Q9JJJ7: Protein-serine O-palmitoleoyltransferase porcupine {ECO:0000305}

General Information

Protein names	- Protein-serine O-palmitoleoyltransferase porcupine {ECO:0000305} - mPORC - 2.3.1.250 {ECO:0000269\|PubMed:17141155, ECO:0000269\|PubMed:24798332}
Gene names	Porcn
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9JJJ7

1 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MATFSRQEFF QQLLQGCLLP TVQQGLDQIW LLLTICFACR LLWRLGLPSY LKHASTVAGG
        70         80         90        100        110        120
FFSLYHFFQL HMVWVVLLSL LCYLVLFLCR HSSHRGVFLS VTILIYLLMG EMHMVDTVTW
       130        140        150        160        170        180
HKMRGAQMIV AMKAVSLGFD LDRGEVGAVP SPVEFMGYLY FVGTIVFGPW ISFHSYLQAV
       190        200        210        220        230        240
QGRPLSRRWL KKVARSLALA LLCLVLSTCV GPYLFPYFIP LDGDRLLRNK KRKARGTMVR
       250        260        270        280        290        300
WLRAYESAVS FHFSNYFVGF LSEATATLAG AGFTEEKDHL EWDLTVSRPL NVELPRSMVE
       310        320        330        340        350        360
VVTSWNLPMS YWLNNYVFKN ALRLGTFSAV LVTYAASALL HGFSFHLAAV LLSLAFITYV
       370        380        390        400        410        420
EHVLRKRLAQ ILSACILSKR CLPDCSHRHR LGLGVRALNL LFGALAIFHL SYLGSLFDVD
       430        440        450        460
VDDTTEEQGY GMAYTVHKWS ELSWASHWVT FGCWIFYRLI G

Isoforms

- Isoform 2 of Protein-cysteine N-palmitoyltransferase porcupine - Isoform 3 of Protein-cysteine N-palmitoyltransferase porcupine - Isoform 4 of Protein-cysteine N-palmitoyltransferase porcupine - Isoform 5 of Protein-cysteine N-palmitoyltransferase porcupine - Isoform 2 of Protein-serine O-palmitoleoyltransferase porcupine - Isoform 3 of Protein-serine O-palmitoleoyltransferase porcupine - Isoform 4 of Protein-serine O-palmitoleoyltransferase porcupine - Isoform 5 of Protein-serine O-palmitoleoyltransferase porcupine

Sequence View

        10         20         30         40         50         60
MATFSRQEFF QQLLQGCLLP TVQQGLDQIW LLLTICFACR LLWRLGLPSY LKHASTVAGG
        70         80         90        100        110        120
FFSLYHFFQL HMVWVVLLSL LCYLVLFLCR HSSHRGVFLS VTILIYLLMG EMHMVDTVTW
       130        140        150        160        170        180
HKMRGAQMIV AMKAVSLGFD LDRGEVGAVP SPVEFMGYLY FVGTIVFGPW ISFHSYLQAV
       190        200        210        220        230        240
QGRPLSRRWL KKVARSLALA LLCLVLSTCV GPYLFPYFIP LDGDRLLRNK KRKARGTMVR
       250        260        270        280        290        300
WLRAYESAVS FHFSNYFVGF LSEATATLAG AGFTEEKDHL EWDLTVSRPL NVELPRSMVE
       310        320        330        340        350        360
VVTSWNLPMS YWLNNYVFKN ALRLGTFSAV LVTYAASALL HGFSFHLAAV LLSLAFITYV
       370        380        390        400        410        420
EHVLRKRLAQ ILSACILSKR CLPDCSHRHR LGLGVRALNL LFGALAIFHL SYLGSLFDVD
       430        440        450        460
VDDTTEEQGY GMAYTVHKWS ELSWASHWVT FGCWIFYRLI G         10         20         30         40         50         60
MATFSRQEFF QQLLQGCLLP TVQQGLDQIW LLLTICFACR LLWRLGLPSY LKHASTVAGG
        70         80         90        100        110        120
FFSLYHFFQL HMVWVVLLSL LCYLVLFLCR HSSHRGVFLS VTILIYLLMG EMHMVDTVTW
       130        140        150        160        170        180
HKMRGAQMIV AMKAVSLGFD LDRGEVGAVP SPVEFMGYLY FVGTIVFGPW ISFHSYLQAV
       190        200        210        220        230        240
QGRPLSRRWL KKVARSLALA LLCLVLSTCV GPYLFPYFIP LDGDRLLRNK KRKARGTMVR
       250        260        270        280        290        300
WLRAYESAVS FHFSNYFVGF LSEATATLAG AGFTEEKDHL EWDLTVSRPL NVELPRSMVE
       310        320        330        340        350        360
VVTSWNLPMS YWLNNYVFKN ALRLGTFSAV LVTYAASALL HGFSFHLAAV LLSLAFITYV
       370        380        390        400        410        420
EHVLRKRLAQ ILSACILSKR CLPDCSHRHR LGLGVRALNL LFGALAIFHL SYLGSLFDVD
       430        440        450        460
VDDTTEEQGY GMAYTVHKWS ELSWASHWVT FGCWIFYRLI G         10         20         30         40         50         60
MATFSRQEFF QQLLQGCLLP TVQQGLDQIW LLLTICFACR LLWRLGLPSY LKHASTVAGG
        70         80         90        100        110        120
FFSLYHFFQL HMVWVVLLSL LCYLVLFLCR HSSHRGVFLS VTILIYLLMG EMHMVDTVTW
       130        140        150        160        170        180
HKMRGAQMIV AMKAVSLGFD LDRGEVGAVP SPVEFMGYLY FVGTIVFGPW ISFHSYLQAV
       190        200        210        220        230        240
QGRPLSRRWL KKVARSLALA LLCLVLSTCV GPYLFPYFIP LDGDRLLRNK KRKARGTMVR
       250        260        270        280        290        300
WLRAYESAVS FHFSNYFVGF LSEATATLAG AGFTEEKDHL EWDLTVSRPL NVELPRSMVE
       310        320        330        340        350        360
VVTSWNLPMS YWLNNYVFKN ALRLGTFSAV LVTYAASALL HGFSFHLAAV LLSLAFITYV
       370        380        390        400        410        420
EHVLRKRLAQ ILSACILSKR CLPDCSHRHR LGLGVRALNL LFGALAIFHL SYLGSLFDVD
       430        440        450        460
VDDTTEEQGY GMAYTVHKWS ELSWASHWVT FGCWIFYRLI G         10         20         30         40         50         60
MATFSRQEFF QQLLQGCLLP TVQQGLDQIW LLLTICFACR LLWRLGLPSY LKHASTVAGG
        70         80         90        100        110        120
FFSLYHFFQL HMVWVVLLSL LCYLVLFLCR HSSHRGVFLS VTILIYLLMG EMHMVDTVTW
       130        140        150        160        170        180
HKMRGAQMIV AMKAVSLGFD LDRGEVGAVP SPVEFMGYLY FVGTIVFGPW ISFHSYLQAV
       190        200        210        220        230        240
QGRPLSRRWL KKVARSLALA LLCLVLSTCV GPYLFPYFIP LDGDRLLRNK KRKARGTMVR
       250        260        270        280        290        300
WLRAYESAVS FHFSNYFVGF LSEATATLAG AGFTEEKDHL EWDLTVSRPL NVELPRSMVE
       310        320        330        340        350        360
VVTSWNLPMS YWLNNYVFKN ALRLGTFSAV LVTYAASALL HGFSFHLAAV LLSLAFITYV
       370        380        390        400        410        420
EHVLRKRLAQ ILSACILSKR CLPDCSHRHR LGLGVRALNL LFGALAIFHL SYLGSLFDVD
       430        440        450        460
VDDTTEEQGY GMAYTVHKWS ELSWASHWVT FGCWIFYRLI G         10         20         30         40         50         60
MATFSRQEFF QQLLQGCLLP TVQQGLDQIW LLLTICFACR LLWRLGLPSY LKHASTVAGG
        70         80         90        100        110        120
FFSLYHFFQL HMVWVVLLSL LCYLVLFLCR HSSHRGVFLS VTILIYLLMG EMHMVDTVTW
       130        140        150        160        170        180
HKMRGAQMIV AMKAVSLGFD LDRGEVGAVP SPVEFMGYLY FVGTIVFGPW ISFHSYLQAV
       190        200        210        220        230        240
QGRPLSRRWL KKVARSLALA LLCLVLSTCV GPYLFPYFIP LDGDRLLRNK KRKARGTMVR
       250        260        270        280        290        300
WLRAYESAVS FHFSNYFVGF LSEATATLAG AGFTEEKDHL EWDLTVSRPL NVELPRSMVE
       310        320        330        340        350        360
VVTSWNLPMS YWLNNYVFKN ALRLGTFSAV LVTYAASALL HGFSFHLAAV LLSLAFITYV
       370        380        390        400        410        420
EHVLRKRLAQ ILSACILSKR CLPDCSHRHR LGLGVRALNL LFGALAIFHL SYLGSLFDVD
       430        440        450        460
VDDTTEEQGY GMAYTVHKWS ELSWASHWVT FGCWIFYRLI G         10         20         30         40         50         60
MATFSRQEFF QQLLQGCLLP TVQQGLDQIW LLLTICFACR LLWRLGLPSY LKHASTVAGG
        70         80         90        100        110        120
FFSLYHFFQL HMVWVVLLSL LCYLVLFLCR HSSHRGVFLS VTILIYLLMG EMHMVDTVTW
       130        140        150        160        170        180
HKMRGAQMIV AMKAVSLGFD LDRGEVGAVP SPVEFMGYLY FVGTIVFGPW ISFHSYLQAV
       190        200        210        220        230        240
QGRPLSRRWL KKVARSLALA LLCLVLSTCV GPYLFPYFIP LDGDRLLRNK KRKARGTMVR
       250        260        270        280        290        300
WLRAYESAVS FHFSNYFVGF LSEATATLAG AGFTEEKDHL EWDLTVSRPL NVELPRSMVE
       310        320        330        340        350        360
VVTSWNLPMS YWLNNYVFKN ALRLGTFSAV LVTYAASALL HGFSFHLAAV LLSLAFITYV
       370        380        390        400        410        420
EHVLRKRLAQ ILSACILSKR CLPDCSHRHR LGLGVRALNL LFGALAIFHL SYLGSLFDVD
       430        440        450        460
VDDTTEEQGY GMAYTVHKWS ELSWASHWVT FGCWIFYRLI G         10         20         30         40         50         60
MATFSRQEFF QQLLQGCLLP TVQQGLDQIW LLLTICFACR LLWRLGLPSY LKHASTVAGG
        70         80         90        100        110        120
FFSLYHFFQL HMVWVVLLSL LCYLVLFLCR HSSHRGVFLS VTILIYLLMG EMHMVDTVTW
       130        140        150        160        170        180
HKMRGAQMIV AMKAVSLGFD LDRGEVGAVP SPVEFMGYLY FVGTIVFGPW ISFHSYLQAV
       190        200        210        220        230        240
QGRPLSRRWL KKVARSLALA LLCLVLSTCV GPYLFPYFIP LDGDRLLRNK KRKARGTMVR
       250        260        270        280        290        300
WLRAYESAVS FHFSNYFVGF LSEATATLAG AGFTEEKDHL EWDLTVSRPL NVELPRSMVE
       310        320        330        340        350        360
VVTSWNLPMS YWLNNYVFKN ALRLGTFSAV LVTYAASALL HGFSFHLAAV LLSLAFITYV
       370        380        390        400        410        420
EHVLRKRLAQ ILSACILSKR CLPDCSHRHR LGLGVRALNL LFGALAIFHL SYLGSLFDVD
       430        440        450        460
VDDTTEEQGY GMAYTVHKWS ELSWASHWVT FGCWIFYRLI G         10         20         30         40         50         60
MATFSRQEFF QQLLQGCLLP TVQQGLDQIW LLLTICFACR LLWRLGLPSY LKHASTVAGG
        70         80         90        100        110        120
FFSLYHFFQL HMVWVVLLSL LCYLVLFLCR HSSHRGVFLS VTILIYLLMG EMHMVDTVTW
       130        140        150        160        170        180
HKMRGAQMIV AMKAVSLGFD LDRGEVGAVP SPVEFMGYLY FVGTIVFGPW ISFHSYLQAV
       190        200        210        220        230        240
QGRPLSRRWL KKVARSLALA LLCLVLSTCV GPYLFPYFIP LDGDRLLRNK KRKARGTMVR
       250        260        270        280        290        300
WLRAYESAVS FHFSNYFVGF LSEATATLAG AGFTEEKDHL EWDLTVSRPL NVELPRSMVE
       310        320        330        340        350        360
VVTSWNLPMS YWLNNYVFKN ALRLGTFSAV LVTYAASALL HGFSFHLAAV LLSLAFITYV
       370        380        390        400        410        420
EHVLRKRLAQ ILSACILSKR CLPDCSHRHR LGLGVRALNL LFGALAIFHL SYLGSLFDVD
       430        440        450        460
VDDTTEEQGY GMAYTVHKWS ELSWASHWVT FGCWIFYRLI G

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q9JJJ7-1-unknown	MATFSR...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9JJJ7-1-unknown	MATFSR...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt85795
Q9JJJ7-1-unknown	MATFSR...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt85796
Q9JJJ7-1-unknown	MATFSR...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt85797

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...YRLIG	461	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...YRLIG	461	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt81416
...YRLIG	461	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt81415
...YRLIG	461	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt81414
...YRLIG	461	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt81413

TopFIND

Q9JJJ7: Protein-serine O-palmitoleoyltransferase porcupine {ECO:0000305}

General Information

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates