Q9NX74: tRNA-dihydrouridine(20) synthase [NAD(P)+]-like

General Information

Protein names	- tRNA-dihydrouridine(20) synthase NAD(P)+]-like - 1.3.1.91 {ECO:0000269\|PubMed:15994936, ECO:0000269\|PubMed:26429968, ECO:0000269\|PubMed:30149704} - Dihydrouridine synthase 2 - Up-regulated in lung cancer protein 8 - URLC8 - tRNA-dihydrouridine synthase 2-like - hDUS2
Gene names	DUS2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9NX74

1 N-termini

11 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MILNSLSLCY HNKLILAPMV RVGTLPMRLL ALDYGADIVY CEELIDLKMI QCKRVVNEVL
        70         80         90        100        110        120
STVDFVAPDD RVVFRTCERE QNRVVFQMGT SDAERALAVA RLVENDVAGI DVNMGCPKQY
       130        140        150        160        170        180
STKGGMGAAL LSDPDKIEKI LSTLVKGTRR PVTCKIRILP SLEDTLSLVK RIERTGIAAI
       190        200        210        220        230        240
AVHGRKREER PQHPVSCEVI KAIADTLSIP VIANGGSHDH IQQYSDIEDF RQATAASSVM
       250        260        270        280        290        300
VARAAMWNPS IFLKEGLRPL EEVMQKYIRY AVQYDNHYTN TKYCLCQMLR EQLESPQGRL
       310        320        330        340        350        360
LHAAQSSREI CEAFGLGAFY EETTQELDAQ QARLSAKTSE QTGEPAEDTS GVIKMAVKFD
       370        380        390        400        410        420
RRAYPAQITP KMCLLEWCRR EKLAQPVYET VQRPLDRLFS SIVTVAEQKY QSTLWDKSKK
       430        440        450        460        470        480
LAEQAAAIVC LRSQGLPEGR LGEESPSLHK RKREAPDQDP GGPRAQELAQ PGDLCKKPFV
       490
ALGSGEESPL EGW

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

1 N-termini - 11 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9NX74-1-unknown	MILNSL...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...DIVYCE	41	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000456261
...LKMIQC	51	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000456677
...DDRVVF	73	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000458152
...CEREQN	81	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000454424
...VFQMGT	89	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000458906
...VENDVA	107	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000455977
...DVNMGC	115	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000454252
...YSTKGG	124	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000461244
...CKIRIL	158	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000461659
...ADTLSI	208	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000463498
...PLEGW	493	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)