Q9JLC8: Sacsin
| Protein names | - Sacsin - DnaJ homolog subfamily C member 29 - DNAJC29 |
|---|---|
| Gene names | Sacs |
| Organism | Mus musculus |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | Q9JLC8 |
2
N-termini
1
C-termini
0
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
METKFQRWVR VTVLRGCVGC RTVAVPATAT GRDLKERIFA ETSFPVAEQR LWRGDREVPD
70 80 90 100 110 120
WIKIGDLTSK TCHLFVNLQS KGLKGGGRFG QTTPPLVDFL KDILRRYPEG GQILKELIQN
130 140 150 160 170 180
AEDAGATEVK FLYDETQYGT ETLWSKDMAQ YQGSALYVYN NAVFTPEDWH GIQEIARSRK
190 200 210 220 230 240
KDDPLKVGRF GIGFNSVYHI TDVPCIFSGD QIGMLDPHQT LFGPHESGQC WNLKDDIKEI
250 260 270 280 290 300
NELPDQFAPF IGVFGSTKET FTNGSFPGTF FRFPLRLQPS QLSSNLYTKQ KVLELFDSFR
310 320 330 340 350 360
ADADTVLLFL KSVQAVSLHV READGTEKLV FRVTASENKA LKHERPNSIK ILGTAISNYC
370 380 390 400 410 420
KKIPSNSVTC VTYHINIVLE DESTKDAQKT SWLVCNSVGG RGISSKLDSL ADELKFVPII
430 440 450 460 470 480
GLAMPLSGKD EENGAISDFS GKAFCFLPLP PGEESRTGLP VHISGFFGLT DNRRSIKWRE
490 500 510 520 530 540
LDQWRDPAAL WNEYLIVNVV PKTYATLILD SIKRLETEKS SDFPLSVDTI YKLWPEASKV
550 560 570 580 590 600
KAHWHPVLGP LFSELFQHAV IYSIGGEWVK LEQVHFSELD GSLESTRSVL NYLQSSGKQI
610 620 630 640 650 660
AKVPGNLAAA VQLSAASATS SASPVRKVTP AWVRQVLRKC AHLGSAEEKL HLLEFVLSDQ
670 680 690 700 710 720
AYSELLGLEL LPLQSGAFVP FSSSVSDQDV VYITSEEFPR SLFPGLEARL ILENLKPHLL
730 740 750 760 770 780
AALKEAAQTR GRPCTQLQLL NPERFARLIK EVMNTFWPGR ELVVQWYPFS EDKRHPSLSW
790 800 810 820 830 840
LKMVWKNLYI HFSEDLTLFD EMPLIPRTLL NEDQTCVELI RLRIPSVVIL DDETEAQLPE
850 860 870 880 890 900
FLADIVQKLG GIVLKRLDTS IQHPLVKKYI HSPLPSAILQ IMEKIPLQKL CNQIASLLPT
910 920 930 940 950 960
HKDALRKFLA SLTDTSEKEK RIIQELTIFK RINHSSDQGI SSYTKLKGCK VLDHTAKLPT
970 980 990 1000 1010 1020
DLRLSVSVID SSDEATIRLA NMLKIEKLKT TSCLKFVLKD IGNAFYTQEE VTQLMLWILE
1030 1040 1050 1060 1070 1080
NLSSLKNENS NVLDWLMPLK FIHMSQGHVV AAGDLFDPDI EVLRDLFYNE EEACFPPTIF
1090 1100 1110 1120 1130 1140
TSPDILHSLR QIGLKNESSL KEKDVVQVAR KIEALQVSSC QNQDVLMKKA KTLLLVLNKN
1150 1160 1170 1180 1190 1200
QTLLQSSEGK MALKKIKWVP ACKERPPNYP GSLVWKGDLC NLCAPPDMCD AAHAVLVGSS
1210 1220 1230 1240 1250 1260
LPLVESVHVN LEQALSIFTK PTINAVLKHF KTVVDWYTSK TFSDEDYYQF QHILLEIYGF
1270 1280 1290 1300 1310 1320
MHDHLSEGKD SFKALKFPWV WTGKNFCPLA QAVIKPTHDL DLQPYLYNVP KTMAKFHQLF
1330 1340 1350 1360 1370 1380
KACGSIEELT SDHISMVIQK VYLKSDQELS EEESKQNLHL MLNIMRWLYS NQIPASPNTP
1390 1400 1410 1420 1430 1440
VPIYHSRNPS KLVMKPIHEC CYCDIKVDDL NDLLEDSVEP IILVHEDIPM KTAEWLKVPC
1450 1460 1470 1480 1490 1500
LSTRLINPEN MGFEQSGQRE PLTVRIKNIL EEYPSVSDIF KELLQNADDA NATECSFMID
1510 1520 1530 1540 1550 1560
MRRNMDIREN LLDPGMAACH GPALWSFNNS EFSDSDFLNI TRLGESLKRG EVDKVGKFGL
1570 1580 1590 1600 1610 1620
GFNSVYHITD IPIIMSREFM IMFDPNINHI SKHIKDRSNP GIKINWSKQQ KRLRKFPNQF
1630 1640 1650 1660 1670 1680
KPFIDVFGCQ LPLAVEAPYS YNGTLFRLSF RTQQEAKVSE VSSTCYNTAD IYSLVDEFSL
1690 1700 1710 1720 1730 1740
CGHRLIIFTQ SVNSMYLKYL KIEETNPSLA QDTIIIKKKV CPSKALNAPV LSVLKEAAKL
1750 1760 1770 1780 1790 1800
MKTCSSSNKK LPTDVPKSSC ILQITVEEFH HVFRRIADLQ SPLFRGPDDD PATLFEMAKS
1810 1820 1830 1840 1850 1860
GQSKKPSDEL PQKTVDCTTW LICTCMDTGE ALKFSLNESG RRLGLVPCGA VGVLLHETQE
1870 1880 1890 1900 1910 1920
QKWTVKPHIG EVFCYLPLRI KTGLPIHING CFAVTSNRKE IWKTDTKGRW NTTFMRHVIV
1930 1940 1950 1960 1970 1980
KAYLQALSVL RDLAIGGELT DYTYYAVWPD PDLVHDDFSV ICKGFYEDIA HGKGKELTRV
1990 2000 2010 2020 2030 2040
FSDGSMWVSM KNVRFLDDSI LQRKDVGSAA FKIFLKYLKK TGSKNLCAVE LPSSVKAGFE
2050 2060 2070 2080 2090 2100
EAGCKQILLE NTFSEKQFFS EVFFPNIQEI EAELRDPLMN FVLNEKLDEF SGILRVTPCV
2110 2120 2130 2140 2150 2160
PCSLEGHPLV LPSRLIHPEG RVAKLFDTKD GRFPYGSTQD YLNPIILIKL VQLGMAKDDI
2170 2180 2190 2200 2210 2220
LWDDMLERAE SVAEINKSDH AAACLRSSIL LSLIDEKLKI KDPRAKDFAA KYQTIPFLPF
2230 2240 2250 2260 2270 2280
LTKPAGFSLE WKGNSFKPET MFAATDIYTA EYQDIVCLLQ PILNENSHSF RGCGSVSLAV
2290 2300 2310 2320 2330 2340
KEFLGLLKKP TVDLVINQLK QVAKSVDDGI TLYQENITNA CYKYLHEAVL QNEMAKATII
2350 2360 2370 2380 2390 2400
EKLKPFCFIL VENVYVESEK VSFHLNFEAA PYLYQLPNKY KNNFRELFES VGVRQSFTVE
2410 2420 2430 2440 2450 2460
DFALVLESID QERGKKQITE ENFQLCRRII SEGIWSLIRE KRQEFCEKNY GKILLPDTNL
2470 2480 2490 2500 2510 2520
LLLPAKSLCY NDCPWIKVKD STVKYCHADI PREVAVKLGA IPKRHKALER YASNICFTAL
2530 2540 2550 2560 2570 2580
GTEFGQKEKL TSRIKSILNA YPSEKEMLKE LLQNADDAKA TEICFVFDPR QHPVDRIFDD
2590 2600 2610 2620 2630 2640
KWAPLQGPAL CVYNNQPFTE DDVRGIQNLG KGTKEGNPCK TGHYGIGFNS VYHITDCPSF
2650 2660 2670 2680 2690 2700
ISGNDILGIF DPHARYAPGA TSVSPGRMFR DLDADFRTQF SDVLDLYLGN HFKLDNCTMF
2710 2720 2730 2740 2750 2760
RFPLRNAEMA QVSEISSVPS SDRMVQNLLD KLRSDGAELL MFLNHMEKIS ICEIDKATGG
2770 2780 2790 2800 2810 2820
LNVLYSVKGK ITDGDRLKRK QFHASVIDSV TKKRQLKDIP VQQITYTMDT EDSEGNLTTW
2830 2840 2850 2860 2870 2880
LICNRSGFSS MEKVSKSVIS AHKNQDITLF PRGGVAACIT HNYKKPHRAF CFLPLSLETG
2890 2900 2910 2920 2930 2940
LPFHVNGHFA LDSARRNLWR DDNGVGVRSD WNNSLMTALI APAYVELLIQ LKKRYFPGSD
2950 2960 2970 2980 2990 3000
PTLSVLQNTP IHVVKDTLKK FLSFFPVNRL DLQPDLYCLV KALYSCIHED MKRLLPVVRA
3010 3020 3030 3040 3050 3060
PNIDGSDLHS AVIITWINMS TSNKTRPFFD NLLQDELQHL KNADYNITTR KTVAENVYRL
3070 3080 3090 3100 3110 3120
KHLLLEIGFN LVYNCDETAN LYHCLVDADI PVSYVTPADV RSFLMTFSSP DTNCHIGKLP
3130 3140 3150 3160 3170 3180
CRLQQTNLKL FHSLKLLVDY CFKDAEESEF EVEGLPLLIT LDSVLQIFDG KRPKFLTTYH
3190 3200 3210 3220 3230 3240
ELIPSRKDLF MNTLYLKYSS VLLNCKVAKV FDISSFADLL SSVLPREYKT KNCAKWKDNF
3250 3260 3270 3280 3290 3300
ASESWLKNAW HFISESVSVT DDQEEPKPAF DVIVDILKDW ALLPGTKFTV STSQLVVPEG
3310 3320 3330 3340 3350 3360
DVLIPLSLMH IAVFPNAQSD KVFHALMKAG CIQLALNKIC SKDSALVPLL SCHTANIDSP
3370 3380 3390 3400 3410 3420
ASILKAVHYM VQTSTFRTEK LMENDFEALL MYFNCNLSHL MSQDDIKILK SLPCYKSISG
3430 3440 3450 3460 3470 3480
RYMSIAKFGT CYVLTKSIPS AEVEKWTQSS SSAFLEEKVH LKELYEVLGC VPVDDLEVYL
3490 3500 3510 3520 3530 3540
KHLLPKIENL SYDAKLEHLI YLKNRLASIE EPSEIKEQLF EKLESLLIIH DANNRLKQAK
3550 3560 3570 3580 3590 3600
HFYDRTVRVF EVMLPEKLFI PKEFFKKLEQ VIKPKNQAAF MTSWVEFLRN IGLKYALSQQ
3610 3620 3630 3640 3650 3660
QLLQFAKEIS VRANTENWSK ETLQSTVDIL LHHIFQERMD LLSGNFLKEL SLIPFLCPER
3670 3680 3690 3700 3710 3720
APAEYIRFHP QYQEVNGTLP LIKFNGAQVN PKFKQCDVLQ LLWTSCPILP EKATPLSIKE
3730 3740 3750 3760 3770 3780
QEGSDLAPQE QLEQVLNMLN VNLDPPLDKV INNCRNICNI TTLDEEMVKT RAKVLRSIYE
3790 3800 3810 3820 3830 3840
FLSAEKREFR FQLRGVAFVM VEDGWKLLKP EEVVINLEYE ADFKPYLYKL PLELGTFHQL
3850 3860 3870 3880 3890 3900
FKHLGTEDII STKQYVEVLS RIFKSSEGKQ LDPNEMRTVK RVVSGLFKSL QNDSVKVRSD
3910 3920 3930 3940 3950 3960
LENARDLALY LPSQDGKLVK SSILVFDDAP HYKSRIQGNI GVQMLVDLSQ CYLGKDHGFH
3970 3980 3990 4000 4010 4020
TKLIMLFPQK LRPRLLSSIL EEQLDEETPK VCQFGALCSL QGRLQLLLSS EQFITGLIRI
4030 4040 4050 4060 4070 4080
MKHENDNAFL ANEEKAIRLC KALREGLKVS CFEKLQTTLR VKGFNPIPHS RSETFAFLKR
4090 4100 4110 4120 4130 4140
FGNAVILLYI QHSDSKDINF LLALAMTLKS ATDNLISDTS YLIAMLGCND IYRISEKLDS
4150 4160 4170 4180 4190 4200
LGVKYDSSEP SKLELPMPGT PIPAEIHYTL LMDPMNVFYP GEYVGYLVDA EGGDIYGSYQ
4210 4220 4230 4240 4250 4260
PTYTYAIIVQ EVEREDADNT SFLGKIYQID IGYSEYKIVS SLDLYKFSRP DESSQNRDSA
4270 4280 4290 4300 4310 4320
PTTPTSPTEF LTPGLRSIPP LFSGKESHKS PSTKHHSPRK LKVNALPEIL KEVTSVVEQA
4330 4340 4350 4360 4370 4380
WKLPESERKK IIRRLYLKWH PDKNPENHDI ANEVFKHLQN EINRLEKQAF LDQNADRASR
4390 4400 4410 4420 4430 4440
RTFSTSASRF QSDKYSFQRF YTSWNQEATS HKSERQQQSK EKCPPSAGQT YSQRFFVPPT
4450 4460 4470 4480 4490 4500
FKSVGNPVEA RRWLRQARAN FSAARNDLHK NANEWVCFKC YLSTKLALIA ADYAVRGKSD
4510 4520 4530 4540 4550 4560
KDVKPTALAQ KIEEYSQQLE GLTNDVHTLE AYGVDSLKTR YPDLLPFPQI PNDRFTSEVA
4570 4580
MRVMECTACI IIKLENFIQQ KV
Isoforms
- Isoform 2 of Sacsin - Isoform 3 of SacsinSequence View
10 20 30 40 50 60
METKFQRWVR VTVLRGCVGC RTVAVPATAT GRDLKERIFA ETSFPVAEQR LWRGDREVPD
70 80 90 100 110 120
WIKIGDLTSK TCHLFVNLQS KGLKGGGRFG QTTPPLVDFL KDILRRYPEG GQILKELIQN
130 140 150 160 170 180
AEDAGATEVK FLYDETQYGT ETLWSKDMAQ YQGSALYVYN NAVFTPEDWH GIQEIARSRK
190 200 210 220 230 240
KDDPLKVGRF GIGFNSVYHI TDVPCIFSGD QIGMLDPHQT LFGPHESGQC WNLKDDIKEI
250 260 270 280 290 300
NELPDQFAPF IGVFGSTKET FTNGSFPGTF FRFPLRLQPS QLSSNLYTKQ KVLELFDSFR
310 320 330 340 350 360
ADADTVLLFL KSVQAVSLHV READGTEKLV FRVTASENKA LKHERPNSIK ILGTAISNYC
370 380 390 400 410 420
KKIPSNSVTC VTYHINIVLE DESTKDAQKT SWLVCNSVGG RGISSKLDSL ADELKFVPII
430 440 450 460 470 480
GLAMPLSGKD EENGAISDFS GKAFCFLPLP PGEESRTGLP VHISGFFGLT DNRRSIKWRE
490 500 510 520 530 540
LDQWRDPAAL WNEYLIVNVV PKTYATLILD SIKRLETEKS SDFPLSVDTI YKLWPEASKV
550 560 570 580 590 600
KAHWHPVLGP LFSELFQHAV IYSIGGEWVK LEQVHFSELD GSLESTRSVL NYLQSSGKQI
610 620 630 640 650 660
AKVPGNLAAA VQLSAASATS SASPVRKVTP AWVRQVLRKC AHLGSAEEKL HLLEFVLSDQ
670 680 690 700 710 720
AYSELLGLEL LPLQSGAFVP FSSSVSDQDV VYITSEEFPR SLFPGLEARL ILENLKPHLL
730 740 750 760 770 780
AALKEAAQTR GRPCTQLQLL NPERFARLIK EVMNTFWPGR ELVVQWYPFS EDKRHPSLSW
790 800 810 820 830 840
LKMVWKNLYI HFSEDLTLFD EMPLIPRTLL NEDQTCVELI RLRIPSVVIL DDETEAQLPE
850 860 870 880 890 900
FLADIVQKLG GIVLKRLDTS IQHPLVKKYI HSPLPSAILQ IMEKIPLQKL CNQIASLLPT
910 920 930 940 950 960
HKDALRKFLA SLTDTSEKEK RIIQELTIFK RINHSSDQGI SSYTKLKGCK VLDHTAKLPT
970 980 990 1000 1010 1020
DLRLSVSVID SSDEATIRLA NMLKIEKLKT TSCLKFVLKD IGNAFYTQEE VTQLMLWILE
1030 1040 1050 1060 1070 1080
NLSSLKNENS NVLDWLMPLK FIHMSQGHVV AAGDLFDPDI EVLRDLFYNE EEACFPPTIF
1090 1100 1110 1120 1130 1140
TSPDILHSLR QIGLKNESSL KEKDVVQVAR KIEALQVSSC QNQDVLMKKA KTLLLVLNKN
1150 1160 1170 1180 1190 1200
QTLLQSSEGK MALKKIKWVP ACKERPPNYP GSLVWKGDLC NLCAPPDMCD AAHAVLVGSS
1210 1220 1230 1240 1250 1260
LPLVESVHVN LEQALSIFTK PTINAVLKHF KTVVDWYTSK TFSDEDYYQF QHILLEIYGF
1270 1280 1290 1300 1310 1320
MHDHLSEGKD SFKALKFPWV WTGKNFCPLA QAVIKPTHDL DLQPYLYNVP KTMAKFHQLF
1330 1340 1350 1360 1370 1380
KACGSIEELT SDHISMVIQK VYLKSDQELS EEESKQNLHL MLNIMRWLYS NQIPASPNTP
1390 1400 1410 1420 1430 1440
VPIYHSRNPS KLVMKPIHEC CYCDIKVDDL NDLLEDSVEP IILVHEDIPM KTAEWLKVPC
1450 1460 1470 1480 1490 1500
LSTRLINPEN MGFEQSGQRE PLTVRIKNIL EEYPSVSDIF KELLQNADDA NATECSFMID
1510 1520 1530 1540 1550 1560
MRRNMDIREN LLDPGMAACH GPALWSFNNS EFSDSDFLNI TRLGESLKRG EVDKVGKFGL
1570 1580 1590 1600 1610 1620
GFNSVYHITD IPIIMSREFM IMFDPNINHI SKHIKDRSNP GIKINWSKQQ KRLRKFPNQF
1630 1640 1650 1660 1670 1680
KPFIDVFGCQ LPLAVEAPYS YNGTLFRLSF RTQQEAKVSE VSSTCYNTAD IYSLVDEFSL
1690 1700 1710 1720 1730 1740
CGHRLIIFTQ SVNSMYLKYL KIEETNPSLA QDTIIIKKKV CPSKALNAPV LSVLKEAAKL
1750 1760 1770 1780 1790 1800
MKTCSSSNKK LPTDVPKSSC ILQITVEEFH HVFRRIADLQ SPLFRGPDDD PATLFEMAKS
1810 1820 1830 1840 1850 1860
GQSKKPSDEL PQKTVDCTTW LICTCMDTGE ALKFSLNESG RRLGLVPCGA VGVLLHETQE
1870 1880 1890 1900 1910 1920
QKWTVKPHIG EVFCYLPLRI KTGLPIHING CFAVTSNRKE IWKTDTKGRW NTTFMRHVIV
1930 1940 1950 1960 1970 1980
KAYLQALSVL RDLAIGGELT DYTYYAVWPD PDLVHDDFSV ICKGFYEDIA HGKGKELTRV
1990 2000 2010 2020 2030 2040
FSDGSMWVSM KNVRFLDDSI LQRKDVGSAA FKIFLKYLKK TGSKNLCAVE LPSSVKAGFE
2050 2060 2070 2080 2090 2100
EAGCKQILLE NTFSEKQFFS EVFFPNIQEI EAELRDPLMN FVLNEKLDEF SGILRVTPCV
2110 2120 2130 2140 2150 2160
PCSLEGHPLV LPSRLIHPEG RVAKLFDTKD GRFPYGSTQD YLNPIILIKL VQLGMAKDDI
2170 2180 2190 2200 2210 2220
LWDDMLERAE SVAEINKSDH AAACLRSSIL LSLIDEKLKI KDPRAKDFAA KYQTIPFLPF
2230 2240 2250 2260 2270 2280
LTKPAGFSLE WKGNSFKPET MFAATDIYTA EYQDIVCLLQ PILNENSHSF RGCGSVSLAV
2290 2300 2310 2320 2330 2340
KEFLGLLKKP TVDLVINQLK QVAKSVDDGI TLYQENITNA CYKYLHEAVL QNEMAKATII
2350 2360 2370 2380 2390 2400
EKLKPFCFIL VENVYVESEK VSFHLNFEAA PYLYQLPNKY KNNFRELFES VGVRQSFTVE
2410 2420 2430 2440 2450 2460
DFALVLESID QERGKKQITE ENFQLCRRII SEGIWSLIRE KRQEFCEKNY GKILLPDTNL
2470 2480 2490 2500 2510 2520
LLLPAKSLCY NDCPWIKVKD STVKYCHADI PREVAVKLGA IPKRHKALER YASNICFTAL
2530 2540 2550 2560 2570 2580
GTEFGQKEKL TSRIKSILNA YPSEKEMLKE LLQNADDAKA TEICFVFDPR QHPVDRIFDD
2590 2600 2610 2620 2630 2640
KWAPLQGPAL CVYNNQPFTE DDVRGIQNLG KGTKEGNPCK TGHYGIGFNS VYHITDCPSF
2650 2660 2670 2680 2690 2700
ISGNDILGIF DPHARYAPGA TSVSPGRMFR DLDADFRTQF SDVLDLYLGN HFKLDNCTMF
2710 2720 2730 2740 2750 2760
RFPLRNAEMA QVSEISSVPS SDRMVQNLLD KLRSDGAELL MFLNHMEKIS ICEIDKATGG
2770 2780 2790 2800 2810 2820
LNVLYSVKGK ITDGDRLKRK QFHASVIDSV TKKRQLKDIP VQQITYTMDT EDSEGNLTTW
2830 2840 2850 2860 2870 2880
LICNRSGFSS MEKVSKSVIS AHKNQDITLF PRGGVAACIT HNYKKPHRAF CFLPLSLETG
2890 2900 2910 2920 2930 2940
LPFHVNGHFA LDSARRNLWR DDNGVGVRSD WNNSLMTALI APAYVELLIQ LKKRYFPGSD
2950 2960 2970 2980 2990 3000
PTLSVLQNTP IHVVKDTLKK FLSFFPVNRL DLQPDLYCLV KALYSCIHED MKRLLPVVRA
3010 3020 3030 3040 3050 3060
PNIDGSDLHS AVIITWINMS TSNKTRPFFD NLLQDELQHL KNADYNITTR KTVAENVYRL
3070 3080 3090 3100 3110 3120
KHLLLEIGFN LVYNCDETAN LYHCLVDADI PVSYVTPADV RSFLMTFSSP DTNCHIGKLP
3130 3140 3150 3160 3170 3180
CRLQQTNLKL FHSLKLLVDY CFKDAEESEF EVEGLPLLIT LDSVLQIFDG KRPKFLTTYH
3190 3200 3210 3220 3230 3240
ELIPSRKDLF MNTLYLKYSS VLLNCKVAKV FDISSFADLL SSVLPREYKT KNCAKWKDNF
3250 3260 3270 3280 3290 3300
ASESWLKNAW HFISESVSVT DDQEEPKPAF DVIVDILKDW ALLPGTKFTV STSQLVVPEG
3310 3320 3330 3340 3350 3360
DVLIPLSLMH IAVFPNAQSD KVFHALMKAG CIQLALNKIC SKDSALVPLL SCHTANIDSP
3370 3380 3390 3400 3410 3420
ASILKAVHYM VQTSTFRTEK LMENDFEALL MYFNCNLSHL MSQDDIKILK SLPCYKSISG
3430 3440 3450 3460 3470 3480
RYMSIAKFGT CYVLTKSIPS AEVEKWTQSS SSAFLEEKVH LKELYEVLGC VPVDDLEVYL
3490 3500 3510 3520 3530 3540
KHLLPKIENL SYDAKLEHLI YLKNRLASIE EPSEIKEQLF EKLESLLIIH DANNRLKQAK
3550 3560 3570 3580 3590 3600
HFYDRTVRVF EVMLPEKLFI PKEFFKKLEQ VIKPKNQAAF MTSWVEFLRN IGLKYALSQQ
3610 3620 3630 3640 3650 3660
QLLQFAKEIS VRANTENWSK ETLQSTVDIL LHHIFQERMD LLSGNFLKEL SLIPFLCPER
3670 3680 3690 3700 3710 3720
APAEYIRFHP QYQEVNGTLP LIKFNGAQVN PKFKQCDVLQ LLWTSCPILP EKATPLSIKE
3730 3740 3750 3760 3770 3780
QEGSDLAPQE QLEQVLNMLN VNLDPPLDKV INNCRNICNI TTLDEEMVKT RAKVLRSIYE
3790 3800 3810 3820 3830 3840
FLSAEKREFR FQLRGVAFVM VEDGWKLLKP EEVVINLEYE ADFKPYLYKL PLELGTFHQL
3850 3860 3870 3880 3890 3900
FKHLGTEDII STKQYVEVLS RIFKSSEGKQ LDPNEMRTVK RVVSGLFKSL QNDSVKVRSD
3910 3920 3930 3940 3950 3960
LENARDLALY LPSQDGKLVK SSILVFDDAP HYKSRIQGNI GVQMLVDLSQ CYLGKDHGFH
3970 3980 3990 4000 4010 4020
TKLIMLFPQK LRPRLLSSIL EEQLDEETPK VCQFGALCSL QGRLQLLLSS EQFITGLIRI
4030 4040 4050 4060 4070 4080
MKHENDNAFL ANEEKAIRLC KALREGLKVS CFEKLQTTLR VKGFNPIPHS RSETFAFLKR
4090 4100 4110 4120 4130 4140
FGNAVILLYI QHSDSKDINF LLALAMTLKS ATDNLISDTS YLIAMLGCND IYRISEKLDS
4150 4160 4170 4180 4190 4200
LGVKYDSSEP SKLELPMPGT PIPAEIHYTL LMDPMNVFYP GEYVGYLVDA EGGDIYGSYQ
4210 4220 4230 4240 4250 4260
PTYTYAIIVQ EVEREDADNT SFLGKIYQID IGYSEYKIVS SLDLYKFSRP DESSQNRDSA
4270 4280 4290 4300 4310 4320
PTTPTSPTEF LTPGLRSIPP LFSGKESHKS PSTKHHSPRK LKVNALPEIL KEVTSVVEQA
4330 4340 4350 4360 4370 4380
WKLPESERKK IIRRLYLKWH PDKNPENHDI ANEVFKHLQN EINRLEKQAF LDQNADRASR
4390 4400 4410 4420 4430 4440
RTFSTSASRF QSDKYSFQRF YTSWNQEATS HKSERQQQSK EKCPPSAGQT YSQRFFVPPT
4450 4460 4470 4480 4490 4500
FKSVGNPVEA RRWLRQARAN FSAARNDLHK NANEWVCFKC YLSTKLALIA ADYAVRGKSD
4510 4520 4530 4540 4550 4560
KDVKPTALAQ KIEEYSQQLE GLTNDVHTLE AYGVDSLKTR YPDLLPFPQI PNDRFTSEVA
4570 4580
MRVMECTACI IIKLENFIQQ KV
10 20 30 40 50 60
METKFQRWVR VTVLRGCVGC RTVAVPATAT GRDLKERIFA ETSFPVAEQR LWRGDREVPD
70 80 90 100 110 120
WIKIGDLTSK TCHLFVNLQS KGLKGGGRFG QTTPPLVDFL KDILRRYPEG GQILKELIQN
130 140 150 160 170 180
AEDAGATEVK FLYDETQYGT ETLWSKDMAQ YQGSALYVYN NAVFTPEDWH GIQEIARSRK
190 200 210 220 230 240
KDDPLKVGRF GIGFNSVYHI TDVPCIFSGD QIGMLDPHQT LFGPHESGQC WNLKDDIKEI
250 260 270 280 290 300
NELPDQFAPF IGVFGSTKET FTNGSFPGTF FRFPLRLQPS QLSSNLYTKQ KVLELFDSFR
310 320 330 340 350 360
ADADTVLLFL KSVQAVSLHV READGTEKLV FRVTASENKA LKHERPNSIK ILGTAISNYC
370 380 390 400 410 420
KKIPSNSVTC VTYHINIVLE DESTKDAQKT SWLVCNSVGG RGISSKLDSL ADELKFVPII
430 440 450 460 470 480
GLAMPLSGKD EENGAISDFS GKAFCFLPLP PGEESRTGLP VHISGFFGLT DNRRSIKWRE
490 500 510 520 530 540
LDQWRDPAAL WNEYLIVNVV PKTYATLILD SIKRLETEKS SDFPLSVDTI YKLWPEASKV
550 560 570 580 590 600
KAHWHPVLGP LFSELFQHAV IYSIGGEWVK LEQVHFSELD GSLESTRSVL NYLQSSGKQI
610 620 630 640 650 660
AKVPGNLAAA VQLSAASATS SASPVRKVTP AWVRQVLRKC AHLGSAEEKL HLLEFVLSDQ
670 680 690 700 710 720
AYSELLGLEL LPLQSGAFVP FSSSVSDQDV VYITSEEFPR SLFPGLEARL ILENLKPHLL
730 740 750 760 770 780
AALKEAAQTR GRPCTQLQLL NPERFARLIK EVMNTFWPGR ELVVQWYPFS EDKRHPSLSW
790 800 810 820 830 840
LKMVWKNLYI HFSEDLTLFD EMPLIPRTLL NEDQTCVELI RLRIPSVVIL DDETEAQLPE
850 860 870 880 890 900
FLADIVQKLG GIVLKRLDTS IQHPLVKKYI HSPLPSAILQ IMEKIPLQKL CNQIASLLPT
910 920 930 940 950 960
HKDALRKFLA SLTDTSEKEK RIIQELTIFK RINHSSDQGI SSYTKLKGCK VLDHTAKLPT
970 980 990 1000 1010 1020
DLRLSVSVID SSDEATIRLA NMLKIEKLKT TSCLKFVLKD IGNAFYTQEE VTQLMLWILE
1030 1040 1050 1060 1070 1080
NLSSLKNENS NVLDWLMPLK FIHMSQGHVV AAGDLFDPDI EVLRDLFYNE EEACFPPTIF
1090 1100 1110 1120 1130 1140
TSPDILHSLR QIGLKNESSL KEKDVVQVAR KIEALQVSSC QNQDVLMKKA KTLLLVLNKN
1150 1160 1170 1180 1190 1200
QTLLQSSEGK MALKKIKWVP ACKERPPNYP GSLVWKGDLC NLCAPPDMCD AAHAVLVGSS
1210 1220 1230 1240 1250 1260
LPLVESVHVN LEQALSIFTK PTINAVLKHF KTVVDWYTSK TFSDEDYYQF QHILLEIYGF
1270 1280 1290 1300 1310 1320
MHDHLSEGKD SFKALKFPWV WTGKNFCPLA QAVIKPTHDL DLQPYLYNVP KTMAKFHQLF
1330 1340 1350 1360 1370 1380
KACGSIEELT SDHISMVIQK VYLKSDQELS EEESKQNLHL MLNIMRWLYS NQIPASPNTP
1390 1400 1410 1420 1430 1440
VPIYHSRNPS KLVMKPIHEC CYCDIKVDDL NDLLEDSVEP IILVHEDIPM KTAEWLKVPC
1450 1460 1470 1480 1490 1500
LSTRLINPEN MGFEQSGQRE PLTVRIKNIL EEYPSVSDIF KELLQNADDA NATECSFMID
1510 1520 1530 1540 1550 1560
MRRNMDIREN LLDPGMAACH GPALWSFNNS EFSDSDFLNI TRLGESLKRG EVDKVGKFGL
1570 1580 1590 1600 1610 1620
GFNSVYHITD IPIIMSREFM IMFDPNINHI SKHIKDRSNP GIKINWSKQQ KRLRKFPNQF
1630 1640 1650 1660 1670 1680
KPFIDVFGCQ LPLAVEAPYS YNGTLFRLSF RTQQEAKVSE VSSTCYNTAD IYSLVDEFSL
1690 1700 1710 1720 1730 1740
CGHRLIIFTQ SVNSMYLKYL KIEETNPSLA QDTIIIKKKV CPSKALNAPV LSVLKEAAKL
1750 1760 1770 1780 1790 1800
MKTCSSSNKK LPTDVPKSSC ILQITVEEFH HVFRRIADLQ SPLFRGPDDD PATLFEMAKS
1810 1820 1830 1840 1850 1860
GQSKKPSDEL PQKTVDCTTW LICTCMDTGE ALKFSLNESG RRLGLVPCGA VGVLLHETQE
1870 1880 1890 1900 1910 1920
QKWTVKPHIG EVFCYLPLRI KTGLPIHING CFAVTSNRKE IWKTDTKGRW NTTFMRHVIV
1930 1940 1950 1960 1970 1980
KAYLQALSVL RDLAIGGELT DYTYYAVWPD PDLVHDDFSV ICKGFYEDIA HGKGKELTRV
1990 2000 2010 2020 2030 2040
FSDGSMWVSM KNVRFLDDSI LQRKDVGSAA FKIFLKYLKK TGSKNLCAVE LPSSVKAGFE
2050 2060 2070 2080 2090 2100
EAGCKQILLE NTFSEKQFFS EVFFPNIQEI EAELRDPLMN FVLNEKLDEF SGILRVTPCV
2110 2120 2130 2140 2150 2160
PCSLEGHPLV LPSRLIHPEG RVAKLFDTKD GRFPYGSTQD YLNPIILIKL VQLGMAKDDI
2170 2180 2190 2200 2210 2220
LWDDMLERAE SVAEINKSDH AAACLRSSIL LSLIDEKLKI KDPRAKDFAA KYQTIPFLPF
2230 2240 2250 2260 2270 2280
LTKPAGFSLE WKGNSFKPET MFAATDIYTA EYQDIVCLLQ PILNENSHSF RGCGSVSLAV
2290 2300 2310 2320 2330 2340
KEFLGLLKKP TVDLVINQLK QVAKSVDDGI TLYQENITNA CYKYLHEAVL QNEMAKATII
2350 2360 2370 2380 2390 2400
EKLKPFCFIL VENVYVESEK VSFHLNFEAA PYLYQLPNKY KNNFRELFES VGVRQSFTVE
2410 2420 2430 2440 2450 2460
DFALVLESID QERGKKQITE ENFQLCRRII SEGIWSLIRE KRQEFCEKNY GKILLPDTNL
2470 2480 2490 2500 2510 2520
LLLPAKSLCY NDCPWIKVKD STVKYCHADI PREVAVKLGA IPKRHKALER YASNICFTAL
2530 2540 2550 2560 2570 2580
GTEFGQKEKL TSRIKSILNA YPSEKEMLKE LLQNADDAKA TEICFVFDPR QHPVDRIFDD
2590 2600 2610 2620 2630 2640
KWAPLQGPAL CVYNNQPFTE DDVRGIQNLG KGTKEGNPCK TGHYGIGFNS VYHITDCPSF
2650 2660 2670 2680 2690 2700
ISGNDILGIF DPHARYAPGA TSVSPGRMFR DLDADFRTQF SDVLDLYLGN HFKLDNCTMF
2710 2720 2730 2740 2750 2760
RFPLRNAEMA QVSEISSVPS SDRMVQNLLD KLRSDGAELL MFLNHMEKIS ICEIDKATGG
2770 2780 2790 2800 2810 2820
LNVLYSVKGK ITDGDRLKRK QFHASVIDSV TKKRQLKDIP VQQITYTMDT EDSEGNLTTW
2830 2840 2850 2860 2870 2880
LICNRSGFSS MEKVSKSVIS AHKNQDITLF PRGGVAACIT HNYKKPHRAF CFLPLSLETG
2890 2900 2910 2920 2930 2940
LPFHVNGHFA LDSARRNLWR DDNGVGVRSD WNNSLMTALI APAYVELLIQ LKKRYFPGSD
2950 2960 2970 2980 2990 3000
PTLSVLQNTP IHVVKDTLKK FLSFFPVNRL DLQPDLYCLV KALYSCIHED MKRLLPVVRA
3010 3020 3030 3040 3050 3060
PNIDGSDLHS AVIITWINMS TSNKTRPFFD NLLQDELQHL KNADYNITTR KTVAENVYRL
3070 3080 3090 3100 3110 3120
KHLLLEIGFN LVYNCDETAN LYHCLVDADI PVSYVTPADV RSFLMTFSSP DTNCHIGKLP
3130 3140 3150 3160 3170 3180
CRLQQTNLKL FHSLKLLVDY CFKDAEESEF EVEGLPLLIT LDSVLQIFDG KRPKFLTTYH
3190 3200 3210 3220 3230 3240
ELIPSRKDLF MNTLYLKYSS VLLNCKVAKV FDISSFADLL SSVLPREYKT KNCAKWKDNF
3250 3260 3270 3280 3290 3300
ASESWLKNAW HFISESVSVT DDQEEPKPAF DVIVDILKDW ALLPGTKFTV STSQLVVPEG
3310 3320 3330 3340 3350 3360
DVLIPLSLMH IAVFPNAQSD KVFHALMKAG CIQLALNKIC SKDSALVPLL SCHTANIDSP
3370 3380 3390 3400 3410 3420
ASILKAVHYM VQTSTFRTEK LMENDFEALL MYFNCNLSHL MSQDDIKILK SLPCYKSISG
3430 3440 3450 3460 3470 3480
RYMSIAKFGT CYVLTKSIPS AEVEKWTQSS SSAFLEEKVH LKELYEVLGC VPVDDLEVYL
3490 3500 3510 3520 3530 3540
KHLLPKIENL SYDAKLEHLI YLKNRLASIE EPSEIKEQLF EKLESLLIIH DANNRLKQAK
3550 3560 3570 3580 3590 3600
HFYDRTVRVF EVMLPEKLFI PKEFFKKLEQ VIKPKNQAAF MTSWVEFLRN IGLKYALSQQ
3610 3620 3630 3640 3650 3660
QLLQFAKEIS VRANTENWSK ETLQSTVDIL LHHIFQERMD LLSGNFLKEL SLIPFLCPER
3670 3680 3690 3700 3710 3720
APAEYIRFHP QYQEVNGTLP LIKFNGAQVN PKFKQCDVLQ LLWTSCPILP EKATPLSIKE
3730 3740 3750 3760 3770 3780
QEGSDLAPQE QLEQVLNMLN VNLDPPLDKV INNCRNICNI TTLDEEMVKT RAKVLRSIYE
3790 3800 3810 3820 3830 3840
FLSAEKREFR FQLRGVAFVM VEDGWKLLKP EEVVINLEYE ADFKPYLYKL PLELGTFHQL
3850 3860 3870 3880 3890 3900
FKHLGTEDII STKQYVEVLS RIFKSSEGKQ LDPNEMRTVK RVVSGLFKSL QNDSVKVRSD
3910 3920 3930 3940 3950 3960
LENARDLALY LPSQDGKLVK SSILVFDDAP HYKSRIQGNI GVQMLVDLSQ CYLGKDHGFH
3970 3980 3990 4000 4010 4020
TKLIMLFPQK LRPRLLSSIL EEQLDEETPK VCQFGALCSL QGRLQLLLSS EQFITGLIRI
4030 4040 4050 4060 4070 4080
MKHENDNAFL ANEEKAIRLC KALREGLKVS CFEKLQTTLR VKGFNPIPHS RSETFAFLKR
4090 4100 4110 4120 4130 4140
FGNAVILLYI QHSDSKDINF LLALAMTLKS ATDNLISDTS YLIAMLGCND IYRISEKLDS
4150 4160 4170 4180 4190 4200
LGVKYDSSEP SKLELPMPGT PIPAEIHYTL LMDPMNVFYP GEYVGYLVDA EGGDIYGSYQ
4210 4220 4230 4240 4250 4260
PTYTYAIIVQ EVEREDADNT SFLGKIYQID IGYSEYKIVS SLDLYKFSRP DESSQNRDSA
4270 4280 4290 4300 4310 4320
PTTPTSPTEF LTPGLRSIPP LFSGKESHKS PSTKHHSPRK LKVNALPEIL KEVTSVVEQA
4330 4340 4350 4360 4370 4380
WKLPESERKK IIRRLYLKWH PDKNPENHDI ANEVFKHLQN EINRLEKQAF LDQNADRASR
4390 4400 4410 4420 4430 4440
RTFSTSASRF QSDKYSFQRF YTSWNQEATS HKSERQQQSK EKCPPSAGQT YSQRFFVPPT
4450 4460 4470 4480 4490 4500
FKSVGNPVEA RRWLRQARAN FSAARNDLHK NANEWVCFKC YLSTKLALIA ADYAVRGKSD
4510 4520 4530 4540 4550 4560
KDVKPTALAQ KIEEYSQQLE GLTNDVHTLE AYGVDSLKTR YPDLLPFPQI PNDRFTSEVA
4570 4580
MRVMECTACI IIKLENFIQQ KV
Protein Neighborhood
Domains & Features
2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| Q9JLC8-1-unknown | METKFQ... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| Q9JLC8-753-unknown | MNTFWP... | 753 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt88831 | |||
| Q9JLC8-753-unknown | MNTFWP... | 753 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt110000 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...IQQKV | 4582 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| ...IQQKV | 4582 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt84449 | |||
| ...IQQKV | 4582 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt84450 |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|