Q9NWS1: PCNA-interacting partner

General Information

Protein names	- PCNA-interacting partner - PARI - PARP-1 binding protein - PARP1-binding protein - PARPBP
Gene names	PARPBP
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9NWS1

4 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of PCNA-interacting partner - Isoform 3 of PCNA-interacting partner - Isoform 4 of PCNA-interacting partner - Isoform 5 of PCNA-interacting partner - Isoform 6 of PCNA-interacting partner - Isoform 7 of PCNA-interacting partner

Sequence View

        10         20         30         40         50         60
MAVFNQKSVS DMIKEFRKNW RALCNSERTT LCGADSMLLA LQLSMAENNK QHSGEFTVSL
        70         80         90        100        110        120
SDVLLTWKYL LHEKLNLPVE NMDVTDHYED VRKIYDDFLK NSNMLDLIDV YQKCRALTSN
       130        140        150        160        170        180
CENYNTVSPS QLLDFLSGKQ YAVGDETDLS IPTSPTSKYN RDNEKVQLLA RKIIFSYLNL
       190        200        210        220        230        240
LVNSKNDLAV AYILNIPDRG LGREAFTDLK HAAREKQMSI FLVATSFIRT IELGGKGYAP
       250        260        270        280        290        300
PPSDPLRTHV KGLSNFINFI DKLDEILGEI PNPSIAGGQI LSVIKMQLIK GQNSRDPFCK
       310        320        330        340        350        360
AIEEVAQDLD LRIKNIINSQ EGVVALSTTD ISPARPKSHA INHGTAYCGR DTVKALLVLL
       370        380        390        400        410        420
DEEAANAPTK NKAELLYDEE NTIHHHGTSI LTLFRSPTQV NNSIKPLRER ICVSMQEKKI
       430        440        450        460        470        480
KMKQTLIRSQ FACTYKDDYM ISKDNWNNVN LASKPLCVLY MENDLSEGVN PSVGRSTIGT
       490        500        510        520        530        540
SFGNVHLDRS KNEKVSRKST SQTGNKSSKR KQVDLDGENI LCDNRNEPPQ HKNAKIPKKS
       550        560        570
NDSQNRLYGK LAKVAKSNKC TAKDKLISGQ AKLTQFFRL         10         20         30         40         50         60
MAVFNQKSVS DMIKEFRKNW RALCNSERTT LCGADSMLLA LQLSMAENNK QHSGEFTVSL
        70         80         90        100        110        120
SDVLLTWKYL LHEKLNLPVE NMDVTDHYED VRKIYDDFLK NSNMLDLIDV YQKCRALTSN
       130        140        150        160        170        180
CENYNTVSPS QLLDFLSGKQ YAVGDETDLS IPTSPTSKYN RDNEKVQLLA RKIIFSYLNL
       190        200        210        220        230        240
LVNSKNDLAV AYILNIPDRG LGREAFTDLK HAAREKQMSI FLVATSFIRT IELGGKGYAP
       250        260        270        280        290        300
PPSDPLRTHV KGLSNFINFI DKLDEILGEI PNPSIAGGQI LSVIKMQLIK GQNSRDPFCK
       310        320        330        340        350        360
AIEEVAQDLD LRIKNIINSQ EGVVALSTTD ISPARPKSHA INHGTAYCGR DTVKALLVLL
       370        380        390        400        410        420
DEEAANAPTK NKAELLYDEE NTIHHHGTSI LTLFRSPTQV NNSIKPLRER ICVSMQEKKI
       430        440        450        460        470        480
KMKQTLIRSQ FACTYKDDYM ISKDNWNNVN LASKPLCVLY MENDLSEGVN PSVGRSTIGT
       490        500        510        520        530        540
SFGNVHLDRS KNEKVSRKST SQTGNKSSKR KQVDLDGENI LCDNRNEPPQ HKNAKIPKKS
       550        560        570
NDSQNRLYGK LAKVAKSNKC TAKDKLISGQ AKLTQFFRL         10         20         30         40         50         60
MAVFNQKSVS DMIKEFRKNW RALCNSERTT LCGADSMLLA LQLSMAENNK QHSGEFTVSL
        70         80         90        100        110        120
SDVLLTWKYL LHEKLNLPVE NMDVTDHYED VRKIYDDFLK NSNMLDLIDV YQKCRALTSN
       130        140        150        160        170        180
CENYNTVSPS QLLDFLSGKQ YAVGDETDLS IPTSPTSKYN RDNEKVQLLA RKIIFSYLNL
       190        200        210        220        230        240
LVNSKNDLAV AYILNIPDRG LGREAFTDLK HAAREKQMSI FLVATSFIRT IELGGKGYAP
       250        260        270        280        290        300
PPSDPLRTHV KGLSNFINFI DKLDEILGEI PNPSIAGGQI LSVIKMQLIK GQNSRDPFCK
       310        320        330        340        350        360
AIEEVAQDLD LRIKNIINSQ EGVVALSTTD ISPARPKSHA INHGTAYCGR DTVKALLVLL
       370        380        390        400        410        420
DEEAANAPTK NKAELLYDEE NTIHHHGTSI LTLFRSPTQV NNSIKPLRER ICVSMQEKKI
       430        440        450        460        470        480
KMKQTLIRSQ FACTYKDDYM ISKDNWNNVN LASKPLCVLY MENDLSEGVN PSVGRSTIGT
       490        500        510        520        530        540
SFGNVHLDRS KNEKVSRKST SQTGNKSSKR KQVDLDGENI LCDNRNEPPQ HKNAKIPKKS
       550        560        570
NDSQNRLYGK LAKVAKSNKC TAKDKLISGQ AKLTQFFRL         10         20         30         40         50         60
MAVFNQKSVS DMIKEFRKNW RALCNSERTT LCGADSMLLA LQLSMAENNK QHSGEFTVSL
        70         80         90        100        110        120
SDVLLTWKYL LHEKLNLPVE NMDVTDHYED VRKIYDDFLK NSNMLDLIDV YQKCRALTSN
       130        140        150        160        170        180
CENYNTVSPS QLLDFLSGKQ YAVGDETDLS IPTSPTSKYN RDNEKVQLLA RKIIFSYLNL
       190        200        210        220        230        240
LVNSKNDLAV AYILNIPDRG LGREAFTDLK HAAREKQMSI FLVATSFIRT IELGGKGYAP
       250        260        270        280        290        300
PPSDPLRTHV KGLSNFINFI DKLDEILGEI PNPSIAGGQI LSVIKMQLIK GQNSRDPFCK
       310        320        330        340        350        360
AIEEVAQDLD LRIKNIINSQ EGVVALSTTD ISPARPKSHA INHGTAYCGR DTVKALLVLL
       370        380        390        400        410        420
DEEAANAPTK NKAELLYDEE NTIHHHGTSI LTLFRSPTQV NNSIKPLRER ICVSMQEKKI
       430        440        450        460        470        480
KMKQTLIRSQ FACTYKDDYM ISKDNWNNVN LASKPLCVLY MENDLSEGVN PSVGRSTIGT
       490        500        510        520        530        540
SFGNVHLDRS KNEKVSRKST SQTGNKSSKR KQVDLDGENI LCDNRNEPPQ HKNAKIPKKS
       550        560        570
NDSQNRLYGK LAKVAKSNKC TAKDKLISGQ AKLTQFFRL         10         20         30         40         50         60
MAVFNQKSVS DMIKEFRKNW RALCNSERTT LCGADSMLLA LQLSMAENNK QHSGEFTVSL
        70         80         90        100        110        120
SDVLLTWKYL LHEKLNLPVE NMDVTDHYED VRKIYDDFLK NSNMLDLIDV YQKCRALTSN
       130        140        150        160        170        180
CENYNTVSPS QLLDFLSGKQ YAVGDETDLS IPTSPTSKYN RDNEKVQLLA RKIIFSYLNL
       190        200        210        220        230        240
LVNSKNDLAV AYILNIPDRG LGREAFTDLK HAAREKQMSI FLVATSFIRT IELGGKGYAP
       250        260        270        280        290        300
PPSDPLRTHV KGLSNFINFI DKLDEILGEI PNPSIAGGQI LSVIKMQLIK GQNSRDPFCK
       310        320        330        340        350        360
AIEEVAQDLD LRIKNIINSQ EGVVALSTTD ISPARPKSHA INHGTAYCGR DTVKALLVLL
       370        380        390        400        410        420
DEEAANAPTK NKAELLYDEE NTIHHHGTSI LTLFRSPTQV NNSIKPLRER ICVSMQEKKI
       430        440        450        460        470        480
KMKQTLIRSQ FACTYKDDYM ISKDNWNNVN LASKPLCVLY MENDLSEGVN PSVGRSTIGT
       490        500        510        520        530        540
SFGNVHLDRS KNEKVSRKST SQTGNKSSKR KQVDLDGENI LCDNRNEPPQ HKNAKIPKKS
       550        560        570
NDSQNRLYGK LAKVAKSNKC TAKDKLISGQ AKLTQFFRL         10         20         30         40         50         60
MAVFNQKSVS DMIKEFRKNW RALCNSERTT LCGADSMLLA LQLSMAENNK QHSGEFTVSL
        70         80         90        100        110        120
SDVLLTWKYL LHEKLNLPVE NMDVTDHYED VRKIYDDFLK NSNMLDLIDV YQKCRALTSN
       130        140        150        160        170        180
CENYNTVSPS QLLDFLSGKQ YAVGDETDLS IPTSPTSKYN RDNEKVQLLA RKIIFSYLNL
       190        200        210        220        230        240
LVNSKNDLAV AYILNIPDRG LGREAFTDLK HAAREKQMSI FLVATSFIRT IELGGKGYAP
       250        260        270        280        290        300
PPSDPLRTHV KGLSNFINFI DKLDEILGEI PNPSIAGGQI LSVIKMQLIK GQNSRDPFCK
       310        320        330        340        350        360
AIEEVAQDLD LRIKNIINSQ EGVVALSTTD ISPARPKSHA INHGTAYCGR DTVKALLVLL
       370        380        390        400        410        420
DEEAANAPTK NKAELLYDEE NTIHHHGTSI LTLFRSPTQV NNSIKPLRER ICVSMQEKKI
       430        440        450        460        470        480
KMKQTLIRSQ FACTYKDDYM ISKDNWNNVN LASKPLCVLY MENDLSEGVN PSVGRSTIGT
       490        500        510        520        530        540
SFGNVHLDRS KNEKVSRKST SQTGNKSSKR KQVDLDGENI LCDNRNEPPQ HKNAKIPKKS
       550        560        570
NDSQNRLYGK LAKVAKSNKC TAKDKLISGQ AKLTQFFRL

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q9NWS1-1-unknown	MAVFNQ...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9NWS1-1-unknown	MAVFNQ...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt84313
Q9NWS1-1-unknown	MAVFNQ...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt84314
Q9NWS1-1-unknown	MAVFNQ...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt84316
Q9NWS1-1-unknown	MAVFNQ...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt84317
Q9NWS1-34-unknown	ADSMLL...	34	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000411313
Q9NWS1-34-unknown	ADSMLL...	34	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000393867
Q9NWS1-34-unknown	ADSMLL...	34	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt195748
Q9NWS1-34-unknown	ADSMLL...	34	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt195749
Q9NWS1-34-unknown	ADSMLL...	34	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt195750
Q9NWS1-34-unknown	ADSMLL...	34	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt195751
Q9NWS1-82-unknown	MDVTDH...	82	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt84312
Q9NWS1-82-unknown	MDVTDH...	82	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000376643
Q9NWS1-82-unknown	MDVTDH...	82	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000332915
Q9NWS1-82-unknown	MDVTDH...	82	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt100904
Q9NWS1-82-unknown	MDVTDH...	82	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt100905
Q9NWS1-82-unknown	MDVTDH...	82	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt100906
Q9NWS1-82-unknown	MDVTDH...	82	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt100907
Q9NWS1-286-unknown	MQLIKG...	286	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt84315
Q9NWS1-286-unknown	MQLIKG...	286	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt101062

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...QFFRL	579	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...QFFRL	579	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt79933
...QFFRL	579	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt79930

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)