Q9NWM0: Spermine oxidase

General Information

Protein names	- Spermine oxidase - 1.5.3.16 {ECO:0000269\|PubMed:11454677, ECO:0000269\|PubMed:12398765} - Polyamine oxidase 1 - PAO-1 - PAOh1
Gene names	SMOX
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9NWM0

3 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Spermine oxidase - Isoform 3 of Spermine oxidase - Isoform 4 of Spermine oxidase - Isoform 5 of Spermine oxidase - Isoform 6 of Spermine oxidase

Sequence View

        10         20         30         40         50         60
MQSCESSGDS ADDPLSRGLR RRGQPRVVVI GAGLAGLAAA KALLEQGFTD VTVLEASSHI
        70         80         90        100        110        120
GGRVQSVKLG HATFELGATW IHGSHGNPIY HLAEANGLLE ETTDGERSVG RISLYSKNGV
       130        140        150        160        170        180
ACYLTNHGRR IPKDVVEEFS DLYNEVYNLT QEFFRHDKPV NAESQNSVGV FTREEVRNRI
       190        200        210        220        230        240
RNDPDDPEAT KRLKLAMIQQ YLKVESCESS SHSMDEVSLS AFGEWTEIPG AHHIIPSGFM
       250        260        270        280        290        300
RVVELLAEGI PAHVIQLGKP VRCIHWDQAS ARPRGPEIEP RGEGDHNHDT GEGGQGGEEP
       310        320        330        340        350        360
RGGRWDEDEQ WSVVVECEDC ELIPADHVIV TVSLGVLKRQ YTSFFRPGLP TEKVAAIHRL
       370        380        390        400        410        420
GIGTTDKIFL EFEEPFWGPE CNSLQFVWED EAESHTLTYP PELWYRKICG FDVLYPPERY
       430        440        450        460        470        480
GHVLSGWICG EEALVMEKCD DEAVAEICTE MLRQFTGNPN IPKPRRILRS AWGSNPYFRG
       490        500        510        520        530        540
SYSYTQVGSS GADVEKLAKP LPYTESSKTA PMQVLFSGEA THRKYYSTTH GALLSGQREA
       550
ARLIEMYRDL FQQGT         10         20         30         40         50         60
MQSCESSGDS ADDPLSRGLR RRGQPRVVVI GAGLAGLAAA KALLEQGFTD VTVLEASSHI
        70         80         90        100        110        120
GGRVQSVKLG HATFELGATW IHGSHGNPIY HLAEANGLLE ETTDGERSVG RISLYSKNGV
       130        140        150        160        170        180
ACYLTNHGRR IPKDVVEEFS DLYNEVYNLT QEFFRHDKPV NAESQNSVGV FTREEVRNRI
       190        200        210        220        230        240
RNDPDDPEAT KRLKLAMIQQ YLKVESCESS SHSMDEVSLS AFGEWTEIPG AHHIIPSGFM
       250        260        270        280        290        300
RVVELLAEGI PAHVIQLGKP VRCIHWDQAS ARPRGPEIEP RGEGDHNHDT GEGGQGGEEP
       310        320        330        340        350        360
RGGRWDEDEQ WSVVVECEDC ELIPADHVIV TVSLGVLKRQ YTSFFRPGLP TEKVAAIHRL
       370        380        390        400        410        420
GIGTTDKIFL EFEEPFWGPE CNSLQFVWED EAESHTLTYP PELWYRKICG FDVLYPPERY
       430        440        450        460        470        480
GHVLSGWICG EEALVMEKCD DEAVAEICTE MLRQFTGNPN IPKPRRILRS AWGSNPYFRG
       490        500        510        520        530        540
SYSYTQVGSS GADVEKLAKP LPYTESSKTA PMQVLFSGEA THRKYYSTTH GALLSGQREA
       550
ARLIEMYRDL FQQGT         10         20         30         40         50         60
MQSCESSGDS ADDPLSRGLR RRGQPRVVVI GAGLAGLAAA KALLEQGFTD VTVLEASSHI
        70         80         90        100        110        120
GGRVQSVKLG HATFELGATW IHGSHGNPIY HLAEANGLLE ETTDGERSVG RISLYSKNGV
       130        140        150        160        170        180
ACYLTNHGRR IPKDVVEEFS DLYNEVYNLT QEFFRHDKPV NAESQNSVGV FTREEVRNRI
       190        200        210        220        230        240
RNDPDDPEAT KRLKLAMIQQ YLKVESCESS SHSMDEVSLS AFGEWTEIPG AHHIIPSGFM
       250        260        270        280        290        300
RVVELLAEGI PAHVIQLGKP VRCIHWDQAS ARPRGPEIEP RGEGDHNHDT GEGGQGGEEP
       310        320        330        340        350        360
RGGRWDEDEQ WSVVVECEDC ELIPADHVIV TVSLGVLKRQ YTSFFRPGLP TEKVAAIHRL
       370        380        390        400        410        420
GIGTTDKIFL EFEEPFWGPE CNSLQFVWED EAESHTLTYP PELWYRKICG FDVLYPPERY
       430        440        450        460        470        480
GHVLSGWICG EEALVMEKCD DEAVAEICTE MLRQFTGNPN IPKPRRILRS AWGSNPYFRG
       490        500        510        520        530        540
SYSYTQVGSS GADVEKLAKP LPYTESSKTA PMQVLFSGEA THRKYYSTTH GALLSGQREA
       550
ARLIEMYRDL FQQGT         10         20         30         40         50         60
MQSCESSGDS ADDPLSRGLR RRGQPRVVVI GAGLAGLAAA KALLEQGFTD VTVLEASSHI
        70         80         90        100        110        120
GGRVQSVKLG HATFELGATW IHGSHGNPIY HLAEANGLLE ETTDGERSVG RISLYSKNGV
       130        140        150        160        170        180
ACYLTNHGRR IPKDVVEEFS DLYNEVYNLT QEFFRHDKPV NAESQNSVGV FTREEVRNRI
       190        200        210        220        230        240
RNDPDDPEAT KRLKLAMIQQ YLKVESCESS SHSMDEVSLS AFGEWTEIPG AHHIIPSGFM
       250        260        270        280        290        300
RVVELLAEGI PAHVIQLGKP VRCIHWDQAS ARPRGPEIEP RGEGDHNHDT GEGGQGGEEP
       310        320        330        340        350        360
RGGRWDEDEQ WSVVVECEDC ELIPADHVIV TVSLGVLKRQ YTSFFRPGLP TEKVAAIHRL
       370        380        390        400        410        420
GIGTTDKIFL EFEEPFWGPE CNSLQFVWED EAESHTLTYP PELWYRKICG FDVLYPPERY
       430        440        450        460        470        480
GHVLSGWICG EEALVMEKCD DEAVAEICTE MLRQFTGNPN IPKPRRILRS AWGSNPYFRG
       490        500        510        520        530        540
SYSYTQVGSS GADVEKLAKP LPYTESSKTA PMQVLFSGEA THRKYYSTTH GALLSGQREA
       550
ARLIEMYRDL FQQGT         10         20         30         40         50         60
MQSCESSGDS ADDPLSRGLR RRGQPRVVVI GAGLAGLAAA KALLEQGFTD VTVLEASSHI
        70         80         90        100        110        120
GGRVQSVKLG HATFELGATW IHGSHGNPIY HLAEANGLLE ETTDGERSVG RISLYSKNGV
       130        140        150        160        170        180
ACYLTNHGRR IPKDVVEEFS DLYNEVYNLT QEFFRHDKPV NAESQNSVGV FTREEVRNRI
       190        200        210        220        230        240
RNDPDDPEAT KRLKLAMIQQ YLKVESCESS SHSMDEVSLS AFGEWTEIPG AHHIIPSGFM
       250        260        270        280        290        300
RVVELLAEGI PAHVIQLGKP VRCIHWDQAS ARPRGPEIEP RGEGDHNHDT GEGGQGGEEP
       310        320        330        340        350        360
RGGRWDEDEQ WSVVVECEDC ELIPADHVIV TVSLGVLKRQ YTSFFRPGLP TEKVAAIHRL
       370        380        390        400        410        420
GIGTTDKIFL EFEEPFWGPE CNSLQFVWED EAESHTLTYP PELWYRKICG FDVLYPPERY
       430        440        450        460        470        480
GHVLSGWICG EEALVMEKCD DEAVAEICTE MLRQFTGNPN IPKPRRILRS AWGSNPYFRG
       490        500        510        520        530        540
SYSYTQVGSS GADVEKLAKP LPYTESSKTA PMQVLFSGEA THRKYYSTTH GALLSGQREA
       550
ARLIEMYRDL FQQGT

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9NWM0-1-unknown	MQSCES...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9NWM0-1-unknown	MQSCES...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt90064
Q9NWM0-1-unknown	MQSCES...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt90065
Q9NWM0-1-unknown	MQSCES...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt90066
Q9NWM0-1-unknown	MQSCES...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt90068
Q9NWM0-1-acetylation	MQSCES...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q9NWM0-1-acetylation	MQSCES...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt179034
Q9NWM0-1-acetylation	MQSCES...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt179035
Q9NWM0-1-acetylation	MQSCES...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt179036
Q9NWM0-1-acetylation	MQSCES...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt179037
Q9NWM0-197-unknown	MIQQYL...	197		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt90067
Q9NWM0-197-unknown	MIQQYL...	197		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt107719
Q9NWM0-197-unknown	MIQQYL...	197		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt107720
Q9NWM0-197-unknown	MIQQYL...	197		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt107721

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...FQQGT	555	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...FQQGT	555	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt85683
...FQQGT	555	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt85685
...FQQGT	555	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt85682
...FQQGT	555	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt85684
...FQQGT	555	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt85686

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)