TopFIND 4.0

Q9NUV7: Serine palmitoyltransferase 3 {ECO:0000305}

General Information

Protein names
- Serine palmitoyltransferase 3 {ECO:0000305}
- 2.3.1.50 {ECO:0000269|PubMed:19416851, ECO:0000269|PubMed:19648650}
- Long chain base biosynthesis protein 2b
- LCB2b
- Long chain base biosynthesis protein 3
- LCB 3
- Serine-palmitoyl-CoA transferase 3
- SPT 3
Gene names SPTLC3
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q9NUV7

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MANPGGGAVC NGKLHNHKKQ SNGSQSRNCT KNGIVKEAQQ NGKPHFYDKL IVESFEEAPL 
        70         80         90        100        110        120 
HVMVFTYMGY GIGTLFGYLR DFLRNWGIEK CNAAVERKEQ KDFVPLYQDF ENFYTRNLYM 
       130        140        150        160        170        180 
RIRDNWNRPI CSAPGPLFDL MERVSDDYNW TFRFTGRVIK DVINMGSYNF LGLAAKYDES 
       190        200        210        220        230        240 
MRTIKDVLEV YGTGVASTRH EMGTLDKHKE LEDLVAKFLN VEAAMVFGMG FATNSMNIPA 
       250        260        270        280        290        300 
LVGKGCLILS DELNHTSLVL GARLSGATIR IFKHNNTQSL EKLLRDAVIY GQPRTRRAWK 
       310        320        330        340        350        360 
KILILVEGVY SMEGSIVHLP QIIALKKKYK AYLYIDEAHS IGAVGPTGRG VTEFFGLDPH 
       370        380        390        400        410        420 
EVDVLMGTFT KSFGASGGYI AGRKDLVDYL RVHSHSAVYA SSMSPPIAEQ IIRSLKLIMG 
       430        440        450        460        470        480 
LDGTTQGLQR VQQLAKNTRY FRQRLQEMGF IIYGNENASV VPLLLYMPGK VAAFARHMLE 
       490        500        510        520        530        540 
KKIGVVVVGF PATPLAEARA RFCVSAAHTR EMLDTVLEAL DEMGDLLQLK YSRHKKSARP 
       550    
ELYDETSFEL ED

Isoforms

- Isoform 2 of Serine palmitoyltransferase 3

Sequence View

        10         20         30         40         50         60 
MANPGGGAVC NGKLHNHKKQ SNGSQSRNCT KNGIVKEAQQ NGKPHFYDKL IVESFEEAPL 
        70         80         90        100        110        120 
HVMVFTYMGY GIGTLFGYLR DFLRNWGIEK CNAAVERKEQ KDFVPLYQDF ENFYTRNLYM 
       130        140        150        160        170        180 
RIRDNWNRPI CSAPGPLFDL MERVSDDYNW TFRFTGRVIK DVINMGSYNF LGLAAKYDES 
       190        200        210        220        230        240 
MRTIKDVLEV YGTGVASTRH EMGTLDKHKE LEDLVAKFLN VEAAMVFGMG FATNSMNIPA 
       250        260        270        280        290        300 
LVGKGCLILS DELNHTSLVL GARLSGATIR IFKHNNTQSL EKLLRDAVIY GQPRTRRAWK 
       310        320        330        340        350        360 
KILILVEGVY SMEGSIVHLP QIIALKKKYK AYLYIDEAHS IGAVGPTGRG VTEFFGLDPH 
       370        380        390        400        410        420 
EVDVLMGTFT KSFGASGGYI AGRKDLVDYL RVHSHSAVYA SSMSPPIAEQ IIRSLKLIMG 
       430        440        450        460        470        480 
LDGTTQGLQR VQQLAKNTRY FRQRLQEMGF IIYGNENASV VPLLLYMPGK VAAFARHMLE 
       490        500        510        520        530        540 
KKIGVVVVGF PATPLAEARA RFCVSAAHTR EMLDTVLEAL DEMGDLLQLK YSRHKKSARP 
       550    
ELYDETSFEL ED



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9NUV7-1-unknown MANPGG... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9NUV7-1-unknown MANPGG... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt90569

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...FELED 552 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)