TopFIND 4.0

Q9NQ76: Matrix extracellular phosphoglycoprotein {ECO:0000303|PubMed:10945470}

General Information

Protein names
- Matrix extracellular phosphoglycoprotein {ECO:0000303|PubMed:10945470}
- Osteoblast/osteocyte factor 45 {ECO:0000250|UniProtKB:Q8K4L6}
- OF45 {ECO:0000250|UniProtKB:Q8K4L6}
- Osteoregulin {ECO:0000303|PubMed:12489176}
Gene names MEPE
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q9NQ76

3

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MRVFCVGLLL FSVTWAAPTF QPQTEKTKQS CVEEQRQEEK NKDNIGFHHL GKRINQELSS 
        70         80         90        100        110        120 
KENIVQERKK DLSLSEASEN KGSSKSQNYF TNRQRLNKEY SISNKENTHN GLRMSIYPKS 
       130        140        150        160        170        180 
TGNKGFEDGD DAISKLHDQE EYGAALIRNN MQHIMGPVTA IKLLGEENKE NTPRNVLNII 
       190        200        210        220        230        240 
PASMNYAKAH SKDKKKPQRD SQAQKSPVKS KSTHRIQHNI DYLKHLSKVK KIPSDFEGSG 
       250        260        270        280        290        300 
YTDLQERGDN DISPFSGDGQ PFKDIPGKGE ATGPDLEGKD IQTGFAGPSE AESTHLDTKK 
       310        320        330        340        350        360 
PGYNEIPERE ENGGNTIGTR DETAKEADAV DVSLVEGSND IMGSTNFKEL PGREGNRVDA 
       370        380        390        400        410        420 
GSQNAHQGKV EFHYPPAPSK EKRKEGSSDA AESTNYNEIP KNGKGSTRKG VDHSNRNQAT 
       430        440        450        460        470        480 
LNEKQRFPSK GKSQGLPIPS RGLDNEIKNE MDSFNGPSHE NIITHGRKYH YVPHRQNNST 
       490        500        510        520    
RNKGMPQGKG SWGRQPHSNR RFSSRRRDDS SESSDSGSSS ESDGD

Isoforms

- Isoform 2 of Matrix extracellular phosphoglycoprotein - Isoform 3 of Matrix extracellular phosphoglycoprotein

Sequence View

        10         20         30         40         50         60 
MRVFCVGLLL FSVTWAAPTF QPQTEKTKQS CVEEQRQEEK NKDNIGFHHL GKRINQELSS 
        70         80         90        100        110        120 
KENIVQERKK DLSLSEASEN KGSSKSQNYF TNRQRLNKEY SISNKENTHN GLRMSIYPKS 
       130        140        150        160        170        180 
TGNKGFEDGD DAISKLHDQE EYGAALIRNN MQHIMGPVTA IKLLGEENKE NTPRNVLNII 
       190        200        210        220        230        240 
PASMNYAKAH SKDKKKPQRD SQAQKSPVKS KSTHRIQHNI DYLKHLSKVK KIPSDFEGSG 
       250        260        270        280        290        300 
YTDLQERGDN DISPFSGDGQ PFKDIPGKGE ATGPDLEGKD IQTGFAGPSE AESTHLDTKK 
       310        320        330        340        350        360 
PGYNEIPERE ENGGNTIGTR DETAKEADAV DVSLVEGSND IMGSTNFKEL PGREGNRVDA 
       370        380        390        400        410        420 
GSQNAHQGKV EFHYPPAPSK EKRKEGSSDA AESTNYNEIP KNGKGSTRKG VDHSNRNQAT 
       430        440        450        460        470        480 
LNEKQRFPSK GKSQGLPIPS RGLDNEIKNE MDSFNGPSHE NIITHGRKYH YVPHRQNNST 
       490        500        510        520    
RNKGMPQGKG SWGRQPHSNR RFSSRRRDDS SESSDSGSSS ESDGD         10         20         30         40         50         60 
MRVFCVGLLL FSVTWAAPTF QPQTEKTKQS CVEEQRQEEK NKDNIGFHHL GKRINQELSS 
        70         80         90        100        110        120 
KENIVQERKK DLSLSEASEN KGSSKSQNYF TNRQRLNKEY SISNKENTHN GLRMSIYPKS 
       130        140        150        160        170        180 
TGNKGFEDGD DAISKLHDQE EYGAALIRNN MQHIMGPVTA IKLLGEENKE NTPRNVLNII 
       190        200        210        220        230        240 
PASMNYAKAH SKDKKKPQRD SQAQKSPVKS KSTHRIQHNI DYLKHLSKVK KIPSDFEGSG 
       250        260        270        280        290        300 
YTDLQERGDN DISPFSGDGQ PFKDIPGKGE ATGPDLEGKD IQTGFAGPSE AESTHLDTKK 
       310        320        330        340        350        360 
PGYNEIPERE ENGGNTIGTR DETAKEADAV DVSLVEGSND IMGSTNFKEL PGREGNRVDA 
       370        380        390        400        410        420 
GSQNAHQGKV EFHYPPAPSK EKRKEGSSDA AESTNYNEIP KNGKGSTRKG VDHSNRNQAT 
       430        440        450        460        470        480 
LNEKQRFPSK GKSQGLPIPS RGLDNEIKNE MDSFNGPSHE NIITHGRKYH YVPHRQNNST 
       490        500        510        520    
RNKGMPQGKG SWGRQPHSNR RFSSRRRDDS SESSDSGSSS ESDGD



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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9NQ76-1-unknown MRVFCV... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt80898
    Q9NQ76-18-unknown PTFQPQ... 18 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9NQ76-114-unknown MSIYPK... 114 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt80899
    Q9NQ76-114-unknown MSIYPK... 114 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt95917

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)