Q9NT68: Teneurin-2
| Protein names | - Teneurin-2 - Ten-2 - Protein Odd Oz/ten-m homolog 2 - Tenascin-M2 - Ten-m2 - Teneurin transmembrane protein 2 - Ten-2, soluble form - Ten-2 intracellular domain - Ten-2 ICD |
|---|---|
| Gene names | TENM2 |
| Organism | Homo sapiens |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | Q9NT68 |
2
N-termini
2
C-termini
0
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MDVKDRRHRS LTRGRCGKEC RYTSSSLDSE DCRVPTQKSY SSSETLKAYD HDSRMHYGNR
70 80 90 100 110 120
VTDLIHRESD EFPRQGTNFT LAELGICEPS PHRSGYCSDM GILHQGYSLS TGSDADSDTE
130 140 150 160 170 180
GGMSPEHAIR LWGRGIKSRR SSGLSSRENS ALTLTDSDNE NKSDDENGRP IPPTSSPSLL
190 200 210 220 230 240
PSAQLPSSHN PPPVSCQMPL LDSNTSHQIM DTNPDEEFSP NSYLLRACSG PQQASSSGPP
250 260 270 280 290 300
NHHSQSTLRP PLPPPHNHTL SHHHSSANSL NRNSLTNRRS QIHAPAPAPN DLATTPESVQ
310 320 330 340 350 360
LQDSWVLNSN VPLETRHFLF KTSSGSTPLF SSSSPGYPLT SGTVYTPPPR LLPRNTFSRK
370 380 390 400 410 420
AFKLKKPSKY CSWKCAALSA IAAALLLAIL LAYFIAMHLL GLNWQLQPAD GHTFNNGIRT
430 440 450 460 470 480
GLPGNDDVAT MPSGGKVPWS LKNSSIDSGE AEVGRRVTQE VPPGVFWRSQ IHISQPQFLK
490 500 510 520 530 540
FNISLGKDAL FGVYIRRGLP PSHAQYDFME RLDGKEKWSV VESPRERRSI QTLVQNEAVF
550 560 570 580 590 600
VQYLDVGLWH LAFYNDGKDK EMVSFNTVVL DSVQDCPRNC HGNGECVSGV CHCFPGFLGA
610 620 630 640 650 660
DCAKAACPVL CSGNGQYSKG TCQCYSGWKG AECDVPMNQC IDPSCGGHGS CIDGNCVCSA
670 680 690 700 710 720
GYKGEHCEEV DCLDPTCSSH GVCVNGECLC SPGWGGLNCE LARVQCPDQC SGHGTYLPDT
730 740 750 760 770 780
GLCSCDPNWM GPDCSVEVCS VDCGTHGVCI GGACRCEEGW TGAACDQRVC HPRCIEHGTC
790 800 810 820 830 840
KDGKCECREG WNGEHCTIGR QTAGTETDGC PDLCNGNGRC TLGQNSWQCV CQTGWRGPGC
850 860 870 880 890 900
NVAMETSCAD NKDNEGDGLV DCLDPDCCLQ SACQNSLLCR GSRDPLDIIQ QGQTDWPAVK
910 920 930 940 950 960
SFYDRIKLLA GKDSTHIIPG ENPFNSSLVS LIRGQVVTTD GTPLVGVNVS FVKYPKYGYT
970 980 990 1000 1010 1020
ITRQDGTFDL IANGGASLTL HFERAPFMSQ ERTVWLPWNS FYAMDTLVMK TEENSIPSCD
1030 1040 1050 1060 1070 1080
LSGFVRPDPI IISSPLSTFF SAAPGQNPIV PETQVLHEEI ELPGSNVKLR YLSSRTAGYK
1090 1100 1110 1120 1130 1140
SLLKITMTQS TVPLNLIRVH LMVAVEGHLF QKSFQASPNL AYTFIWDKTD AYGQRVYGLS
1150 1160 1170 1180 1190 1200
DAVVSVGFEY ETCPSLILWE KRTALLQGFE LDPSNLGGWS LDKHHILNVK SGILHKGTGE
1210 1220 1230 1240 1250 1260
NQFLTQQPAI ITSIMGNGRR RSISCPSCNG LAEGNKLLAP VALAVGIDGS LYVGDFNYIR
1270 1280 1290 1300 1310 1320
RIFPSRNVTS ILELRNKEFK HSNNPAHKYY LAVDPVSGSL YVSDTNSRRI YRVKSLSGTK
1330 1340 1350 1360 1370 1380
DLAGNSEVVA GTGEQCLPFD EARCGDGGKA IDATLMSPRG IAVDKNGLMY FVDATMIRKV
1390 1400 1410 1420 1430 1440
DQNGIISTLL GSNDLTAVRP LSCDSSMDVA QVRLEWPTDL AVNPMDNSLY VLENNVILRI
1450 1460 1470 1480 1490 1500
TENHQVSIIA GRPMHCQVPG IDYSLSKLAI HSALESASAI AISHTGVLYI TETDEKKINR
1510 1520 1530 1540 1550 1560
LRQVTTNGEI CLLAGAASDC DCKNDVNCNC YSGDDAYATD AILNSPSSLA VAPDGTIYIA
1570 1580 1590 1600 1610 1620
DLGNIRIRAV SKNKPVLNAF NQYEAASPGE QELYVFNADG IHQYTVSLVT GEYLYNFTYS
1630 1640 1650 1660 1670 1680
TDNDVTELID NNGNSLKIRR DSSGMPRHLL MPDNQIITLT VGTNGGLKVV STQNLELGLM
1690 1700 1710 1720 1730 1740
TYDGNTGLLA TKSDETGWTT FYDYDHEGRL TNVTRPTGVV TSLHREMEKS ITIDIENSNR
1750 1760 1770 1780 1790 1800
DDDVTVITNL SSVEASYTVV QDQVRNSYQL CNNGTLRVMY ANGMGISFHS EPHVLAGTIT
1810 1820 1830 1840 1850 1860
PTIGRCNISL PMENGLNSIE WRLRKEQIKG KVTIFGRKLR VHGRNLLSID YDRNIRTEKI
1870 1880 1890 1900 1910 1920
YDDHRKFTLR IIYDQVGRPF LWLPSSGLAA VNVSYFFNGR LAGLQRGAMS ERTDIDKQGR
1930 1940 1950 1960 1970 1980
IVSRMFADGK VWSYSYLDKS MVLLLQSQRQ YIFEYDSSDR LLAVTMPSVA RHSMSTHTSI
1990 2000 2010 2020 2030 2040
GYIRNIYNPP ESNASVIFDY SDDGRILKTS FLGTGRQVFY KYGKLSKLSE IVYDSTAVTF
2050 2060 2070 2080 2090 2100
GYDETTGVLK MVNLQSGGFS CTIRYRKIGP LVDKQIYRFS EEGMVNARFD YTYHDNSFRI
2110 2120 2130 2140 2150 2160
ASIKPVISET PLPVDLYRYD EISGKVEHFG KFGVIYYDIN QIITTAVMTL SKHFDTHGRI
2170 2180 2190 2200 2210 2220
KEVQYEMFRS LMYWMTVQYD SMGRVIKREL KLGPYANTTK YTYDYDGDGQ LQSVAVNDRP
2230 2240 2250 2260 2270 2280
TWRYSYDLNG NLHLLNPGNS VRLMPLRYDL RDRITRLGDV QYKIDDDGYL CQRGSDIFEY
2290 2300 2310 2320 2330 2340
NSKGLLTRAY NKASGWSVQY RYDGVGRRAS YKTNLGHHLQ YFYSDLHNPT RITHVYNHSN
2350 2360 2370 2380 2390 2400
SEITSLYYDL QGHLFAMESS SGEEYYVASD NTGTPLAVFS INGLMIKQLQ YTAYGEIYYD
2410 2420 2430 2440 2450 2460
SNPDFQMVIG FHGGLYDPLT KLVHFTQRDY DVLAGRWTSP DYTMWKNVGK EPAPFNLYMF
2470 2480 2490 2500 2510 2520
KSNNPLSSEL DLKNYVTDVK SWLVMFGFQL SNIIPGFPRA KMYFVPPPYE LSESQASENG
2530 2540 2550 2560 2570 2580
QLITGVQQTT ERHNQAFMAL EGQVITKKLH ASIREKAGHW FATTTPIIGK GIMFAIKEGR
2590 2600 2610 2620 2630 2640
VTTGVSSIAS EDSRKVASVL NNAYYLDKMH YSIEGKDTHY FVKIGSADGD LVTLGTTIGR
2650 2660 2670 2680 2690 2700
KVLESGVNVT VSQPTLLVNG RTRRFTNIEF QYSTLLLSIR YGLTPDTLDE EKARVLDQAR
2710 2720 2730 2740 2750 2760
QRALGTAWAK EQQKARDGRE GSRLWTEGEK QQLLSTGRVQ GYEGYYVLPV EQYPELADSS
2770
SNIQFLRQNE MGKR
Isoforms
- Isoform 2 of Teneurin-2Sequence View
10 20 30 40 50 60
MDVKDRRHRS LTRGRCGKEC RYTSSSLDSE DCRVPTQKSY SSSETLKAYD HDSRMHYGNR
70 80 90 100 110 120
VTDLIHRESD EFPRQGTNFT LAELGICEPS PHRSGYCSDM GILHQGYSLS TGSDADSDTE
130 140 150 160 170 180
GGMSPEHAIR LWGRGIKSRR SSGLSSRENS ALTLTDSDNE NKSDDENGRP IPPTSSPSLL
190 200 210 220 230 240
PSAQLPSSHN PPPVSCQMPL LDSNTSHQIM DTNPDEEFSP NSYLLRACSG PQQASSSGPP
250 260 270 280 290 300
NHHSQSTLRP PLPPPHNHTL SHHHSSANSL NRNSLTNRRS QIHAPAPAPN DLATTPESVQ
310 320 330 340 350 360
LQDSWVLNSN VPLETRHFLF KTSSGSTPLF SSSSPGYPLT SGTVYTPPPR LLPRNTFSRK
370 380 390 400 410 420
AFKLKKPSKY CSWKCAALSA IAAALLLAIL LAYFIAMHLL GLNWQLQPAD GHTFNNGIRT
430 440 450 460 470 480
GLPGNDDVAT MPSGGKVPWS LKNSSIDSGE AEVGRRVTQE VPPGVFWRSQ IHISQPQFLK
490 500 510 520 530 540
FNISLGKDAL FGVYIRRGLP PSHAQYDFME RLDGKEKWSV VESPRERRSI QTLVQNEAVF
550 560 570 580 590 600
VQYLDVGLWH LAFYNDGKDK EMVSFNTVVL DSVQDCPRNC HGNGECVSGV CHCFPGFLGA
610 620 630 640 650 660
DCAKAACPVL CSGNGQYSKG TCQCYSGWKG AECDVPMNQC IDPSCGGHGS CIDGNCVCSA
670 680 690 700 710 720
GYKGEHCEEV DCLDPTCSSH GVCVNGECLC SPGWGGLNCE LARVQCPDQC SGHGTYLPDT
730 740 750 760 770 780
GLCSCDPNWM GPDCSVEVCS VDCGTHGVCI GGACRCEEGW TGAACDQRVC HPRCIEHGTC
790 800 810 820 830 840
KDGKCECREG WNGEHCTIGR QTAGTETDGC PDLCNGNGRC TLGQNSWQCV CQTGWRGPGC
850 860 870 880 890 900
NVAMETSCAD NKDNEGDGLV DCLDPDCCLQ SACQNSLLCR GSRDPLDIIQ QGQTDWPAVK
910 920 930 940 950 960
SFYDRIKLLA GKDSTHIIPG ENPFNSSLVS LIRGQVVTTD GTPLVGVNVS FVKYPKYGYT
970 980 990 1000 1010 1020
ITRQDGTFDL IANGGASLTL HFERAPFMSQ ERTVWLPWNS FYAMDTLVMK TEENSIPSCD
1030 1040 1050 1060 1070 1080
LSGFVRPDPI IISSPLSTFF SAAPGQNPIV PETQVLHEEI ELPGSNVKLR YLSSRTAGYK
1090 1100 1110 1120 1130 1140
SLLKITMTQS TVPLNLIRVH LMVAVEGHLF QKSFQASPNL AYTFIWDKTD AYGQRVYGLS
1150 1160 1170 1180 1190 1200
DAVVSVGFEY ETCPSLILWE KRTALLQGFE LDPSNLGGWS LDKHHILNVK SGILHKGTGE
1210 1220 1230 1240 1250 1260
NQFLTQQPAI ITSIMGNGRR RSISCPSCNG LAEGNKLLAP VALAVGIDGS LYVGDFNYIR
1270 1280 1290 1300 1310 1320
RIFPSRNVTS ILELRNKEFK HSNNPAHKYY LAVDPVSGSL YVSDTNSRRI YRVKSLSGTK
1330 1340 1350 1360 1370 1380
DLAGNSEVVA GTGEQCLPFD EARCGDGGKA IDATLMSPRG IAVDKNGLMY FVDATMIRKV
1390 1400 1410 1420 1430 1440
DQNGIISTLL GSNDLTAVRP LSCDSSMDVA QVRLEWPTDL AVNPMDNSLY VLENNVILRI
1450 1460 1470 1480 1490 1500
TENHQVSIIA GRPMHCQVPG IDYSLSKLAI HSALESASAI AISHTGVLYI TETDEKKINR
1510 1520 1530 1540 1550 1560
LRQVTTNGEI CLLAGAASDC DCKNDVNCNC YSGDDAYATD AILNSPSSLA VAPDGTIYIA
1570 1580 1590 1600 1610 1620
DLGNIRIRAV SKNKPVLNAF NQYEAASPGE QELYVFNADG IHQYTVSLVT GEYLYNFTYS
1630 1640 1650 1660 1670 1680
TDNDVTELID NNGNSLKIRR DSSGMPRHLL MPDNQIITLT VGTNGGLKVV STQNLELGLM
1690 1700 1710 1720 1730 1740
TYDGNTGLLA TKSDETGWTT FYDYDHEGRL TNVTRPTGVV TSLHREMEKS ITIDIENSNR
1750 1760 1770 1780 1790 1800
DDDVTVITNL SSVEASYTVV QDQVRNSYQL CNNGTLRVMY ANGMGISFHS EPHVLAGTIT
1810 1820 1830 1840 1850 1860
PTIGRCNISL PMENGLNSIE WRLRKEQIKG KVTIFGRKLR VHGRNLLSID YDRNIRTEKI
1870 1880 1890 1900 1910 1920
YDDHRKFTLR IIYDQVGRPF LWLPSSGLAA VNVSYFFNGR LAGLQRGAMS ERTDIDKQGR
1930 1940 1950 1960 1970 1980
IVSRMFADGK VWSYSYLDKS MVLLLQSQRQ YIFEYDSSDR LLAVTMPSVA RHSMSTHTSI
1990 2000 2010 2020 2030 2040
GYIRNIYNPP ESNASVIFDY SDDGRILKTS FLGTGRQVFY KYGKLSKLSE IVYDSTAVTF
2050 2060 2070 2080 2090 2100
GYDETTGVLK MVNLQSGGFS CTIRYRKIGP LVDKQIYRFS EEGMVNARFD YTYHDNSFRI
2110 2120 2130 2140 2150 2160
ASIKPVISET PLPVDLYRYD EISGKVEHFG KFGVIYYDIN QIITTAVMTL SKHFDTHGRI
2170 2180 2190 2200 2210 2220
KEVQYEMFRS LMYWMTVQYD SMGRVIKREL KLGPYANTTK YTYDYDGDGQ LQSVAVNDRP
2230 2240 2250 2260 2270 2280
TWRYSYDLNG NLHLLNPGNS VRLMPLRYDL RDRITRLGDV QYKIDDDGYL CQRGSDIFEY
2290 2300 2310 2320 2330 2340
NSKGLLTRAY NKASGWSVQY RYDGVGRRAS YKTNLGHHLQ YFYSDLHNPT RITHVYNHSN
2350 2360 2370 2380 2390 2400
SEITSLYYDL QGHLFAMESS SGEEYYVASD NTGTPLAVFS INGLMIKQLQ YTAYGEIYYD
2410 2420 2430 2440 2450 2460
SNPDFQMVIG FHGGLYDPLT KLVHFTQRDY DVLAGRWTSP DYTMWKNVGK EPAPFNLYMF
2470 2480 2490 2500 2510 2520
KSNNPLSSEL DLKNYVTDVK SWLVMFGFQL SNIIPGFPRA KMYFVPPPYE LSESQASENG
2530 2540 2550 2560 2570 2580
QLITGVQQTT ERHNQAFMAL EGQVITKKLH ASIREKAGHW FATTTPIIGK GIMFAIKEGR
2590 2600 2610 2620 2630 2640
VTTGVSSIAS EDSRKVASVL NNAYYLDKMH YSIEGKDTHY FVKIGSADGD LVTLGTTIGR
2650 2660 2670 2680 2690 2700
KVLESGVNVT VSQPTLLVNG RTRRFTNIEF QYSTLLLSIR YGLTPDTLDE EKARVLDQAR
2710 2720 2730 2740 2750 2760
QRALGTAWAK EQQKARDGRE GSRLWTEGEK QQLLSTGRVQ GYEGYYVLPV EQYPELADSS
2770
SNIQFLRQNE MGKR
Protein Neighborhood
Domains & Features
2 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| Q9NT68-1-unknown | MDVKDR... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| Q9NT68-1-unknown | MDVKDR... | 1 | inferred from similarity | unknown | UniProtKB | inferred from uniprot (by similarity) | |||
| Q9NT68-529-unknown | SIQTLV... | 529 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| Q9NT68-529-unknown | SIQTLV... | 529 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt116231 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ... | 0 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| ...EMGKR | 2774 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| ...EMGKR | 2774 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt87461 |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|