TopFIND 4.0

Q9NV23: S-acyl fatty acid synthase thioesterase, medium chain

General Information

Protein names
- S-acyl fatty acid synthase thioesterase, medium chain
- 3.1.2.14 {ECO:0000269|PubMed:26663084}
- Augmented in rheumatoid arthritis 1
- AURA1
- Oleoyl-ACP hydrolase
- Thioesterase 2 {ECO:0000303|PubMed:26663084}
- TE2 {ECO:0000303|PubMed:26663084}
- Thioesterase II
- Thioesterase domain-containing protein 1
Gene names OLAH
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q9NV23

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MERGDQPKRT RNENIFNCLY KNPEATFKLI CFPWMGGGST HFAKWGQDTH DLLEVHSLRL 
        70         80         90        100        110        120 
PGRESRVEEP LENDISQLVD EVVCALQPVI QDKPFAFFGH SMGSYIAFRT ALGLKENNQP 
       130        140        150        160        170        180 
EPLHLFLSSA TPVHSKAWHR IPKDDELSEE QISHYLMEFG GTPKHFAEAK EFVKQCSPII 
       190        200        210        220        230        240 
RADLNIVRSC TSNVPSKAVL SCDLTCFVGS EDIAKDMEAW KDVTSGNAKI YQLPGGHFYL 
       250        260    
LDPANEKLIK NYIIKCLEVS SISNF

Isoforms

- Isoform 2 of S-acyl fatty acid synthase thioesterase, medium chain

Sequence View

        10         20         30         40         50         60 
MERGDQPKRT RNENIFNCLY KNPEATFKLI CFPWMGGGST HFAKWGQDTH DLLEVHSLRL 
        70         80         90        100        110        120 
PGRESRVEEP LENDISQLVD EVVCALQPVI QDKPFAFFGH SMGSYIAFRT ALGLKENNQP 
       130        140        150        160        170        180 
EPLHLFLSSA TPVHSKAWHR IPKDDELSEE QISHYLMEFG GTPKHFAEAK EFVKQCSPII 
       190        200        210        220        230        240 
RADLNIVRSC TSNVPSKAVL SCDLTCFVGS EDIAKDMEAW KDVTSGNAKI YQLPGGHFYL 
       250        260    
LDPANEKLIK NYIIKCLEVS SISNF



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9NV23-1-Acetylation MERGDQ... 1 acetylation- inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9NV23-1-Acetylation MERGDQ... 1 acetylation- inferred from isoform by sequence similarity unknown TopFIND inferred from TNt96531
    Q9NV23-1-unknown MERGDQ... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt88893

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...SISNF 265 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...SISNF 265 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt84511

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)