Q9NZB8: Molybdenum cofactor biosynthesis protein 1

General Information

Protein names	- Molybdenum cofactor biosynthesis protein 1 - Cell migration-inducing gene 11 protein - Molybdenum cofactor synthesis-step 1 protein A-B - GTP 3',8-cyclase {ECO:0000305} - 4.1.99.22 {ECO:0000250\|UniProtKB:P69848} - Molybdenum cofactor biosynthesis protein A - Cyclic pyranopterin monophosphate synthase {ECO:0000305} - 4.6.1.17 {ECO:0000269\|PubMed:23627491} - Molybdenum cofactor biosynthesis protein C
Gene names	MOCS1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9NZB8

6 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform MOCS1A of Molybdenum cofactor biosynthesis protein 1 - Isoform 2 of Molybdenum cofactor biosynthesis protein 1 - Isoform 3 of Molybdenum cofactor biosynthesis protein 1 - Isoform 4 of Molybdenum cofactor biosynthesis protein 1 - Isoform 6 of Molybdenum cofactor biosynthesis protein 1 - Isoform 7 of Molybdenum cofactor biosynthesis protein 1 - Isoform 8 of Molybdenum cofactor biosynthesis protein 1

Sequence View

        10         20         30         40         50         60
MAARPLSRML RRLLRSSARS CSSGAPVTQP CPGESARAAS EEVSRRRQFL REHAAPFSAF
        70         80         90        100        110        120
LTDSFGRQHS YLRISLTEKC NLRCQYCMPE EGVPLTPKAN LLTTEEILTL ARLFVKEGID
       130        140        150        160        170        180
KIRLTGGEPL IRPDVVDIVA QLQRLEGLRT IGVTTNGINL ARLLPQLQKA GLSAINISLD
       190        200        210        220        230        240
TLVPAKFEFI VRRKGFHKVM EGIHKAIELG YNPVKVNCVV MRGLNEDELL DFAALTEGLP
       250        260        270        280        290        300
LDVRFIEYMP FDGNKWNFKK MVSYKEMLDT VRQQWPELEK VPEEESSTAK AFKIPGFQGQ
       310        320        330        340        350        360
ISFITSMSEH FCGTCNRLRI TADGNLKVCL FGNSEVSLRD HLRAGASEQE LLRIIGAAVG
       370        380        390        400        410        420
RKKRQHAGMF SISQMKNRPM ILIELFLMFP NSPPANPSIF SWDPLHVQGL RPRMSFSSQV
       430        440        450        460        470        480
ATLWKGCRVP QTPPLAQQRL GSGSFQRHYT SRADSDANSK CLSPGSWASA APSGPQLTSE
       490        500        510        520        530        540
QLTHVDSEGR AAMVDVGRKP DTERVAVASA VVLLGPVAFK LVQQNQLKKG DALVVAQLAG
       550        560        570        580        590        600
VQAAKVTSQL IPLCHHVALS HIQVQLELDS TRHAVKIQAS CRARGPTGVE MEALTSAAVA
       610        620        630
ALTLYDMCKA VSRDIVLEEI KLISKTGGQR GDFHRA         10         20         30         40         50         60
MAARPLSRML RRLLRSSARS CSSGAPVTQP CPGESARAAS EEVSRRRQFL REHAAPFSAF
        70         80         90        100        110        120
LTDSFGRQHS YLRISLTEKC NLRCQYCMPE EGVPLTPKAN LLTTEEILTL ARLFVKEGID
       130        140        150        160        170        180
KIRLTGGEPL IRPDVVDIVA QLQRLEGLRT IGVTTNGINL ARLLPQLQKA GLSAINISLD
       190        200        210        220        230        240
TLVPAKFEFI VRRKGFHKVM EGIHKAIELG YNPVKVNCVV MRGLNEDELL DFAALTEGLP
       250        260        270        280        290        300
LDVRFIEYMP FDGNKWNFKK MVSYKEMLDT VRQQWPELEK VPEEESSTAK AFKIPGFQGQ
       310        320        330        340        350        360
ISFITSMSEH FCGTCNRLRI TADGNLKVCL FGNSEVSLRD HLRAGASEQE LLRIIGAAVG
       370        380        390        400        410        420
RKKRQHAGMF SISQMKNRPM ILIELFLMFP NSPPANPSIF SWDPLHVQGL RPRMSFSSQV
       430        440        450        460        470        480
ATLWKGCRVP QTPPLAQQRL GSGSFQRHYT SRADSDANSK CLSPGSWASA APSGPQLTSE
       490        500        510        520        530        540
QLTHVDSEGR AAMVDVGRKP DTERVAVASA VVLLGPVAFK LVQQNQLKKG DALVVAQLAG
       550        560        570        580        590        600
VQAAKVTSQL IPLCHHVALS HIQVQLELDS TRHAVKIQAS CRARGPTGVE MEALTSAAVA
       610        620        630
ALTLYDMCKA VSRDIVLEEI KLISKTGGQR GDFHRA         10         20         30         40         50         60
MAARPLSRML RRLLRSSARS CSSGAPVTQP CPGESARAAS EEVSRRRQFL REHAAPFSAF
        70         80         90        100        110        120
LTDSFGRQHS YLRISLTEKC NLRCQYCMPE EGVPLTPKAN LLTTEEILTL ARLFVKEGID
       130        140        150        160        170        180
KIRLTGGEPL IRPDVVDIVA QLQRLEGLRT IGVTTNGINL ARLLPQLQKA GLSAINISLD
       190        200        210        220        230        240
TLVPAKFEFI VRRKGFHKVM EGIHKAIELG YNPVKVNCVV MRGLNEDELL DFAALTEGLP
       250        260        270        280        290        300
LDVRFIEYMP FDGNKWNFKK MVSYKEMLDT VRQQWPELEK VPEEESSTAK AFKIPGFQGQ
       310        320        330        340        350        360
ISFITSMSEH FCGTCNRLRI TADGNLKVCL FGNSEVSLRD HLRAGASEQE LLRIIGAAVG
       370        380        390        400        410        420
RKKRQHAGMF SISQMKNRPM ILIELFLMFP NSPPANPSIF SWDPLHVQGL RPRMSFSSQV
       430        440        450        460        470        480
ATLWKGCRVP QTPPLAQQRL GSGSFQRHYT SRADSDANSK CLSPGSWASA APSGPQLTSE
       490        500        510        520        530        540
QLTHVDSEGR AAMVDVGRKP DTERVAVASA VVLLGPVAFK LVQQNQLKKG DALVVAQLAG
       550        560        570        580        590        600
VQAAKVTSQL IPLCHHVALS HIQVQLELDS TRHAVKIQAS CRARGPTGVE MEALTSAAVA
       610        620        630
ALTLYDMCKA VSRDIVLEEI KLISKTGGQR GDFHRA         10         20         30         40         50         60
MAARPLSRML RRLLRSSARS CSSGAPVTQP CPGESARAAS EEVSRRRQFL REHAAPFSAF
        70         80         90        100        110        120
LTDSFGRQHS YLRISLTEKC NLRCQYCMPE EGVPLTPKAN LLTTEEILTL ARLFVKEGID
       130        140        150        160        170        180
KIRLTGGEPL IRPDVVDIVA QLQRLEGLRT IGVTTNGINL ARLLPQLQKA GLSAINISLD
       190        200        210        220        230        240
TLVPAKFEFI VRRKGFHKVM EGIHKAIELG YNPVKVNCVV MRGLNEDELL DFAALTEGLP
       250        260        270        280        290        300
LDVRFIEYMP FDGNKWNFKK MVSYKEMLDT VRQQWPELEK VPEEESSTAK AFKIPGFQGQ
       310        320        330        340        350        360
ISFITSMSEH FCGTCNRLRI TADGNLKVCL FGNSEVSLRD HLRAGASEQE LLRIIGAAVG
       370        380        390        400        410        420
RKKRQHAGMF SISQMKNRPM ILIELFLMFP NSPPANPSIF SWDPLHVQGL RPRMSFSSQV
       430        440        450        460        470        480
ATLWKGCRVP QTPPLAQQRL GSGSFQRHYT SRADSDANSK CLSPGSWASA APSGPQLTSE
       490        500        510        520        530        540
QLTHVDSEGR AAMVDVGRKP DTERVAVASA VVLLGPVAFK LVQQNQLKKG DALVVAQLAG
       550        560        570        580        590        600
VQAAKVTSQL IPLCHHVALS HIQVQLELDS TRHAVKIQAS CRARGPTGVE MEALTSAAVA
       610        620        630
ALTLYDMCKA VSRDIVLEEI KLISKTGGQR GDFHRA         10         20         30         40         50         60
MAARPLSRML RRLLRSSARS CSSGAPVTQP CPGESARAAS EEVSRRRQFL REHAAPFSAF
        70         80         90        100        110        120
LTDSFGRQHS YLRISLTEKC NLRCQYCMPE EGVPLTPKAN LLTTEEILTL ARLFVKEGID
       130        140        150        160        170        180
KIRLTGGEPL IRPDVVDIVA QLQRLEGLRT IGVTTNGINL ARLLPQLQKA GLSAINISLD
       190        200        210        220        230        240
TLVPAKFEFI VRRKGFHKVM EGIHKAIELG YNPVKVNCVV MRGLNEDELL DFAALTEGLP
       250        260        270        280        290        300
LDVRFIEYMP FDGNKWNFKK MVSYKEMLDT VRQQWPELEK VPEEESSTAK AFKIPGFQGQ
       310        320        330        340        350        360
ISFITSMSEH FCGTCNRLRI TADGNLKVCL FGNSEVSLRD HLRAGASEQE LLRIIGAAVG
       370        380        390        400        410        420
RKKRQHAGMF SISQMKNRPM ILIELFLMFP NSPPANPSIF SWDPLHVQGL RPRMSFSSQV
       430        440        450        460        470        480
ATLWKGCRVP QTPPLAQQRL GSGSFQRHYT SRADSDANSK CLSPGSWASA APSGPQLTSE
       490        500        510        520        530        540
QLTHVDSEGR AAMVDVGRKP DTERVAVASA VVLLGPVAFK LVQQNQLKKG DALVVAQLAG
       550        560        570        580        590        600
VQAAKVTSQL IPLCHHVALS HIQVQLELDS TRHAVKIQAS CRARGPTGVE MEALTSAAVA
       610        620        630
ALTLYDMCKA VSRDIVLEEI KLISKTGGQR GDFHRA         10         20         30         40         50         60
MAARPLSRML RRLLRSSARS CSSGAPVTQP CPGESARAAS EEVSRRRQFL REHAAPFSAF
        70         80         90        100        110        120
LTDSFGRQHS YLRISLTEKC NLRCQYCMPE EGVPLTPKAN LLTTEEILTL ARLFVKEGID
       130        140        150        160        170        180
KIRLTGGEPL IRPDVVDIVA QLQRLEGLRT IGVTTNGINL ARLLPQLQKA GLSAINISLD
       190        200        210        220        230        240
TLVPAKFEFI VRRKGFHKVM EGIHKAIELG YNPVKVNCVV MRGLNEDELL DFAALTEGLP
       250        260        270        280        290        300
LDVRFIEYMP FDGNKWNFKK MVSYKEMLDT VRQQWPELEK VPEEESSTAK AFKIPGFQGQ
       310        320        330        340        350        360
ISFITSMSEH FCGTCNRLRI TADGNLKVCL FGNSEVSLRD HLRAGASEQE LLRIIGAAVG
       370        380        390        400        410        420
RKKRQHAGMF SISQMKNRPM ILIELFLMFP NSPPANPSIF SWDPLHVQGL RPRMSFSSQV
       430        440        450        460        470        480
ATLWKGCRVP QTPPLAQQRL GSGSFQRHYT SRADSDANSK CLSPGSWASA APSGPQLTSE
       490        500        510        520        530        540
QLTHVDSEGR AAMVDVGRKP DTERVAVASA VVLLGPVAFK LVQQNQLKKG DALVVAQLAG
       550        560        570        580        590        600
VQAAKVTSQL IPLCHHVALS HIQVQLELDS TRHAVKIQAS CRARGPTGVE MEALTSAAVA
       610        620        630
ALTLYDMCKA VSRDIVLEEI KLISKTGGQR GDFHRA         10         20         30         40         50         60
MAARPLSRML RRLLRSSARS CSSGAPVTQP CPGESARAAS EEVSRRRQFL REHAAPFSAF
        70         80         90        100        110        120
LTDSFGRQHS YLRISLTEKC NLRCQYCMPE EGVPLTPKAN LLTTEEILTL ARLFVKEGID
       130        140        150        160        170        180
KIRLTGGEPL IRPDVVDIVA QLQRLEGLRT IGVTTNGINL ARLLPQLQKA GLSAINISLD
       190        200        210        220        230        240
TLVPAKFEFI VRRKGFHKVM EGIHKAIELG YNPVKVNCVV MRGLNEDELL DFAALTEGLP
       250        260        270        280        290        300
LDVRFIEYMP FDGNKWNFKK MVSYKEMLDT VRQQWPELEK VPEEESSTAK AFKIPGFQGQ
       310        320        330        340        350        360
ISFITSMSEH FCGTCNRLRI TADGNLKVCL FGNSEVSLRD HLRAGASEQE LLRIIGAAVG
       370        380        390        400        410        420
RKKRQHAGMF SISQMKNRPM ILIELFLMFP NSPPANPSIF SWDPLHVQGL RPRMSFSSQV
       430        440        450        460        470        480
ATLWKGCRVP QTPPLAQQRL GSGSFQRHYT SRADSDANSK CLSPGSWASA APSGPQLTSE
       490        500        510        520        530        540
QLTHVDSEGR AAMVDVGRKP DTERVAVASA VVLLGPVAFK LVQQNQLKKG DALVVAQLAG
       550        560        570        580        590        600
VQAAKVTSQL IPLCHHVALS HIQVQLELDS TRHAVKIQAS CRARGPTGVE MEALTSAAVA
       610        620        630
ALTLYDMCKA VSRDIVLEEI KLISKTGGQR GDFHRA

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

6 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9NZB8-1-unknown	MAARPL...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9NZB8-1-unknown	MAARPL...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt81344
Q9NZB8-1-unknown	MAARPL...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt81348
Q9NZB8-88-unknown	MPEEGV...	88	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt81347
Q9NZB8-88-unknown	MPEEGV...	88	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt81349
Q9NZB8-88-unknown	MPEEGV...	88	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt106799
Q9NZB8-88-unknown	MPEEGV...	88	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt106797
Q9NZB8-88-unknown	MPEEGV...	88	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt106798
Q9NZB8-88-unknown	MPEEGV...	88	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt106800
Q9NZB8-88-unknown	MPEEGV...	88	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt106801
Q9NZB8-88-unknown	MPEEGV...	88	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9NZB8-469-unknown	SAAPSG...	469		unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q9NZB8-469-unknown	SAAPSG...	469	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt161821
Q9NZB8-469-unknown	SAAPSG...	469	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt161822
Q9NZB8-469-unknown	SAAPSG...	469	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt161820
Q9NZB8-469-	SAAPSG...	469		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
Q9NZB8-470-	AAPSGP...	470		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
Q9NZB8-470-	AAPSGP...	470		Subtiligase Based Positive Selection		Wells	apopotic_Jurkat_FasL	23264352
Q9NZB8-470-	AAPSGP...	470		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
Q9NZB8-470-unknown	AAPSGP...	470		unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q9NZB8-470-unknown	AAPSGP...	470	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt161817
Q9NZB8-470-unknown	AAPSGP...	470	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt161818
Q9NZB8-470-unknown	AAPSGP...	470	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt161816

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...DFHRA	636	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...DFHRA	636	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt76967
...DFHRA	636	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt76966
...DFHRA	636	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt76968

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)