TopFIND 4.0

Q9NR63: Cytochrome P450 26B1

General Information

Protein names
- Cytochrome P450 26B1
- 1.14.13.- {ECO:0000269|PubMed:10823918, ECO:0000269|PubMed:26937021}
- Cytochrome P450 26A2
- Cytochrome P450 retinoic acid-inactivating 2
- Cytochrome P450RAI-2
- Retinoic acid-metabolizing cytochrome
Gene names CYP26B1
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q9NR63

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MLFEGLDLVS ALATLAACLV SVTLLLAVSQ QLWQLRWAAT RDKSCKLPIP KGSMGFPLIG 
        70         80         90        100        110        120 
ETGHWLLQGS GFQSSRREKY GNVFKTHLLG RPLIRVTGAE NVRKILMGEH HLVSTEWPRS 
       130        140        150        160        170        180 
TRMLLGPNTV SNSIGDIHRN KRKVFSKIFS HEALESYLPK IQLVIQDTLR AWSSHPEAIN 
       190        200        210        220        230        240 
VYQEAQKLTF RMAIRVLLGF SIPEEDLGHL FEVYQQFVDN VFSLPVDLPF SGYRRGIQAR 
       250        260        270        280        290        300 
QILQKGLEKA IREKLQCTQG KDYLDALDLL IESSKEHGKE MTMQELKDGT LELIFAAYAT 
       310        320        330        340        350        360 
TASASTSLIM QLLKHPTVLE KLRDELRAHG ILHSGGCPCE GTLRLDTLSG LRYLDCVIKE 
       370        380        390        400        410        420 
VMRLFTPISG GYRTVLQTFE LDGFQIPKGW SVMYSIRDTH DTAPVFKDVN VFDPDRFSQA 
       430        440        450        460        470        480 
RSEDKDGRFH YLPFGGGVRT CLGKHLAKLF LKVLAVELAS TSRFELATRT FPRITLVPVL 
       490        500        510    
HPVDGLSVKF FGLDSNQNEI LPETEAMLSA TV

Isoforms

- Isoform 2 of Cytochrome P450 26B1 - Isoform 3 of Cytochrome P450 26B1

Sequence View

        10         20         30         40         50         60 
MLFEGLDLVS ALATLAACLV SVTLLLAVSQ QLWQLRWAAT RDKSCKLPIP KGSMGFPLIG 
        70         80         90        100        110        120 
ETGHWLLQGS GFQSSRREKY GNVFKTHLLG RPLIRVTGAE NVRKILMGEH HLVSTEWPRS 
       130        140        150        160        170        180 
TRMLLGPNTV SNSIGDIHRN KRKVFSKIFS HEALESYLPK IQLVIQDTLR AWSSHPEAIN 
       190        200        210        220        230        240 
VYQEAQKLTF RMAIRVLLGF SIPEEDLGHL FEVYQQFVDN VFSLPVDLPF SGYRRGIQAR 
       250        260        270        280        290        300 
QILQKGLEKA IREKLQCTQG KDYLDALDLL IESSKEHGKE MTMQELKDGT LELIFAAYAT 
       310        320        330        340        350        360 
TASASTSLIM QLLKHPTVLE KLRDELRAHG ILHSGGCPCE GTLRLDTLSG LRYLDCVIKE 
       370        380        390        400        410        420 
VMRLFTPISG GYRTVLQTFE LDGFQIPKGW SVMYSIRDTH DTAPVFKDVN VFDPDRFSQA 
       430        440        450        460        470        480 
RSEDKDGRFH YLPFGGGVRT CLGKHLAKLF LKVLAVELAS TSRFELATRT FPRITLVPVL 
       490        500        510    
HPVDGLSVKF FGLDSNQNEI LPETEAMLSA TV         10         20         30         40         50         60 
MLFEGLDLVS ALATLAACLV SVTLLLAVSQ QLWQLRWAAT RDKSCKLPIP KGSMGFPLIG 
        70         80         90        100        110        120 
ETGHWLLQGS GFQSSRREKY GNVFKTHLLG RPLIRVTGAE NVRKILMGEH HLVSTEWPRS 
       130        140        150        160        170        180 
TRMLLGPNTV SNSIGDIHRN KRKVFSKIFS HEALESYLPK IQLVIQDTLR AWSSHPEAIN 
       190        200        210        220        230        240 
VYQEAQKLTF RMAIRVLLGF SIPEEDLGHL FEVYQQFVDN VFSLPVDLPF SGYRRGIQAR 
       250        260        270        280        290        300 
QILQKGLEKA IREKLQCTQG KDYLDALDLL IESSKEHGKE MTMQELKDGT LELIFAAYAT 
       310        320        330        340        350        360 
TASASTSLIM QLLKHPTVLE KLRDELRAHG ILHSGGCPCE GTLRLDTLSG LRYLDCVIKE 
       370        380        390        400        410        420 
VMRLFTPISG GYRTVLQTFE LDGFQIPKGW SVMYSIRDTH DTAPVFKDVN VFDPDRFSQA 
       430        440        450        460        470        480 
RSEDKDGRFH YLPFGGGVRT CLGKHLAKLF LKVLAVELAS TSRFELATRT FPRITLVPVL 
       490        500        510    
HPVDGLSVKF FGLDSNQNEI LPETEAMLSA TV



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Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9NR63-1-unknown MLFEGL... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9NR63-1-unknown MLFEGL... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt71513

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)