TopFIND 4.0

Q9JLT4: Thioredoxin reductase 2, mitochondrial

General Information

Protein names
- Thioredoxin reductase 2, mitochondrial
- 1.8.1.9
- Thioredoxin reductase TR3
Gene names Txnrd2
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q9JLT4

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MVAAMVAALR GPSRRFRPRT RALTRGTRGA ASAAGGQQSF DLLVIGGGSG GLACAKEAAQ 
        70         80         90        100        110        120 
LGKKVAVADY VEPSPRGTKW GLGGTCVNVG CIPKKLMHQA ALLGGMIRDA HHYGWEVAQP 
       130        140        150        160        170        180 
VQHNWKTMAE AVQNHVKSLN WGHRVQLQDR KVKYFNIKAS FVDEHTVRGV DKGGKATLLS 
       190        200        210        220        230        240 
AEHIVIATGG RPRYPTQVKG ALEYGITSDD IFWLKESPGK TLVVGASYVA LECAGFLTGI 
       250        260        270        280        290        300 
GLDTTVMMRS IPLRGFDQQM SSLVTEHMES HGTQFLKGCV PSHIKKLPTN QLQVTWEDHA 
       310        320        330        340        350        360 
SGKEDTGTFD TVLWAIGRVP ETRTLNLEKA GISTNPKNQK IIVDAQEATS VPHIYAIGDV 
       370        380        390        400        410        420 
AEGRPELTPT AIKAGKLLAQ RLFGKSSTLM DYSNVPTTVF TPLEYGCVGL SEEEAVALHG 
       430        440        450        460        470        480 
QEHVEVYHAY YKPLEFTVAD RDASQCYIKM VCMREPPQLV LGLHFLGPNA GEVTQGFALG 
       490        500        510        520    
IKCGASYAQV MQTVGIHPTC SEEVVKLHIS KRSGLEPTVT GCUG

Isoforms

- Isoform 2 of Thioredoxin reductase 2, mitochondrial - Isoform 3 of Thioredoxin reductase 2, mitochondrial - Isoform 4 of Thioredoxin reductase 2, mitochondrial

Sequence View

        10         20         30         40         50         60 
MVAAMVAALR GPSRRFRPRT RALTRGTRGA ASAAGGQQSF DLLVIGGGSG GLACAKEAAQ 
        70         80         90        100        110        120 
LGKKVAVADY VEPSPRGTKW GLGGTCVNVG CIPKKLMHQA ALLGGMIRDA HHYGWEVAQP 
       130        140        150        160        170        180 
VQHNWKTMAE AVQNHVKSLN WGHRVQLQDR KVKYFNIKAS FVDEHTVRGV DKGGKATLLS 
       190        200        210        220        230        240 
AEHIVIATGG RPRYPTQVKG ALEYGITSDD IFWLKESPGK TLVVGASYVA LECAGFLTGI 
       250        260        270        280        290        300 
GLDTTVMMRS IPLRGFDQQM SSLVTEHMES HGTQFLKGCV PSHIKKLPTN QLQVTWEDHA 
       310        320        330        340        350        360 
SGKEDTGTFD TVLWAIGRVP ETRTLNLEKA GISTNPKNQK IIVDAQEATS VPHIYAIGDV 
       370        380        390        400        410        420 
AEGRPELTPT AIKAGKLLAQ RLFGKSSTLM DYSNVPTTVF TPLEYGCVGL SEEEAVALHG 
       430        440        450        460        470        480 
QEHVEVYHAY YKPLEFTVAD RDASQCYIKM VCMREPPQLV LGLHFLGPNA GEVTQGFALG 
       490        500        510        520    
IKCGASYAQV MQTVGIHPTC SEEVVKLHIS KRSGLEPTVT GCUG         10         20         30         40         50         60 
MVAAMVAALR GPSRRFRPRT RALTRGTRGA ASAAGGQQSF DLLVIGGGSG GLACAKEAAQ 
        70         80         90        100        110        120 
LGKKVAVADY VEPSPRGTKW GLGGTCVNVG CIPKKLMHQA ALLGGMIRDA HHYGWEVAQP 
       130        140        150        160        170        180 
VQHNWKTMAE AVQNHVKSLN WGHRVQLQDR KVKYFNIKAS FVDEHTVRGV DKGGKATLLS 
       190        200        210        220        230        240 
AEHIVIATGG RPRYPTQVKG ALEYGITSDD IFWLKESPGK TLVVGASYVA LECAGFLTGI 
       250        260        270        280        290        300 
GLDTTVMMRS IPLRGFDQQM SSLVTEHMES HGTQFLKGCV PSHIKKLPTN QLQVTWEDHA 
       310        320        330        340        350        360 
SGKEDTGTFD TVLWAIGRVP ETRTLNLEKA GISTNPKNQK IIVDAQEATS VPHIYAIGDV 
       370        380        390        400        410        420 
AEGRPELTPT AIKAGKLLAQ RLFGKSSTLM DYSNVPTTVF TPLEYGCVGL SEEEAVALHG 
       430        440        450        460        470        480 
QEHVEVYHAY YKPLEFTVAD RDASQCYIKM VCMREPPQLV LGLHFLGPNA GEVTQGFALG 
       490        500        510        520    
IKCGASYAQV MQTVGIHPTC SEEVVKLHIS KRSGLEPTVT GCUG         10         20         30         40         50         60 
MVAAMVAALR GPSRRFRPRT RALTRGTRGA ASAAGGQQSF DLLVIGGGSG GLACAKEAAQ 
        70         80         90        100        110        120 
LGKKVAVADY VEPSPRGTKW GLGGTCVNVG CIPKKLMHQA ALLGGMIRDA HHYGWEVAQP 
       130        140        150        160        170        180 
VQHNWKTMAE AVQNHVKSLN WGHRVQLQDR KVKYFNIKAS FVDEHTVRGV DKGGKATLLS 
       190        200        210        220        230        240 
AEHIVIATGG RPRYPTQVKG ALEYGITSDD IFWLKESPGK TLVVGASYVA LECAGFLTGI 
       250        260        270        280        290        300 
GLDTTVMMRS IPLRGFDQQM SSLVTEHMES HGTQFLKGCV PSHIKKLPTN QLQVTWEDHA 
       310        320        330        340        350        360 
SGKEDTGTFD TVLWAIGRVP ETRTLNLEKA GISTNPKNQK IIVDAQEATS VPHIYAIGDV 
       370        380        390        400        410        420 
AEGRPELTPT AIKAGKLLAQ RLFGKSSTLM DYSNVPTTVF TPLEYGCVGL SEEEAVALHG 
       430        440        450        460        470        480 
QEHVEVYHAY YKPLEFTVAD RDASQCYIKM VCMREPPQLV LGLHFLGPNA GEVTQGFALG 
       490        500        510        520    
IKCGASYAQV MQTVGIHPTC SEEVVKLHIS KRSGLEPTVT GCUG



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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)