TopFIND 4.0

Q9JJS8: Mannan-binding lectin serine protease 2

General Information

Protein names
- Mannan-binding lectin serine protease 2
- 3.4.21.104
- MBL-associated serine protease 2
- Mannose-binding protein-associated serine protease 2
- MASP-2
- Mannan-binding lectin serine protease 2 A chain
- Mannan-binding lectin serine protease 2 B chain
Gene names Masp2
Organism Rattus norvegicus
Protease Family
Protease ID S01.229
Chromosome location
UniProt ID Q9JJS8

3

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MRLLIVLGLL WSLVATLLGS KWPEPVFGRL VSLGFPEKYG NHQDRSWTLT APPGFRLRLY 
        70         80         90        100        110        120 
FTHFNLELSY RCEYDFVKLT SGTKVLATLC GQESTDTERA PGNDTFYSLG PSLKVTFHSD 
       130        140        150        160        170        180 
YSNEKPFTGF EAFYAAEDVD ECRTSLGDSV PCDHYCHNYL GGYYCSCRVG YILHQNKHTC 
       190        200        210        220        230        240 
SALCSGQVFT GRSGFLSSPE YPQPYPKLSS CAYNIRLEEG FSITLDFVES FDVEMHPEAQ 
       250        260        270        280        290        300 
CPYDSLKIQT DKREYGPFCG KTLPPRIETD SNKVTITFTT DESGNHTGWK IHYTSTAQPC 
       310        320        330        340        350        360 
PDPTAPPNGH ISPVQATYVL KDSFSVFCKT GFELLQGSVP LKSFTAVCQK DGSWDRPIPE 
       370        380        390        400        410        420 
CSIIDCGPPD DLPNGHVDYI TGPEVTTYKA VIQYSCEETF YTMSSNGKYV CEADGFWTSS 
       430        440        450        460        470        480 
KGEKSLPVCK PVCGLSTHTS GGRIIGGQPA KPGDFPWQVL LLGETTAAGA LIHDDWVLTA 
       490        500        510        520        530        540 
AHAVYGKTEA MSSLDIRMGI LKRLSLIYTQ AWPEAVFIHE GYTHGAGFDN DIALIKLKNK 
       550        560        570        580        590        600 
VTINRNIMPI CLPRKEAASL MKTDFVGTVA GWGLTQKGFL ARNLMFVDIP IVDHQKCATA 
       610        620        630        640        650        660 
YTKQPYPGAK VTVNMLCAGL DRGGKDSCRG DSGGALVFLD NETQRWFVGG IVSWGSINCG 
       670        680    
GSEQYGVYTK VTNYIPWIEN IINNF

Isoforms

- Isoform 2 of Mannan-binding lectin serine protease 2

Sequence View

        10         20         30         40         50         60 
MRLLIVLGLL WSLVATLLGS KWPEPVFGRL VSLGFPEKYG NHQDRSWTLT APPGFRLRLY 
        70         80         90        100        110        120 
FTHFNLELSY RCEYDFVKLT SGTKVLATLC GQESTDTERA PGNDTFYSLG PSLKVTFHSD 
       130        140        150        160        170        180 
YSNEKPFTGF EAFYAAEDVD ECRTSLGDSV PCDHYCHNYL GGYYCSCRVG YILHQNKHTC 
       190        200        210        220        230        240 
SALCSGQVFT GRSGFLSSPE YPQPYPKLSS CAYNIRLEEG FSITLDFVES FDVEMHPEAQ 
       250        260        270        280        290        300 
CPYDSLKIQT DKREYGPFCG KTLPPRIETD SNKVTITFTT DESGNHTGWK IHYTSTAQPC 
       310        320        330        340        350        360 
PDPTAPPNGH ISPVQATYVL KDSFSVFCKT GFELLQGSVP LKSFTAVCQK DGSWDRPIPE 
       370        380        390        400        410        420 
CSIIDCGPPD DLPNGHVDYI TGPEVTTYKA VIQYSCEETF YTMSSNGKYV CEADGFWTSS 
       430        440        450        460        470        480 
KGEKSLPVCK PVCGLSTHTS GGRIIGGQPA KPGDFPWQVL LLGETTAAGA LIHDDWVLTA 
       490        500        510        520        530        540 
AHAVYGKTEA MSSLDIRMGI LKRLSLIYTQ AWPEAVFIHE GYTHGAGFDN DIALIKLKNK 
       550        560        570        580        590        600 
VTINRNIMPI CLPRKEAASL MKTDFVGTVA GWGLTQKGFL ARNLMFVDIP IVDHQKCATA 
       610        620        630        640        650        660 
YTKQPYPGAK VTVNMLCAGL DRGGKDSCRG DSGGALVFLD NETQRWFVGG IVSWGSINCG 
       670        680    
GSEQYGVYTK VTNYIPWIEN IINNF



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Evidence Names:


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Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...TSGGRI 443 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...IINNF 685 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)