Q9NQ94: APOBEC1 complementation factor

General Information

Protein names	- APOBEC1 complementation factor - APOBEC1-stimulating protein
Gene names	A1CF
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9NQ94

2 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of APOBEC1 complementation factor - Isoform 3 of APOBEC1 complementation factor - Isoform 4 of APOBEC1 complementation factor - Isoform 5 of APOBEC1 complementation factor - Isoform 6 of APOBEC1 complementation factor

Sequence View

        10         20         30         40         50         60
MESNHKSGDG LSGTQKEAAL RALVQRTGYS LVQENGQRKY GGPPPGWDAA PPERGCEIFI
        70         80         90        100        110        120
GKLPRDLFED ELIPLCEKIG KIYEMRMMMD FNGNNRGYAF VTFSNKVEAK NAIKQLNNYE
       130        140        150        160        170        180
IRNGRLLGVC ASVDNCRLFV GGIPKTKKRE EILSEMKKVT EGVVDVIVYP SAADKTKNRG
       190        200        210        220        230        240
FAFVEYESHR AAAMARRKLL PGRIQLWGHG IAVDWAEPEV EVDEDTMSSV KILYVRNLML
       250        260        270        280        290        300
STSEEMIEKE FNNIKPGAVE RVKKIRDYAF VHFSNREDAV EAMKALNGKV LDGSPIEVTL
       310        320        330        340        350        360
AKPVDKDSYV RYTRGTGGRG TMLQGEYTYS LGQVYDPTTT YLGAPVFYAP QTYAAIPSLH
       370        380        390        400        410        420
FPATKGHLSN RAIIRAPSVR EIYMNVPVGA AGVRGLGGRG YLAYTGLGRG YQVKGDKRED
       430        440        450        460        470        480
KLYDILPGME LTPMNPVTLK PQGIKLAPQI LEEICQKNNW GQPVYQLHSA IGQDQRQLFL
       490        500        510        520        530        540
YKITIPALAS QNPAIHPFTP PKLSAFVDEA KTYAAEYTLQ TLGIPTDGGD GTMATAAAAA
       550        560        570        580        590
TAFPGYAVPN ATAPVSAAQL KQAVTLGQDL AAYTTYEVYP TFAVTARGDG YGTF         10         20         30         40         50         60
MESNHKSGDG LSGTQKEAAL RALVQRTGYS LVQENGQRKY GGPPPGWDAA PPERGCEIFI
        70         80         90        100        110        120
GKLPRDLFED ELIPLCEKIG KIYEMRMMMD FNGNNRGYAF VTFSNKVEAK NAIKQLNNYE
       130        140        150        160        170        180
IRNGRLLGVC ASVDNCRLFV GGIPKTKKRE EILSEMKKVT EGVVDVIVYP SAADKTKNRG
       190        200        210        220        230        240
FAFVEYESHR AAAMARRKLL PGRIQLWGHG IAVDWAEPEV EVDEDTMSSV KILYVRNLML
       250        260        270        280        290        300
STSEEMIEKE FNNIKPGAVE RVKKIRDYAF VHFSNREDAV EAMKALNGKV LDGSPIEVTL
       310        320        330        340        350        360
AKPVDKDSYV RYTRGTGGRG TMLQGEYTYS LGQVYDPTTT YLGAPVFYAP QTYAAIPSLH
       370        380        390        400        410        420
FPATKGHLSN RAIIRAPSVR EIYMNVPVGA AGVRGLGGRG YLAYTGLGRG YQVKGDKRED
       430        440        450        460        470        480
KLYDILPGME LTPMNPVTLK PQGIKLAPQI LEEICQKNNW GQPVYQLHSA IGQDQRQLFL
       490        500        510        520        530        540
YKITIPALAS QNPAIHPFTP PKLSAFVDEA KTYAAEYTLQ TLGIPTDGGD GTMATAAAAA
       550        560        570        580        590
TAFPGYAVPN ATAPVSAAQL KQAVTLGQDL AAYTTYEVYP TFAVTARGDG YGTF         10         20         30         40         50         60
MESNHKSGDG LSGTQKEAAL RALVQRTGYS LVQENGQRKY GGPPPGWDAA PPERGCEIFI
        70         80         90        100        110        120
GKLPRDLFED ELIPLCEKIG KIYEMRMMMD FNGNNRGYAF VTFSNKVEAK NAIKQLNNYE
       130        140        150        160        170        180
IRNGRLLGVC ASVDNCRLFV GGIPKTKKRE EILSEMKKVT EGVVDVIVYP SAADKTKNRG
       190        200        210        220        230        240
FAFVEYESHR AAAMARRKLL PGRIQLWGHG IAVDWAEPEV EVDEDTMSSV KILYVRNLML
       250        260        270        280        290        300
STSEEMIEKE FNNIKPGAVE RVKKIRDYAF VHFSNREDAV EAMKALNGKV LDGSPIEVTL
       310        320        330        340        350        360
AKPVDKDSYV RYTRGTGGRG TMLQGEYTYS LGQVYDPTTT YLGAPVFYAP QTYAAIPSLH
       370        380        390        400        410        420
FPATKGHLSN RAIIRAPSVR EIYMNVPVGA AGVRGLGGRG YLAYTGLGRG YQVKGDKRED
       430        440        450        460        470        480
KLYDILPGME LTPMNPVTLK PQGIKLAPQI LEEICQKNNW GQPVYQLHSA IGQDQRQLFL
       490        500        510        520        530        540
YKITIPALAS QNPAIHPFTP PKLSAFVDEA KTYAAEYTLQ TLGIPTDGGD GTMATAAAAA
       550        560        570        580        590
TAFPGYAVPN ATAPVSAAQL KQAVTLGQDL AAYTTYEVYP TFAVTARGDG YGTF         10         20         30         40         50         60
MESNHKSGDG LSGTQKEAAL RALVQRTGYS LVQENGQRKY GGPPPGWDAA PPERGCEIFI
        70         80         90        100        110        120
GKLPRDLFED ELIPLCEKIG KIYEMRMMMD FNGNNRGYAF VTFSNKVEAK NAIKQLNNYE
       130        140        150        160        170        180
IRNGRLLGVC ASVDNCRLFV GGIPKTKKRE EILSEMKKVT EGVVDVIVYP SAADKTKNRG
       190        200        210        220        230        240
FAFVEYESHR AAAMARRKLL PGRIQLWGHG IAVDWAEPEV EVDEDTMSSV KILYVRNLML
       250        260        270        280        290        300
STSEEMIEKE FNNIKPGAVE RVKKIRDYAF VHFSNREDAV EAMKALNGKV LDGSPIEVTL
       310        320        330        340        350        360
AKPVDKDSYV RYTRGTGGRG TMLQGEYTYS LGQVYDPTTT YLGAPVFYAP QTYAAIPSLH
       370        380        390        400        410        420
FPATKGHLSN RAIIRAPSVR EIYMNVPVGA AGVRGLGGRG YLAYTGLGRG YQVKGDKRED
       430        440        450        460        470        480
KLYDILPGME LTPMNPVTLK PQGIKLAPQI LEEICQKNNW GQPVYQLHSA IGQDQRQLFL
       490        500        510        520        530        540
YKITIPALAS QNPAIHPFTP PKLSAFVDEA KTYAAEYTLQ TLGIPTDGGD GTMATAAAAA
       550        560        570        580        590
TAFPGYAVPN ATAPVSAAQL KQAVTLGQDL AAYTTYEVYP TFAVTARGDG YGTF         10         20         30         40         50         60
MESNHKSGDG LSGTQKEAAL RALVQRTGYS LVQENGQRKY GGPPPGWDAA PPERGCEIFI
        70         80         90        100        110        120
GKLPRDLFED ELIPLCEKIG KIYEMRMMMD FNGNNRGYAF VTFSNKVEAK NAIKQLNNYE
       130        140        150        160        170        180
IRNGRLLGVC ASVDNCRLFV GGIPKTKKRE EILSEMKKVT EGVVDVIVYP SAADKTKNRG
       190        200        210        220        230        240
FAFVEYESHR AAAMARRKLL PGRIQLWGHG IAVDWAEPEV EVDEDTMSSV KILYVRNLML
       250        260        270        280        290        300
STSEEMIEKE FNNIKPGAVE RVKKIRDYAF VHFSNREDAV EAMKALNGKV LDGSPIEVTL
       310        320        330        340        350        360
AKPVDKDSYV RYTRGTGGRG TMLQGEYTYS LGQVYDPTTT YLGAPVFYAP QTYAAIPSLH
       370        380        390        400        410        420
FPATKGHLSN RAIIRAPSVR EIYMNVPVGA AGVRGLGGRG YLAYTGLGRG YQVKGDKRED
       430        440        450        460        470        480
KLYDILPGME LTPMNPVTLK PQGIKLAPQI LEEICQKNNW GQPVYQLHSA IGQDQRQLFL
       490        500        510        520        530        540
YKITIPALAS QNPAIHPFTP PKLSAFVDEA KTYAAEYTLQ TLGIPTDGGD GTMATAAAAA
       550        560        570        580        590
TAFPGYAVPN ATAPVSAAQL KQAVTLGQDL AAYTTYEVYP TFAVTARGDG YGTF

Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q9NQ94-1-unknown	MESNHK...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9NQ94-1-unknown	MESNHK...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt65853
Q9NQ94-1-unknown	MESNHK...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt65857
Q9NQ94-85-unknown	MRMMMD...	85	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt65856
Q9NQ94-85-unknown	MRMMMD...	85	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt99402
Q9NQ94-85-unknown	MRMMMD...	85	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt99400
Q9NQ94-85-unknown	MRMMMD...	85	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt99403
Q9NQ94-85-unknown	MRMMMD...	85	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt99401

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...GYGTF	594	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...GYGTF	594	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt61474
...GYGTF	594	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt61475
...GYGTF	594	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt61472
...GYGTF	594	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt61471
...GYGTF	594	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt61473

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

TopFIND

Q9NQ94: APOBEC1 complementation factor

General Information

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates