Q9NS91: E3 ubiquitin-protein ligase RAD18

General Information

Protein names	- E3 ubiquitin-protein ligase RAD18 - 2.3.2.27 - Postreplication repair protein RAD18 - hHR18 - hRAD18 - RING finger protein 73 - RING-type E3 ubiquitin transferase RAD18 {ECO:0000305}
Gene names	RAD18
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9NS91

2 N-termini

3 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MDSLAESRWP PGLAVMKTID DLLRCGICFE YFNIAMIIPQ CSHNYCSLCI RKFLSYKTQC
        70         80         90        100        110        120
PTCCVTVTEP DLKNNRILDE LVKSLNFARN HLLQFALESP AKSPASSSSK NLAVKVYTPV
       130        140        150        160        170        180
ASRQSLKQGS RLMDNFLIRE MSGSTSELLI KENKSKFSPQ KEASPAAKTK ETRSVEEIAP
       190        200        210        220        230        240
DPSEAKRPEP PSTSTLKQVT KVDCPVCGVN IPESHINKHL DSCLSREEKK ESLRSSVHKR
       250        260        270        280        290        300
KPLPKTVYNL LSDRDLKKKL KEHGLSIQGN KQQLIKRHQE FVHMYNAQCD ALHPKSAAEI
       310        320        330        340        350        360
VREIENIEKT RMRLEASKLN ESVMVFTKDQ TEKEIDEIHS KYRKKHKSEF QLLVDQARKG
       370        380        390        400        410        420
YKKIAGMSQK TVTITKEDES TEKLSSVCMG QEDNMTSVTN HFSQSKLDSP EELEPDREED
       430        440        450        460        470        480
SSSCIDIQEV LSSSESDSCN SSSSDIIRDL LEEEEAWEAS HKNDLQDTEI SPRQNRRTRA
       490
AESAEIEPRN KRNRN

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9NS91-1-Acetylation	MDSLAE...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9NS91-1-Acetylation	MDSLAE...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q9NS91-1-Acetylation	MDSLAE...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q9NS91-384-unknown	LSSVCM...	384		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000393783

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...FARNHL	91	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000412261
...EASHKN	462	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000393783
...KRNRN	495	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)