Q9NV58: E3 ubiquitin-protein ligase RNF19A

General Information

Protein names	- E3 ubiquitin-protein ligase RNF19A - 2.3.2.31 {ECO:0000250\|UniProtKB:O60260} - Double ring-finger protein - Dorfin - RING finger protein 19A - p38
Gene names	RNF19A
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9NV58

2 N-termini

5 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of E3 ubiquitin-protein ligase RNF19A - Isoform 3 of E3 ubiquitin-protein ligase RNF19A

Sequence View

        10         20         30         40         50         60
MQEQEIGFIS KYNEGLCVNT DPVSILTSIL DMSLHRQMGS DRDLQSSASS VSLPSVKKAP
        70         80         90        100        110        120
KKRRISIGSL FRRKKDNKRK SRELNGGVDG IASIESIHSE MCTDKNSIFS TNTSSDNGLT
       130        140        150        160        170        180
SISKQIGDFI ECPLCLLRHS KDRFPDIMTC HHRSCVDCLR QYLRIEISES RVNISCPECT
       190        200        210        220        230        240
ERFNPHDIRL ILSDDVLMEK YEEFMLRRWL VADPDCRWCP APDCGYAVIA FGCASCPKLT
       250        260        270        280        290        300
CGREGCGTEF CYHCKQIWHP NQTCDAARQE RAQSLRLRTI RSSSISYSQE SGAAADDIKP
       310        320        330        340        350        360
CPRCAAYIIK MNDGSCNHMT CAVCGCEFCW LCMKEISDLH YLSPSGCTFW GKKPWSRKKK
       370        380        390        400        410        420
ILWQLGTLVG APVGIALIAG IAIPAMIIGI PVYVGRKIHN RYEGKDVSKH KRNLAIAGGV
       430        440        450        460        470        480
TLSVIVSPVV AAVTVGIGVP IMLAYVYGVV PISLCRSGGC GVSAGNGKGV RIEFDDENDI
       490        500        510        520        530        540
NVGGTNTAVD TTSVAEARHN PSIGEGSVGG LTGSLSASGS HMDRIGAIRD NLSETASTMA
       550        560        570        580        590        600
LAGASITGSL SGSAMVNCFN RLEVQADVQK ERYSLSGESG TVSLGTVSDN ASTKAMAGSI
       610        620        630        640        650        660
LNSYIPLDKE GNSMEVQVDI ESKPSKFRHN SGSSSVDDGS ATRSHAGGSS SGLPEGKSSA
       670        680        690        700        710        720
TKWSKEATAG KKSKSGKLRK KGNMKINETR EDMDAQLLEQ QSTNSSEFEA PSLSDSMPSV
       730        740        750        760        770        780
ADSHSSHFSE FSCSDLESMK TSCSHGSSDY HTRFATVNIL PEVENDRLEN SPHQCSISVV
       790        800        810        820        830
TQTASCSEVS QLNHIAEEHG NNGIKPNVDL YFGDALKETN NNHSHQTMEL KVAIQTEI         10         20         30         40         50         60
MQEQEIGFIS KYNEGLCVNT DPVSILTSIL DMSLHRQMGS DRDLQSSASS VSLPSVKKAP
        70         80         90        100        110        120
KKRRISIGSL FRRKKDNKRK SRELNGGVDG IASIESIHSE MCTDKNSIFS TNTSSDNGLT
       130        140        150        160        170        180
SISKQIGDFI ECPLCLLRHS KDRFPDIMTC HHRSCVDCLR QYLRIEISES RVNISCPECT
       190        200        210        220        230        240
ERFNPHDIRL ILSDDVLMEK YEEFMLRRWL VADPDCRWCP APDCGYAVIA FGCASCPKLT
       250        260        270        280        290        300
CGREGCGTEF CYHCKQIWHP NQTCDAARQE RAQSLRLRTI RSSSISYSQE SGAAADDIKP
       310        320        330        340        350        360
CPRCAAYIIK MNDGSCNHMT CAVCGCEFCW LCMKEISDLH YLSPSGCTFW GKKPWSRKKK
       370        380        390        400        410        420
ILWQLGTLVG APVGIALIAG IAIPAMIIGI PVYVGRKIHN RYEGKDVSKH KRNLAIAGGV
       430        440        450        460        470        480
TLSVIVSPVV AAVTVGIGVP IMLAYVYGVV PISLCRSGGC GVSAGNGKGV RIEFDDENDI
       490        500        510        520        530        540
NVGGTNTAVD TTSVAEARHN PSIGEGSVGG LTGSLSASGS HMDRIGAIRD NLSETASTMA
       550        560        570        580        590        600
LAGASITGSL SGSAMVNCFN RLEVQADVQK ERYSLSGESG TVSLGTVSDN ASTKAMAGSI
       610        620        630        640        650        660
LNSYIPLDKE GNSMEVQVDI ESKPSKFRHN SGSSSVDDGS ATRSHAGGSS SGLPEGKSSA
       670        680        690        700        710        720
TKWSKEATAG KKSKSGKLRK KGNMKINETR EDMDAQLLEQ QSTNSSEFEA PSLSDSMPSV
       730        740        750        760        770        780
ADSHSSHFSE FSCSDLESMK TSCSHGSSDY HTRFATVNIL PEVENDRLEN SPHQCSISVV
       790        800        810        820        830
TQTASCSEVS QLNHIAEEHG NNGIKPNVDL YFGDALKETN NNHSHQTMEL KVAIQTEI

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 5 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q9NV58-1-unknown	MQEQEI...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9NV58-1-unknown	MQEQEI...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt87934
Q9NV58-32-unknown	MSLHRQ...	32	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt87935
Q9NV58-32-unknown	MSLHRQ...	32	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000429161
Q9NV58-32-unknown	MSLHRQ...	32	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt103117

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...NGGVDG	89	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000429161
...NGGVDG	89	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000397305
...NGGVDG	89	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154266
...NGGVDG	89	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154267
...FSTNTS	113	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000429841
...FSTNTS	113	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154502
...FSTNTS	113	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154503
...HRSCVD	156	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000429549
...HRSCVD	156	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155035
...HRSCVD	156	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155036
...QYLRIE	165	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000431077
...QYLRIE	165	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155187
...QYLRIE	165	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt155188
...IQTEI	838	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...IQTEI	838	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt83553

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)