TopFIND 4.0

Q9NVH0: Exonuclease 3'-5' domain-containing protein 2 {ECO:0000312|HGNC:HGNC:20217}

General Information

Protein names
- Exonuclease 3'-5' domain-containing protein 2 {ECO:0000312|HGNC:HGNC:20217}
- 3.1.11.1 {ECO:0000269|PubMed:26807646}
- Exonuclease 3'-5' domain-like-containing protein 2
Gene names EXD2
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q9NVH0

2

N-termini

3

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSRQNLVALT VTTLLGVAVG GFVLWKGIQR RRRSKTSPVT QQPQQKVLGS RELPPPEDDQ 
        70         80         90        100        110        120 
LHSSAPRSSW KERILKAKVV TVSQEAEWDQ IEPLLRSELE DFPVLGIDCE WVNLEGKASP 
       130        140        150        160        170        180 
LSLLQMASPS GLCVLVRLPK LICGGKTLPR TLLDILADGT ILKVGVGCSE DASKLLQDYG 
       190        200        210        220        230        240 
LVVRGCLDLR YLAMRQRNNL LCNGLSLKSL AETVLNFPLD KSLLLRCSNW DAETLTEDQV 
       250        260        270        280        290        300 
IYAARDAQIS VALFLHLLGY PFSRNSPGEK NDDHSSWRKV LEKCQGVVDI PFRSKGMSRL 
       310        320        330        340        350        360 
GEEVNGEATE SQQKPRNKKS KMDGMVPGNH QGRDPRKHKR KPLGVGYSAR KSPLYDNCFL 
       370        380        390        400        410        420 
HAPDGQPLCT CDRRKAQWYL DKGIGELVSE EPFVVKLRFE PAGRPESPGD YYLMVKENLC 
       430        440        450        460        470        480 
VVCGKRDSYI RKNVIPHEYR KHFPIEMKDH NSHDVLLLCT SCHAISNYYD NHLKQQLAKE 
       490        500        510        520        530        540 
FQAPIGSEEG LRLLEDPERR QVRSGARALL NAESLPTQRK EELLQALREF YNTDVVTEEM 
       550        560        570        580        590        600 
LQEAASLETR ISNENYVPHG LKVVQCHSQG GLRSLMQLES RWRQHFLDSM QPKHLPQQWS 
       610        620    
VDHNHQKLLR KFGEDLPIQL S

Isoforms

- Isoform 2 of Exonuclease 3'-5' domain-containing protein 2

Sequence View

        10         20         30         40         50         60 
MSRQNLVALT VTTLLGVAVG GFVLWKGIQR RRRSKTSPVT QQPQQKVLGS RELPPPEDDQ 
        70         80         90        100        110        120 
LHSSAPRSSW KERILKAKVV TVSQEAEWDQ IEPLLRSELE DFPVLGIDCE WVNLEGKASP 
       130        140        150        160        170        180 
LSLLQMASPS GLCVLVRLPK LICGGKTLPR TLLDILADGT ILKVGVGCSE DASKLLQDYG 
       190        200        210        220        230        240 
LVVRGCLDLR YLAMRQRNNL LCNGLSLKSL AETVLNFPLD KSLLLRCSNW DAETLTEDQV 
       250        260        270        280        290        300 
IYAARDAQIS VALFLHLLGY PFSRNSPGEK NDDHSSWRKV LEKCQGVVDI PFRSKGMSRL 
       310        320        330        340        350        360 
GEEVNGEATE SQQKPRNKKS KMDGMVPGNH QGRDPRKHKR KPLGVGYSAR KSPLYDNCFL 
       370        380        390        400        410        420 
HAPDGQPLCT CDRRKAQWYL DKGIGELVSE EPFVVKLRFE PAGRPESPGD YYLMVKENLC 
       430        440        450        460        470        480 
VVCGKRDSYI RKNVIPHEYR KHFPIEMKDH NSHDVLLLCT SCHAISNYYD NHLKQQLAKE 
       490        500        510        520        530        540 
FQAPIGSEEG LRLLEDPERR QVRSGARALL NAESLPTQRK EELLQALREF YNTDVVTEEM 
       550        560        570        580        590        600 
LQEAASLETR ISNENYVPHG LKVVQCHSQG GLRSLMQLES RWRQHFLDSM QPKHLPQQWS 
       610        620    
VDHNHQKLLR KFGEDLPIQL S



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(REFRESH)

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Protein Neighborhood

Domains & Features

2 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9NVH0-1-unknown MSRQNL... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9NVH0-126-unknown MASPSG... 126 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt74303

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)