TopFIND 4.0

Q9JLZ6: Hypermethylated in cancer 2 protein

General Information

Protein names
- Hypermethylated in cancer 2 protein
- Hic-2
Gene names Hic2
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q9JLZ6

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MVSGPLALRW CPWAGHRDMG PDMELPSHSK QLLLQLNQQR AKGFLCDVII MVENSIFRAH 
        70         80         90        100        110        120 
KNVLAASSIY FKSLVLHDNL INLDTDMVSS TVFQQILDFI YTGKLLPSDQ PSEPNFSTLL 
       130        140        150        160        170        180 
TAASYLQLPE LAALCRRKLK RAGKPFGPGR VGTAGIGRPT RSQRLSTASV IQARFPGLVD 
       190        200        210        220        230        240 
VRKGHPAPQE LPQAKGSDDE LFLGTSTQES THGLGLGGPA GGEMGLGGCS TSTNGSSGGC 
       250        260        270        280        290        300 
EQELGLDLSK KSPPLPPTTP GPHLTPEDPA QLSDSQRESP APTSTSALPV GNSASFVELG 
       310        320        330        340        350        360 
ATPEEPMDVE GAEENHLSLL EGQGGQPRKS LRHSARKKDW NKKEPVAGSP FDRRETGSKG 
       370        380        390        400        410        420 
SCPGEEGEGT GDRVPNGVLA SSAGGGGPSA SYGEQSFPCK EEEENGKDGS EDSGQSGSEG 
       430        440        450        460        470        480 
GSGHTGAHYV YRQEGYETVS YGDNVYVCIP CAKGFPSSEQ LNAHVETHTE EELFIKEEGA 
       490        500        510        520        530        540 
YETGSGGAEE EAEDLSTPSA AYTADSRPFK CSVCEKTYKD PATLRQHEKT HWLTRPFPCN 
       550        560        570        580        590        600 
ICGKMFTQRG TMTRHMRSHL GLKPFACDEC GMRFTRQYRL TEHMRVHSGE KPYECQLCGG 
       610    
KFTQQRNLIS HLRMHTSPS

Isoforms

- Isoform 2 of Hypermethylated in cancer 2 protein

Sequence View

        10         20         30         40         50         60 
MVSGPLALRW CPWAGHRDMG PDMELPSHSK QLLLQLNQQR AKGFLCDVII MVENSIFRAH 
        70         80         90        100        110        120 
KNVLAASSIY FKSLVLHDNL INLDTDMVSS TVFQQILDFI YTGKLLPSDQ PSEPNFSTLL 
       130        140        150        160        170        180 
TAASYLQLPE LAALCRRKLK RAGKPFGPGR VGTAGIGRPT RSQRLSTASV IQARFPGLVD 
       190        200        210        220        230        240 
VRKGHPAPQE LPQAKGSDDE LFLGTSTQES THGLGLGGPA GGEMGLGGCS TSTNGSSGGC 
       250        260        270        280        290        300 
EQELGLDLSK KSPPLPPTTP GPHLTPEDPA QLSDSQRESP APTSTSALPV GNSASFVELG 
       310        320        330        340        350        360 
ATPEEPMDVE GAEENHLSLL EGQGGQPRKS LRHSARKKDW NKKEPVAGSP FDRRETGSKG 
       370        380        390        400        410        420 
SCPGEEGEGT GDRVPNGVLA SSAGGGGPSA SYGEQSFPCK EEEENGKDGS EDSGQSGSEG 
       430        440        450        460        470        480 
GSGHTGAHYV YRQEGYETVS YGDNVYVCIP CAKGFPSSEQ LNAHVETHTE EELFIKEEGA 
       490        500        510        520        530        540 
YETGSGGAEE EAEDLSTPSA AYTADSRPFK CSVCEKTYKD PATLRQHEKT HWLTRPFPCN 
       550        560        570        580        590        600 
ICGKMFTQRG TMTRHMRSHL GLKPFACDEC GMRFTRQYRL TEHMRVHSGE KPYECQLCGG 
       610    
KFTQQRNLIS HLRMHTSPS



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9JLZ6-1-unknown MVSGPL... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9JLZ6-1-unknown MVSGPL... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt76986

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...HTSPS 619 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)