TopFIND 4.0

Q9NXI6: E3 ubiquitin-protein ligase RNF186 {ECO:0000305}

General Information

Protein names
- E3 ubiquitin-protein ligase RNF186 {ECO:0000305}
- 2.3.2.27 {ECO:0000269|PubMed:23896122}
- RING finger protein 186 {ECO:0000312|HGNC:HGNC:25978}
Gene names RNF186
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q9NXI6

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MACTKTLQQS QPISAGATTT TTAVAPAGGH SGSTECDLEC LVCREPYSCP RLPKLLACQH 
        70         80         90        100        110        120 
AFCAICLKLL LCVQDNTWSI TCPLCRKVTA VPGGLICSLR DHEAVVGQLA QPCTEVSLCP 
       130        140        150        160        170        180 
QGLVDPADLA AGHPSLVGED GQDEVSANHV AARRLAAHLL LLALLIILIG PFIYPGVLRW 
       190        200        210        220    
VLTFIIALAL LMSTLFCCLP STRGSCWPSS RTLFCREQKH SHISSIA

Isoforms



Sequence View



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9NXI6-1-unknown MACTKT... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...ISSIA 227 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)