TopFIND 4.0

Q9NXS3: Kelch-like protein 28

General Information

Protein names
- Kelch-like protein 28
- BTB/POZ domain-containing protein 5
Gene names KLHL28
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q9NXS3

1

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MDHTSPTYML ANLTHLHSEQ LLQGLNLLRQ HHELCDIILR VGDVKIHAHK VVLASVSPYF 
        70         80         90        100        110        120 
KAMFTGNLSE KENSEVEFQC IDETALQAIV EYAYTGTVFI SQDTVESLLP AANLLQIKLV 
       130        140        150        160        170        180 
LKECCAFLES QLDPGNCIGI SRFAETYGCR DLYLAATKYI CQNFEAVCQT EEFFELTHAD 
       190        200        210        220        230        240 
LDEIVSNDCL NVATEETVFY ALESWIKYDV QERQKYLAQL LNSVRLPLLS VKFLTRLYEA 
       250        260        270        280        290        300 
NHLIRDDRTC KHLLNEALKY HFMPEHRLSH QTVLMTRPRC APKVLCAVGG KSGLFACLDS 
       310        320        330        340        350        360 
VEMYFPQNDS WIGLAPLNIP RYEFGICVLD QKVYVIGGIA TNVRPGVTIR KHENSVECWN 
       370        380        390        400        410        420 
PDTNTWTSLE RMNESRSTLG VVVLAGELYA LGGYDGQSYL QSVEKYIPKI RKWQPVAPMT 
       430        440        450        460        470        480 
TTRSCFAAAV LDGMIYAIGG YGPAHMNSVE RYDPSKDSWE MVASMADKRI HFGVGVMLGF 
       490        500        510        520        530        540 
IFVVGGHNGV SHLSSIERYD PHQNQWTVCR PMKEPRTGVG AAVIDNYLYV VGGHSGSSYL 
       550        560        570    
NTVQKYDPIS DTWLDSAGMI YCRCNFGLTA L

Isoforms

- Isoform 2 of Kelch-like protein 28

Sequence View

        10         20         30         40         50         60 
MDHTSPTYML ANLTHLHSEQ LLQGLNLLRQ HHELCDIILR VGDVKIHAHK VVLASVSPYF 
        70         80         90        100        110        120 
KAMFTGNLSE KENSEVEFQC IDETALQAIV EYAYTGTVFI SQDTVESLLP AANLLQIKLV 
       130        140        150        160        170        180 
LKECCAFLES QLDPGNCIGI SRFAETYGCR DLYLAATKYI CQNFEAVCQT EEFFELTHAD 
       190        200        210        220        230        240 
LDEIVSNDCL NVATEETVFY ALESWIKYDV QERQKYLAQL LNSVRLPLLS VKFLTRLYEA 
       250        260        270        280        290        300 
NHLIRDDRTC KHLLNEALKY HFMPEHRLSH QTVLMTRPRC APKVLCAVGG KSGLFACLDS 
       310        320        330        340        350        360 
VEMYFPQNDS WIGLAPLNIP RYEFGICVLD QKVYVIGGIA TNVRPGVTIR KHENSVECWN 
       370        380        390        400        410        420 
PDTNTWTSLE RMNESRSTLG VVVLAGELYA LGGYDGQSYL QSVEKYIPKI RKWQPVAPMT 
       430        440        450        460        470        480 
TTRSCFAAAV LDGMIYAIGG YGPAHMNSVE RYDPSKDSWE MVASMADKRI HFGVGVMLGF 
       490        500        510        520        530        540 
IFVVGGHNGV SHLSSIERYD PHQNQWTVCR PMKEPRTGVG AAVIDNYLYV VGGHSGSSYL 
       550        560        570    
NTVQKYDPIS DTWLDSAGMI YCRCNFGLTA L



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

1 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9NXS3-1-unknown MDHTSP... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9NXS3-1-unknown MDHTSP... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt79108

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...ACLDSV 300 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt74726
    ...GLTAL 571 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)