TopFIND 4.0

Q9NSE2: Cytokine-inducible SH2-containing protein

General Information

Protein names
- Cytokine-inducible SH2-containing protein
- CIS
- CIS-1
- Protein G18
- Suppressor of cytokine signaling
- SOCS
Gene names CISH
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q9NSE2

3

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MVLCVQGPRP LLAVERTGQR PLWAPSLELP KPVMQPLPAG AFLEEVAEGT PAQTESEPKV 
        70         80         90        100        110        120 
LDPEEDLLCI AKTFSYLRES GWYWGSITAS EARQHLQKMP EGTFLVRDST HPSYLFTLSV 
       130        140        150        160        170        180 
KTTRGPTNVR IEYADSSFRL DSNCLSRPRI LAFPDVVSLV QHYVASCTAD TRSDSPDPAP 
       190        200        210        220        230        240 
TPALPMPKED APSDPALPAP PPATAVHLKL VQPFVRRSSA RSLQHLCRLV INRLVADVDC 
       250    
LPLPRRMADY LRQYPFQL

Isoforms

- Isoform 1B of Cytokine-inducible SH2-containing protein - Isoform 1C of Cytokine-inducible SH2-containing protein

Sequence View

        10         20         30         40         50         60 
MVLCVQGPRP LLAVERTGQR PLWAPSLELP KPVMQPLPAG AFLEEVAEGT PAQTESEPKV 
        70         80         90        100        110        120 
LDPEEDLLCI AKTFSYLRES GWYWGSITAS EARQHLQKMP EGTFLVRDST HPSYLFTLSV 
       130        140        150        160        170        180 
KTTRGPTNVR IEYADSSFRL DSNCLSRPRI LAFPDVVSLV QHYVASCTAD TRSDSPDPAP 
       190        200        210        220        230        240 
TPALPMPKED APSDPALPAP PPATAVHLKL VQPFVRRSSA RSLQHLCRLV INRLVADVDC 
       250    
LPLPRRMADY LRQYPFQL         10         20         30         40         50         60 
MVLCVQGPRP LLAVERTGQR PLWAPSLELP KPVMQPLPAG AFLEEVAEGT PAQTESEPKV 
        70         80         90        100        110        120 
LDPEEDLLCI AKTFSYLRES GWYWGSITAS EARQHLQKMP EGTFLVRDST HPSYLFTLSV 
       130        140        150        160        170        180 
KTTRGPTNVR IEYADSSFRL DSNCLSRPRI LAFPDVVSLV QHYVASCTAD TRSDSPDPAP 
       190        200        210        220        230        240 
TPALPMPKED APSDPALPAP PPATAVHLKL VQPFVRRSSA RSLQHLCRLV INRLVADVDC 
       250    
LPLPRRMADY LRQYPFQL



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)