Q9NNW5: WD repeat-containing protein 6

General Information

Protein names	- WD repeat-containing protein 6
Gene names	WDR6
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9NNW5

2 N-termini

6 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MDALEDYVWP RATSELILLP VTGLECVGDR LLAGEGPDVL VYSLDFGGHL RMIKRVQNLL
        70         80         90        100        110        120
GHYLIHGFRV RPEPNGDLDL EAMVAVFGSK GLRVVKISWG QGHFWELWRS GLWNMSDWIW
       130        140        150        160        170        180
DARWLEGNIA LALGHNSVVL YDPVVGCILQ EVPCTDRCTL SSACLIGDAW KELTIVAGAV
       190        200        210        220        230        240
SNQLLVWYPA TALADNKPVA PDRRISGHVG IIFSMSYLES KGLLATASED RSVRIWKVGD
       250        260        270        280        290        300
LRVPGGRVQN IGHCFGHSAR VWQVKLLENY LISAGEDCVC LVWSHEGEIL QAFRGHQGRG
       310        320        330        340        350        360
IRAIAAHERQ AWVITGGDDS GIRLWHLVGR GYRGLGVSAL CFKSRSRPGT LKAVTLAGSW
       370        380        390        400        410        420
RLLAVTDTGA LYLYDVEVKC WEQLLEDKHF QSYCLLEAAP GPEGFGLCAM ANGEGRVKVV
       430        440        450        460        470        480
PINTPTAAVD QTLFPGKVHS LSWALRGYEE LLLLASGPGG VVACLEISAA PSGKAIFVKE
       490        500        510        520        530        540
RCRYLLPPSK QRWHTCSAFL PPGDFLVCGD RRGSVLLFPS RPGLLKDPGV GGKARAGAGA
       550        560        570        580        590        600
PVVGSGSSGG GNAFTGLGPV STLPSLHGKQ GVTSVTCHGG YVYTTGRDGA YYQLFVRDGQ
       610        620        630        640        650        660
LQPVLRQKSC RGMNWLAGLR IVPDGSMVIL GFHANEFVVW NPRSHEKLHI VNCGGGHRSW
       670        680        690        700        710        720
AFSDTEAAMA FAYLKDGDVM LYRALGGCTR PHVILREGLH GREITCVKRV GTITLGPEYG
       730        740        750        760        770        780
VPSFMQPDDL EPGSEGPDLT DIVITCSEDT TVCVLALPTT TGSAHALTAV CNHISSVRAV
       790        800        810        820        830        840
AVWGIGTPGG PQDPQPGLTA HVVSAGGRAE MHCFSIMVTP DPSTPSRLAC HVMHLSSHRL
       850        860        870        880        890        900
DEYWDRQRNR HRMVKVDPET RYMSLAVCEL DQPGLGPLVA AACSDGAVRL FLLQDSGRIL
       910        920        930        940        950        960
QLLAETFHHK RCVLKVHSFT HEAPNQRRRL LLCSAATDGS LAFWDLTTML DHDSTVLEPP
       970        980        990       1000       1010       1020
VDPGLPYRLG TPSLTLQAHS CGINSLHTLP TREGHHLVAS GSEDGSLHVF VLAVEMLQLE
      1030       1040       1050       1060       1070       1080
EAVGEAGLVP QLRVLEEYSV PCAHAAHVTG LKILSPSIMV SASIDQRLTF WRLGHGEPTF
      1090       1100       1110       1120
MNSTVFHVPD VADMDCWPVS PEFGHRCALG GQGLEVYNWY D

Isoforms

Sequence View

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(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 6 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9NNW5-1-Acetylation	MDALED...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9NNW5-1-Acetylation	MDALED...	1	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human
Q9NNW5-1-Acetylation	MDALED...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q9NNW5-52-unknown	MIKRVQ...	52		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000413432
Q9NNW5-52-unknown	MIKRVQ...	52		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000477087
Q9NNW5-52-unknown	MIKRVQ...	52		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000477463

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...IKRVQN	57	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000477418
...AMVAVF	86	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000477463
...DARWLE	125	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000390740
...ELTIVA	176	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000477087
...IWKVGD	239	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000387692
...YNWYD	1121	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)