TopFIND 4.0

Q9NZK5: Adenosine deaminase 2 {ECO:0000312|HGNC:HGNC:1839}

General Information

Protein names
- Adenosine deaminase 2 {ECO:0000312|HGNC:HGNC:1839}
- 3.5.4.4 {ECO:0000269|PubMed:15926889, ECO:0000269|PubMed:20453107}
- Cat eye syndrome critical region protein 1
Gene names CECR1
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q9NZK5

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MLVDGPSERP ALCFLLLAVA MSFFGSALSI DETRAHLLLK EKMMRLGGRL VLNTKEELAN 
        70         80         90        100        110        120 
ERLMTLKIAE MKEAMRTLIF PPSMHFFQAK HLIERSQVFN ILRMMPKGAA LHLHDIGIVT 
       130        140        150        160        170        180 
MDWLVRNVTY RPHCHICFTP RGIMQFRFAH PTPRPSEKCS KWILLEDYRK RVQNVTEFDD 
       190        200        210        220        230        240 
SLLRNFTLVT QHPEVIYTNQ NVVWSKFETI FFTISGLIHY APVFRDYVFR SMQEFYEDNV 
       250        260        270        280        290        300 
LYMEIRARLL PVYELSGEHH DEEWSVKTYQ EVAQKFVETH PEFIGIKIIY SDHRSKDVAV 
       310        320        330        340        350        360 
IAESIRMAMG LRIKFPTVVA GFDLVGHEDT GHSLHDYKEA LMIPAKDGVK LPYFFHAGET 
       370        380        390        400        410        420 
DWQGTSIDRN ILDALMLNTT RIGHGFALSK HPAVRTYSWK KDIPIEVCPI SNQVLKLVSD 
       430        440        450        460        470        480 
LRNHPVATLM ATGHPMVISS DDPAMFGAKG LSYDFYEVFM GIGGMKADLR TLKQLAMNSI 
       490        500        510    
KYSTLLESEK NTFMEIWKKR WDKFIADVAT K

Isoforms

- Isoform 2 of Adenosine deaminase CECR1 - Isoform 2 of Adenosine deaminase 2

Sequence View

        10         20         30         40         50         60 
MLVDGPSERP ALCFLLLAVA MSFFGSALSI DETRAHLLLK EKMMRLGGRL VLNTKEELAN 
        70         80         90        100        110        120 
ERLMTLKIAE MKEAMRTLIF PPSMHFFQAK HLIERSQVFN ILRMMPKGAA LHLHDIGIVT 
       130        140        150        160        170        180 
MDWLVRNVTY RPHCHICFTP RGIMQFRFAH PTPRPSEKCS KWILLEDYRK RVQNVTEFDD 
       190        200        210        220        230        240 
SLLRNFTLVT QHPEVIYTNQ NVVWSKFETI FFTISGLIHY APVFRDYVFR SMQEFYEDNV 
       250        260        270        280        290        300 
LYMEIRARLL PVYELSGEHH DEEWSVKTYQ EVAQKFVETH PEFIGIKIIY SDHRSKDVAV 
       310        320        330        340        350        360 
IAESIRMAMG LRIKFPTVVA GFDLVGHEDT GHSLHDYKEA LMIPAKDGVK LPYFFHAGET 
       370        380        390        400        410        420 
DWQGTSIDRN ILDALMLNTT RIGHGFALSK HPAVRTYSWK KDIPIEVCPI SNQVLKLVSD 
       430        440        450        460        470        480 
LRNHPVATLM ATGHPMVISS DDPAMFGAKG LSYDFYEVFM GIGGMKADLR TLKQLAMNSI 
       490        500        510    
KYSTLLESEK NTFMEIWKKR WDKFIADVAT K         10         20         30         40         50         60 
MLVDGPSERP ALCFLLLAVA MSFFGSALSI DETRAHLLLK EKMMRLGGRL VLNTKEELAN 
        70         80         90        100        110        120 
ERLMTLKIAE MKEAMRTLIF PPSMHFFQAK HLIERSQVFN ILRMMPKGAA LHLHDIGIVT 
       130        140        150        160        170        180 
MDWLVRNVTY RPHCHICFTP RGIMQFRFAH PTPRPSEKCS KWILLEDYRK RVQNVTEFDD 
       190        200        210        220        230        240 
SLLRNFTLVT QHPEVIYTNQ NVVWSKFETI FFTISGLIHY APVFRDYVFR SMQEFYEDNV 
       250        260        270        280        290        300 
LYMEIRARLL PVYELSGEHH DEEWSVKTYQ EVAQKFVETH PEFIGIKIIY SDHRSKDVAV 
       310        320        330        340        350        360 
IAESIRMAMG LRIKFPTVVA GFDLVGHEDT GHSLHDYKEA LMIPAKDGVK LPYFFHAGET 
       370        380        390        400        410        420 
DWQGTSIDRN ILDALMLNTT RIGHGFALSK HPAVRTYSWK KDIPIEVCPI SNQVLKLVSD 
       430        440        450        460        470        480 
LRNHPVATLM ATGHPMVISS DDPAMFGAKG LSYDFYEVFM GIGGMKADLR TLKQLAMNSI 
       490        500        510    
KYSTLLESEK NTFMEIWKKR WDKFIADVAT K



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9NZK5-30-unknown IDETRA... 30 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...DVATK 511 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...DVATK 511 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt65855

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)