TopFIND 4.0

Q9NPH2: Inositol-3-phosphate synthase 1

General Information

Protein names
- Inositol-3-phosphate synthase 1
- IPS 1
- 5.5.1.4
- Myo-inositol 1-phosphate synthase
- MI-1-P synthase
- MIP synthase
- hIPS
- Myo-inositol 1-phosphate synthase A1
- hINO1
Gene names ISYNA1
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q9NPH2

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MEAAAQFFVE SPDVVYGPEA IEAQYEYRTT RVSREGGVLK VHPTSTRFTF RTARQVPRLG 
        70         80         90        100        110        120 
VMLVGWGGNN GSTLTAAVLA NRLRLSWPTR SGRKEANYYG SLTQAGTVSL GLDAEGQEVF 
       130        140        150        160        170        180 
VPFSAVLPMV APNDLVFDGW DISSLNLAEA MRRAKVLDWG LQEQLWPHME ALRPRPSVYI 
       190        200        210        220        230        240 
PEFIAANQSA RADNLIPGSR AQQLEQIRRD IRDFRSSAGL DKVIVLWTAN TERFCEVIPG 
       250        260        270        280        290        300 
LNDTAENLLR TIELGLEVSP STLFAVASIL EGCAFLNGSP QNTLVPGALE LAWQHRVFVG 
       310        320        330        340        350        360 
GDDFKSGQTK VKSVLVDFLI GSGLKTMSIV SYNHLGNNDG ENLSAPLQFR SKEVSKSNVV 
       370        380        390        400        410        420 
DDMVQSNPVL YTPGEEPDHC VVIKYVPYVG DSKRALDEYT SELMLGGTNT LVLHNTCEDS 
       430        440        450        460        470        480 
LLAAPIMLDL ALLTELCQRV SFCTDMDPEP QTFHPVLSLL SFLFKAPLVP PGSPVVNALF 
       490        500        510        520        530        540 
RQRSCIENIL RACVGLPPQN HMLLEHKMER PGPSLKRVGP VAATYPMLNK KGPVPAATNG 
       550    
CTGDANGHLQ EEPPMPTT

Isoforms

- Isoform 2 of Inositol-3-phosphate synthase 1 - Isoform 3 of Inositol-3-phosphate synthase 1

Sequence View

        10         20         30         40         50         60 
MEAAAQFFVE SPDVVYGPEA IEAQYEYRTT RVSREGGVLK VHPTSTRFTF RTARQVPRLG 
        70         80         90        100        110        120 
VMLVGWGGNN GSTLTAAVLA NRLRLSWPTR SGRKEANYYG SLTQAGTVSL GLDAEGQEVF 
       130        140        150        160        170        180 
VPFSAVLPMV APNDLVFDGW DISSLNLAEA MRRAKVLDWG LQEQLWPHME ALRPRPSVYI 
       190        200        210        220        230        240 
PEFIAANQSA RADNLIPGSR AQQLEQIRRD IRDFRSSAGL DKVIVLWTAN TERFCEVIPG 
       250        260        270        280        290        300 
LNDTAENLLR TIELGLEVSP STLFAVASIL EGCAFLNGSP QNTLVPGALE LAWQHRVFVG 
       310        320        330        340        350        360 
GDDFKSGQTK VKSVLVDFLI GSGLKTMSIV SYNHLGNNDG ENLSAPLQFR SKEVSKSNVV 
       370        380        390        400        410        420 
DDMVQSNPVL YTPGEEPDHC VVIKYVPYVG DSKRALDEYT SELMLGGTNT LVLHNTCEDS 
       430        440        450        460        470        480 
LLAAPIMLDL ALLTELCQRV SFCTDMDPEP QTFHPVLSLL SFLFKAPLVP PGSPVVNALF 
       490        500        510        520        530        540 
RQRSCIENIL RACVGLPPQN HMLLEHKMER PGPSLKRVGP VAATYPMLNK KGPVPAATNG 
       550    
CTGDANGHLQ EEPPMPTT         10         20         30         40         50         60 
MEAAAQFFVE SPDVVYGPEA IEAQYEYRTT RVSREGGVLK VHPTSTRFTF RTARQVPRLG 
        70         80         90        100        110        120 
VMLVGWGGNN GSTLTAAVLA NRLRLSWPTR SGRKEANYYG SLTQAGTVSL GLDAEGQEVF 
       130        140        150        160        170        180 
VPFSAVLPMV APNDLVFDGW DISSLNLAEA MRRAKVLDWG LQEQLWPHME ALRPRPSVYI 
       190        200        210        220        230        240 
PEFIAANQSA RADNLIPGSR AQQLEQIRRD IRDFRSSAGL DKVIVLWTAN TERFCEVIPG 
       250        260        270        280        290        300 
LNDTAENLLR TIELGLEVSP STLFAVASIL EGCAFLNGSP QNTLVPGALE LAWQHRVFVG 
       310        320        330        340        350        360 
GDDFKSGQTK VKSVLVDFLI GSGLKTMSIV SYNHLGNNDG ENLSAPLQFR SKEVSKSNVV 
       370        380        390        400        410        420 
DDMVQSNPVL YTPGEEPDHC VVIKYVPYVG DSKRALDEYT SELMLGGTNT LVLHNTCEDS 
       430        440        450        460        470        480 
LLAAPIMLDL ALLTELCQRV SFCTDMDPEP QTFHPVLSLL SFLFKAPLVP PGSPVVNALF 
       490        500        510        520        530        540 
RQRSCIENIL RACVGLPPQN HMLLEHKMER PGPSLKRVGP VAATYPMLNK KGPVPAATNG 
       550    
CTGDANGHLQ EEPPMPTT



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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9NPH2-1-unknown MEAAAQ... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9NPH2-1-unknown MEAAAQ... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt77919
    Q9NPH2-129-unknown MVAPND... 129 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt77918
    Q9NPH2-129-unknown MVAPND... 129 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt101230

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)