 
       310        320        330        340        350        360 
KVWTSQLKRT IQTAESLGVT YEQWKILNEI DAGVCEEMTY SEIEQRYPEE FALRDQEKYL 
       370        380        390        400        410        420 
YRYPGGESYQ DLVQRLEPVI MELERQGNVL VISHQAVMRC LLAYFLDKGA DELPYLRCPL 
       430        440        450        460        470        480 
HIIFKLTPVA YGCKVETITL NVEAVDTHRD KPTHNFPKSQ TPVRMRRNSF TPLSSSNTIR 
       490        500        510        520        530        540 
RPRNYSVGSR PLKPLSPLRA LDMQEGADQP KTQVQQGSAQ ATEHLQKALE FANGHREVEN 
       550    
VLAKHRRPSM ASLTLLS

Isoforms

- Isoform 1 of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 - Isoform 2 of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 - Isoform 4 of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2

Sequence View

        10         20         30         40         50         60 
MSENSTFSTE DSSSSSYKPH ASNLRRAGKK CSWASYMTNS PTLIVMIGLP ARGKTYVSKK 
        70         80         90        100        110        120 
LTRYLNWIGV PTKVFNLGVY RREAVKSYKS YDFFRHDNEE AMKIRKQCAL VALEDVKAYF 
       130        140        150        160        170        180 
TEESGQIAVF DATNTTRERR DMILNFAKQN AFKVFFVESV CDDPDVIAAN ILEVKVSSPD 
       190        200        210        220        230        240 
YPERNRENVM EDFLKRIECY KVTYQPLDPD NYDKDLSFIK VMNVGQRFLV NRVQDYIQSK 
       250        260        270        280        290        300 
IVYYLMNIHV HPRTIYLCRH GESEFNLLGK IGGDSGLSLR GKQFAQALKK FLEEQEIQDL 
       310        320        330        340        350        360 
KVWTSQLKRT IQTAESLGVT YEQWKILNEI DAGVCEEMTY SEIEQRYPEE FALRDQEKYL 
       370        380        390        400        410        420 
YRYPGGESYQ DLVQRLEPVI MELERQGNVL VISHQAVMRC LLAYFLDKGA DELPYLRCPL 
       430        440        450        460        470        480 
HIIFKLTPVA YGCKVETITL NVEAVDTHRD KPTHNFPKSQ TPVRMRRNSF TPLSSSNTIR 
       490        500        510        520        530        540 
RPRNYSVGSR PLKPLSPLRA LDMQEGADQP KTQVQQGSAQ ATEHLQKALE FANGHREVEN 
       550    
VLAKHRRPSM ASLTLLS         10         20         30         40         50         60 
MSENSTFSTE DSSSSSYKPH ASNLRRAGKK CSWASYMTNS PTLIVMIGLP ARGKTYVSKK 
        70         80         90        100        110        120 
LTRYLNWIGV PTKVFNLGVY RREAVKSYKS YDFFRHDNEE AMKIRKQCAL VALEDVKAYF 
       130        140        150        160        170        180 
TEESGQIAVF DATNTTRERR DMILNFAKQN AFKVFFVESV CDDPDVIAAN ILEVKVSSPD 
       190        200        210        220        230        240 
YPERNRENVM EDFLKRIECY KVTYQPLDPD NYDKDLSFIK VMNVGQRFLV NRVQDYIQSK 
       250        260        270        280        290        300 
IVYYLMNIHV HPRTIYLCRH GESEFNLLGK IGGDSGLSLR GKQFAQALKK FLEEQEIQDL 
       310        320        330        340        350        360 
KVWTSQLKRT IQTAESLGVT YEQWKILNEI DAGVCEEMTY SEIEQRYPEE FALRDQEKYL 
       370        380        390        400        410        420 
YRYPGGESYQ DLVQRLEPVI MELERQGNVL VISHQAVMRC LLAYFLDKGA DELPYLRCPL 
       430        440        450        460        470        480 
HIIFKLTPVA YGCKVETITL NVEAVDTHRD KPTHNFPKSQ TPVRMRRNSF TPLSSSNTIR 
       490        500        510        520        530        540 
RPRNYSVGSR PLKPLSPLRA LDMQEGADQP KTQVQQGSAQ ATEHLQKALE FANGHREVEN 
       550    
VLAKHRRPSM ASLTLLS         10         20         30         40         50         60 
MSENSTFSTE DSSSSSYKPH ASNLRRAGKK CSWASYMTNS PTLIVMIGLP ARGKTYVSKK 
        70         80         90        100        110        120 
LTRYLNWIGV PTKVFNLGVY RREAVKSYKS YDFFRHDNEE AMKIRKQCAL VALEDVKAYF 
       130        140        150        160        170        180 
TEESGQIAVF DATNTTRERR DMILNFAKQN AFKVFFVESV CDDPDVIAAN ILEVKVSSPD 
       190        200        210        220        230        240 
YPERNRENVM EDFLKRIECY KVTYQPLDPD NYDKDLSFIK VMNVGQRFLV NRVQDYIQSK 
       250        260        270        280        290        300 
IVYYLMNIHV HPRTIYLCRH GESEFNLLGK IGGDSGLSLR GKQFAQALKK FLEEQEIQDL 
       310        320        330        340        350        360 
KVWTSQLKRT IQTAESLGVT YEQWKILNEI DAGVCEEMTY SEIEQRYPEE FALRDQEKYL 
       370        380        390        400        410        420 
YRYPGGESYQ DLVQRLEPVI MELERQGNVL VISHQAVMRC LLAYFLDKGA DELPYLRCPL 
       430        440        450        460        470        480 
HIIFKLTPVA YGCKVETITL NVEAVDTHRD KPTHNFPKSQ TPVRMRRNSF TPLSSSNTIR 
       490        500        510        520        530        540 
RPRNYSVGSR PLKPLSPLRA LDMQEGADQP KTQVQQGSAQ ATEHLQKALE FANGHREVEN 
       550    
VLAKHRRPSM ASLTLLS



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Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)