TopFIND 4.0

Q9NUN7: Alkaline ceramidase 3

General Information

Protein names
- Alkaline ceramidase 3
- AlkCDase 3
- Alkaline CDase 3
- 3.5.1.- {ECO:0000269|PubMed:11356846, ECO:0000269|PubMed:20068046, ECO:0000269|PubMed:20207939}
- 3.5.1.23 {ECO:0000269|PubMed:20068046, ECO:0000269|PubMed:20207939, ECO:0000269|PubMed:26792856, ECO:0000269|PubMed:30575723}
- Alkaline dihydroceramidase SB89
- Alkaline phytoceramidase
- aPHC
Gene names ACER3
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q9NUN7

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAPAADREGY WGPTTSTLDW CEENYSVTWY IAEFWNTVSN LIMIIPPMFG AVQSVRDGLE 
        70         80         90        100        110        120 
KRYIASYLAL TVVGMGSWCF HMTLKYEMQL LDELPMIYSC CIFVYCMFEC FKIKNSVNYH 
       130        140        150        160        170        180 
LLFTLVLFSL IVTTVYLKVK EPIFHQVMYG MLVFTLVLRS IYIVTWVYPW LRGLGYTSLG 
       190        200        210        220        230        240 
IFLLGFLFWN IDNIFCESLR NFRKKVPPII GITTQFHAWW HILTGLGSYL HILFSLYTRT 
       250        260    
LYLRYRPKVK FLFGIWPVIL FEPLRKH

Isoforms

- Isoform 2 of Alkaline ceramidase 3

Sequence View

        10         20         30         40         50         60 
MAPAADREGY WGPTTSTLDW CEENYSVTWY IAEFWNTVSN LIMIIPPMFG AVQSVRDGLE 
        70         80         90        100        110        120 
KRYIASYLAL TVVGMGSWCF HMTLKYEMQL LDELPMIYSC CIFVYCMFEC FKIKNSVNYH 
       130        140        150        160        170        180 
LLFTLVLFSL IVTTVYLKVK EPIFHQVMYG MLVFTLVLRS IYIVTWVYPW LRGLGYTSLG 
       190        200        210        220        230        240 
IFLLGFLFWN IDNIFCESLR NFRKKVPPII GITTQFHAWW HILTGLGSYL HILFSLYTRT 
       250        260    
LYLRYRPKVK FLFGIWPVIL FEPLRKH



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9NUN7-1-unknown MAPAAD... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...PLRKH 267 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...PLRKH 267 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt61754

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)