Q9NRS4: Transmembrane protease serine 4

General Information

Protein names	- Transmembrane protease serine 4 - 3.4.21.- - Channel-activating protease 2 - CAPH2 - Membrane-type serine protease 2 - MT-SP2
Gene names	TMPRSS4
Organism	Homo sapiens
Protease Family
Protease ID	S01.034
Chromosome location
UniProt ID	Q9NRS4

1 N-termini

3 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Transmembrane protease serine 4 - Isoform 3 of Transmembrane protease serine 4 - Isoform 4 of Transmembrane protease serine 4

Sequence View

        10         20         30         40         50         60
MLQDPDSDQP LNSLDVKPLR KPRIPMETFR KVGIPIIIAL LSLASIIIVV VLIKVILDKY
        70         80         90        100        110        120
YFLCGQPLHF IPRKQLCDGE LDCPLGEDEE HCVKSFPEGP AVAVRLSKDR STLQVLDSAT
       130        140        150        160        170        180
GNWFSACFDN FTEALAETAC RQMGYSSKPT FRAVEIGPDQ DLDVVEITEN SQELRMRNSS
       190        200        210        220        230        240
GPCLSGSLVS LHCLACGKSL KTPRVVGVEE ASVDSWPWQV SIQYDKQHVC GGSILDPHWV
       250        260        270        280        290        300
LTAAHCFRKH TDVFNWKVRA GSDKLGSFPS LAVAKIIIIE FNPMYPKDND IALMKLQFPL
       310        320        330        340        350        360
TFSGTVRPIC LPFFDEELTP ATPLWIIGWG FTKQNGGKMS DILLQASVQV IDSTRCNADD
       370        380        390        400        410        420
AYQGEVTEKM MCAGIPEGGV DTCQGDSGGP LMYQSDQWHV VGIVSWGYGC GGPSTPGVYT
       430
KVSAYLNWIY NVWKAEL         10         20         30         40         50         60
MLQDPDSDQP LNSLDVKPLR KPRIPMETFR KVGIPIIIAL LSLASIIIVV VLIKVILDKY
        70         80         90        100        110        120
YFLCGQPLHF IPRKQLCDGE LDCPLGEDEE HCVKSFPEGP AVAVRLSKDR STLQVLDSAT
       130        140        150        160        170        180
GNWFSACFDN FTEALAETAC RQMGYSSKPT FRAVEIGPDQ DLDVVEITEN SQELRMRNSS
       190        200        210        220        230        240
GPCLSGSLVS LHCLACGKSL KTPRVVGVEE ASVDSWPWQV SIQYDKQHVC GGSILDPHWV
       250        260        270        280        290        300
LTAAHCFRKH TDVFNWKVRA GSDKLGSFPS LAVAKIIIIE FNPMYPKDND IALMKLQFPL
       310        320        330        340        350        360
TFSGTVRPIC LPFFDEELTP ATPLWIIGWG FTKQNGGKMS DILLQASVQV IDSTRCNADD
       370        380        390        400        410        420
AYQGEVTEKM MCAGIPEGGV DTCQGDSGGP LMYQSDQWHV VGIVSWGYGC GGPSTPGVYT
       430
KVSAYLNWIY NVWKAEL         10         20         30         40         50         60
MLQDPDSDQP LNSLDVKPLR KPRIPMETFR KVGIPIIIAL LSLASIIIVV VLIKVILDKY
        70         80         90        100        110        120
YFLCGQPLHF IPRKQLCDGE LDCPLGEDEE HCVKSFPEGP AVAVRLSKDR STLQVLDSAT
       130        140        150        160        170        180
GNWFSACFDN FTEALAETAC RQMGYSSKPT FRAVEIGPDQ DLDVVEITEN SQELRMRNSS
       190        200        210        220        230        240
GPCLSGSLVS LHCLACGKSL KTPRVVGVEE ASVDSWPWQV SIQYDKQHVC GGSILDPHWV
       250        260        270        280        290        300
LTAAHCFRKH TDVFNWKVRA GSDKLGSFPS LAVAKIIIIE FNPMYPKDND IALMKLQFPL
       310        320        330        340        350        360
TFSGTVRPIC LPFFDEELTP ATPLWIIGWG FTKQNGGKMS DILLQASVQV IDSTRCNADD
       370        380        390        400        410        420
AYQGEVTEKM MCAGIPEGGV DTCQGDSGGP LMYQSDQWHV VGIVSWGYGC GGPSTPGVYT
       430
KVSAYLNWIY NVWKAEL

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

1 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9NRS4-1-unknown	MLQDPD...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9NRS4-1-unknown	MLQDPD...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt92545

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...RNSSGP	181	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000429833
...RNSSGP	181	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155408
...RNSSGP	181	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155410
...RNSSGP	181	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155409
...IQYDKQ	226	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000428407
...WKAEL	437	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...WKAEL	437	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt88165
...WKAEL	437	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt88163
...WKAEL	437	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt88164

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)