TopFIND 4.0

Q9NUG4: Cerebral cavernous malformations 2 protein-like

General Information

Protein names
- Cerebral cavernous malformations 2 protein-like
- CCM2-like
Gene names CCM2L
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q9NUG4

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MEYEVKKGKK GFVSPIRRLV FPKAGRRAAC RSSVSRRPLH SMPLYPPDYL IDPQILLCDY 
        70         80         90        100        110        120 
LEKEVKFLGH LTWVTSSLNP SSRDELLQLL DTARQLKELP LKTTAEQDSI LSLSARCLLL 
       130        140        150        160        170        180 
TWRDNEELIL RIPTHEIAAA SYLQDDALHL LVLKTGLGVD PVPAGVDASP GGAGRDPGPP 
       190        200        210        220        230        240 
GGAPEKRRVG TAERRHTICS LDWRMGWGGG AAEARAGGGG GGSLERQRAG ARASGSWERR 
       250        260        270        280        290        300 
QTFSGSWERR HGGGGGGGGA GKPGGSWERR QAGSGGGGSW ERRHPGPNPL DPQDPSPDAY 
       310        320        330        340        350        360 
CNLVILAVAN RDAAEESCAL ICQVFQIIYG DQSIECVDRA GYHYTSTPER PWLCSRSESC 
       370        380        390        400        410        420 
HTDGTYAYDA DFSCCSSFNG SQDTFEACYS GTSTPSFHGS HCSGSDHSSL GLEQLQDYMV 
       430        440        450        460        470        480 
TLRSKLGPLE IQQFAMLLRE YRLGLPIQDY CTGLLKLYGD RRKFLLLGMR PFIPDQDIGY 
       490        500        510        520        530        540 
FEGFLEGVGI REGGILTDSF GRIKRSMSST SASAVRSYDG AAQRPEAQAF HRLLADITHD 
       550        560        570    
IEALAPDDDD DDEDEPRGSR GGSDAAEDNY L

Isoforms

- Isoform 2 of Cerebral cavernous malformations 2 protein-like - Isoform 3 of Cerebral cavernous malformations 2 protein-like

Sequence View

        10         20         30         40         50         60 
MEYEVKKGKK GFVSPIRRLV FPKAGRRAAC RSSVSRRPLH SMPLYPPDYL IDPQILLCDY 
        70         80         90        100        110        120 
LEKEVKFLGH LTWVTSSLNP SSRDELLQLL DTARQLKELP LKTTAEQDSI LSLSARCLLL 
       130        140        150        160        170        180 
TWRDNEELIL RIPTHEIAAA SYLQDDALHL LVLKTGLGVD PVPAGVDASP GGAGRDPGPP 
       190        200        210        220        230        240 
GGAPEKRRVG TAERRHTICS LDWRMGWGGG AAEARAGGGG GGSLERQRAG ARASGSWERR 
       250        260        270        280        290        300 
QTFSGSWERR HGGGGGGGGA GKPGGSWERR QAGSGGGGSW ERRHPGPNPL DPQDPSPDAY 
       310        320        330        340        350        360 
CNLVILAVAN RDAAEESCAL ICQVFQIIYG DQSIECVDRA GYHYTSTPER PWLCSRSESC 
       370        380        390        400        410        420 
HTDGTYAYDA DFSCCSSFNG SQDTFEACYS GTSTPSFHGS HCSGSDHSSL GLEQLQDYMV 
       430        440        450        460        470        480 
TLRSKLGPLE IQQFAMLLRE YRLGLPIQDY CTGLLKLYGD RRKFLLLGMR PFIPDQDIGY 
       490        500        510        520        530        540 
FEGFLEGVGI REGGILTDSF GRIKRSMSST SASAVRSYDG AAQRPEAQAF HRLLADITHD 
       550        560        570    
IEALAPDDDD DDEDEPRGSR GGSDAAEDNY L         10         20         30         40         50         60 
MEYEVKKGKK GFVSPIRRLV FPKAGRRAAC RSSVSRRPLH SMPLYPPDYL IDPQILLCDY 
        70         80         90        100        110        120 
LEKEVKFLGH LTWVTSSLNP SSRDELLQLL DTARQLKELP LKTTAEQDSI LSLSARCLLL 
       130        140        150        160        170        180 
TWRDNEELIL RIPTHEIAAA SYLQDDALHL LVLKTGLGVD PVPAGVDASP GGAGRDPGPP 
       190        200        210        220        230        240 
GGAPEKRRVG TAERRHTICS LDWRMGWGGG AAEARAGGGG GGSLERQRAG ARASGSWERR 
       250        260        270        280        290        300 
QTFSGSWERR HGGGGGGGGA GKPGGSWERR QAGSGGGGSW ERRHPGPNPL DPQDPSPDAY 
       310        320        330        340        350        360 
CNLVILAVAN RDAAEESCAL ICQVFQIIYG DQSIECVDRA GYHYTSTPER PWLCSRSESC 
       370        380        390        400        410        420 
HTDGTYAYDA DFSCCSSFNG SQDTFEACYS GTSTPSFHGS HCSGSDHSSL GLEQLQDYMV 
       430        440        450        460        470        480 
TLRSKLGPLE IQQFAMLLRE YRLGLPIQDY CTGLLKLYGD RRKFLLLGMR PFIPDQDIGY 
       490        500        510        520        530        540 
FEGFLEGVGI REGGILTDSF GRIKRSMSST SASAVRSYDG AAQRPEAQAF HRLLADITHD 
       550        560        570    
IEALAPDDDD DDEDEPRGSR GGSDAAEDNY L



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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9NUG4-1-unknown MEYEVK... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9NUG4-1-unknown MEYEVK... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt69755
    Q9NUG4-1-unknown MEYEVK... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt69756

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...EDNYL 571 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)