TopFIND 4.0

Q9NRG4: N-lysine methyltransferase SMYD2

General Information

Protein names
- N-lysine methyltransferase SMYD2
- 2.1.1.-
- HSKM-B
- Histone methyltransferase SMYD2
- 2.1.1.43
- Lysine N-methyltransferase 3C
- SET and MYND domain-containing protein 2
Gene names SMYD2
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q9NRG4

2

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MRAEGLGGLE RFCSPGKGRG LRALQPFQVG DLLFSCPAYA YVLTVNERGN HCEYCFTRKE 
        70         80         90        100        110        120 
GLSKCGRCKQ AFYCNVECQK EDWPMHKLEC SPMVVFGENW NPSETVRLTA RILAKQKIHP 
       130        140        150        160        170        180 
ERTPSEKLLA VKEFESHLDK LDNEKKDLIQ SDIAALHHFY SKHLGFPDND SLVVLFAQVN 
       190        200        210        220        230        240 
CNGFTIEDEE LSHLGSAIFP DVALMNHSCC PNVIVTYKGT LAEVRAVQEI KPGEEVFTSY 
       250        260        270        280        290        300 
IDLLYPTEDR NDRLRDSYFF TCECQECTTK DKDKAKVEIR KLSDPPKAEA IRDMVRYARN 
       310        320        330        340        350        360 
VIEEFRRAKH YKSPSELLEI CELSQEKMSS VFEDSNVYML HMMYQAMGVC LYMQDWEGAL 
       370        380        390        400        410        420 
QYGQKIIKPY SKHYPLYSLN VASMWLKLGR LYMGLEHKAA GEKALKKAIA IMEVAHGKDH 
       430    
PYISEIKQEI ESH

Isoforms

- Isoform 2 of N-lysine methyltransferase SMYD2

Sequence View

        10         20         30         40         50         60 
MRAEGLGGLE RFCSPGKGRG LRALQPFQVG DLLFSCPAYA YVLTVNERGN HCEYCFTRKE 
        70         80         90        100        110        120 
GLSKCGRCKQ AFYCNVECQK EDWPMHKLEC SPMVVFGENW NPSETVRLTA RILAKQKIHP 
       130        140        150        160        170        180 
ERTPSEKLLA VKEFESHLDK LDNEKKDLIQ SDIAALHHFY SKHLGFPDND SLVVLFAQVN 
       190        200        210        220        230        240 
CNGFTIEDEE LSHLGSAIFP DVALMNHSCC PNVIVTYKGT LAEVRAVQEI KPGEEVFTSY 
       250        260        270        280        290        300 
IDLLYPTEDR NDRLRDSYFF TCECQECTTK DKDKAKVEIR KLSDPPKAEA IRDMVRYARN 
       310        320        330        340        350        360 
VIEEFRRAKH YKSPSELLEI CELSQEKMSS VFEDSNVYML HMMYQAMGVC LYMQDWEGAL 
       370        380        390        400        410        420 
QYGQKIIKPY SKHYPLYSLN VASMWLKLGR LYMGLEHKAA GEKALKKAIA IMEVAHGKDH 
       430    
PYISEIKQEI ESH



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Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)