Q9NZM6: Polycystic kidney disease 2-like 2 protein

General Information

Protein names	- Polycystic kidney disease 2-like 2 protein - Polycystin-2L2 - Polycystin-L2
Gene names	PKD2L2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9NZM6

1 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAEASRWHRG GASKHKLHYR KEVEITTTLQ ELLLYFIFLI NLCILTFGMV NPHMYYLNKV
        70         80         90        100        110        120
MSSLFLDTSV PGEERTNFKS IRSITDFWKF MEGPLLEGLY WDSWYNNQQL YNLKNSSRIY
       130        140        150        160        170        180
YENILLGVPR VRQLKVRNNT CKVYSSFQSL MSECYGKYTS ANEDLSNFGL QINTEWRYST
       190        200        210        220        230        240
SNTNSPWHWG FLGVYRNGGY IFTLSKSKSE TKNKFIDLRL NSWITRGTRV IFIDFSLYNA
       250        260        270        280        290        300
NVNLFCIIRL VAEFPATGGI LTSWQFYSVK LLRYVSYYDY FIASCEITFC IFLFVFTTQE
       310        320        330        340        350        360
VKKIKEFKSA YFKSIWNWLE LLLLLLCFVA VSFNTYYNVQ IFLLLGQLLK STEKYSDFYF
       370        380        390        400        410        420
LACWHIYYNN IIAITIFFAW IKIFKFISFN KTMSQLSSTL SRCVKDIVGF AIMFFIIFFA
       430        440        450        460        470        480
YAQLGFLVFG SQVDDFSTFQ NSIFAQFRIV LGDFNFAGIQ QANPILGPIY FITFIFFVFF
       490        500        510        520        530        540
VLLNMFLAII NDTYSEVKAD YSIGRRLDFE LGKMIKQSYK NVLEKFRLKK AQKDEDKKTK
       550        560        570        580        590        600
GSGDLAEQAR REGFDENEIQ NAEQMKKWKE RLEKKYYSME IQDDYQPVTQ EEFRELFLYA
       610        620
VELEKELHYI NLKLNQVVRK VSAL

Isoforms

- Isoform 2 of Polycystic kidney disease 2-like 2 protein - Isoform 3 of Polycystic kidney disease 2-like 2 protein - Isoform 4 of Polycystic kidney disease 2-like 2 protein - Isoform 5 of Polycystic kidney disease 2-like 2 protein - Isoform 6 of Polycystic kidney disease 2-like 2 protein - Isoform 7 of Polycystic kidney disease 2-like 2 protein

Sequence View

        10         20         30         40         50         60
MAEASRWHRG GASKHKLHYR KEVEITTTLQ ELLLYFIFLI NLCILTFGMV NPHMYYLNKV
        70         80         90        100        110        120
MSSLFLDTSV PGEERTNFKS IRSITDFWKF MEGPLLEGLY WDSWYNNQQL YNLKNSSRIY
       130        140        150        160        170        180
YENILLGVPR VRQLKVRNNT CKVYSSFQSL MSECYGKYTS ANEDLSNFGL QINTEWRYST
       190        200        210        220        230        240
SNTNSPWHWG FLGVYRNGGY IFTLSKSKSE TKNKFIDLRL NSWITRGTRV IFIDFSLYNA
       250        260        270        280        290        300
NVNLFCIIRL VAEFPATGGI LTSWQFYSVK LLRYVSYYDY FIASCEITFC IFLFVFTTQE
       310        320        330        340        350        360
VKKIKEFKSA YFKSIWNWLE LLLLLLCFVA VSFNTYYNVQ IFLLLGQLLK STEKYSDFYF
       370        380        390        400        410        420
LACWHIYYNN IIAITIFFAW IKIFKFISFN KTMSQLSSTL SRCVKDIVGF AIMFFIIFFA
       430        440        450        460        470        480
YAQLGFLVFG SQVDDFSTFQ NSIFAQFRIV LGDFNFAGIQ QANPILGPIY FITFIFFVFF
       490        500        510        520        530        540
VLLNMFLAII NDTYSEVKAD YSIGRRLDFE LGKMIKQSYK NVLEKFRLKK AQKDEDKKTK
       550        560        570        580        590        600
GSGDLAEQAR REGFDENEIQ NAEQMKKWKE RLEKKYYSME IQDDYQPVTQ EEFRELFLYA
       610        620
VELEKELHYI NLKLNQVVRK VSAL         10         20         30         40         50         60
MAEASRWHRG GASKHKLHYR KEVEITTTLQ ELLLYFIFLI NLCILTFGMV NPHMYYLNKV
        70         80         90        100        110        120
MSSLFLDTSV PGEERTNFKS IRSITDFWKF MEGPLLEGLY WDSWYNNQQL YNLKNSSRIY
       130        140        150        160        170        180
YENILLGVPR VRQLKVRNNT CKVYSSFQSL MSECYGKYTS ANEDLSNFGL QINTEWRYST
       190        200        210        220        230        240
SNTNSPWHWG FLGVYRNGGY IFTLSKSKSE TKNKFIDLRL NSWITRGTRV IFIDFSLYNA
       250        260        270        280        290        300
NVNLFCIIRL VAEFPATGGI LTSWQFYSVK LLRYVSYYDY FIASCEITFC IFLFVFTTQE
       310        320        330        340        350        360
VKKIKEFKSA YFKSIWNWLE LLLLLLCFVA VSFNTYYNVQ IFLLLGQLLK STEKYSDFYF
       370        380        390        400        410        420
LACWHIYYNN IIAITIFFAW IKIFKFISFN KTMSQLSSTL SRCVKDIVGF AIMFFIIFFA
       430        440        450        460        470        480
YAQLGFLVFG SQVDDFSTFQ NSIFAQFRIV LGDFNFAGIQ QANPILGPIY FITFIFFVFF
       490        500        510        520        530        540
VLLNMFLAII NDTYSEVKAD YSIGRRLDFE LGKMIKQSYK NVLEKFRLKK AQKDEDKKTK
       550        560        570        580        590        600
GSGDLAEQAR REGFDENEIQ NAEQMKKWKE RLEKKYYSME IQDDYQPVTQ EEFRELFLYA
       610        620
VELEKELHYI NLKLNQVVRK VSAL         10         20         30         40         50         60
MAEASRWHRG GASKHKLHYR KEVEITTTLQ ELLLYFIFLI NLCILTFGMV NPHMYYLNKV
        70         80         90        100        110        120
MSSLFLDTSV PGEERTNFKS IRSITDFWKF MEGPLLEGLY WDSWYNNQQL YNLKNSSRIY
       130        140        150        160        170        180
YENILLGVPR VRQLKVRNNT CKVYSSFQSL MSECYGKYTS ANEDLSNFGL QINTEWRYST
       190        200        210        220        230        240
SNTNSPWHWG FLGVYRNGGY IFTLSKSKSE TKNKFIDLRL NSWITRGTRV IFIDFSLYNA
       250        260        270        280        290        300
NVNLFCIIRL VAEFPATGGI LTSWQFYSVK LLRYVSYYDY FIASCEITFC IFLFVFTTQE
       310        320        330        340        350        360
VKKIKEFKSA YFKSIWNWLE LLLLLLCFVA VSFNTYYNVQ IFLLLGQLLK STEKYSDFYF
       370        380        390        400        410        420
LACWHIYYNN IIAITIFFAW IKIFKFISFN KTMSQLSSTL SRCVKDIVGF AIMFFIIFFA
       430        440        450        460        470        480
YAQLGFLVFG SQVDDFSTFQ NSIFAQFRIV LGDFNFAGIQ QANPILGPIY FITFIFFVFF
       490        500        510        520        530        540
VLLNMFLAII NDTYSEVKAD YSIGRRLDFE LGKMIKQSYK NVLEKFRLKK AQKDEDKKTK
       550        560        570        580        590        600
GSGDLAEQAR REGFDENEIQ NAEQMKKWKE RLEKKYYSME IQDDYQPVTQ EEFRELFLYA
       610        620
VELEKELHYI NLKLNQVVRK VSAL         10         20         30         40         50         60
MAEASRWHRG GASKHKLHYR KEVEITTTLQ ELLLYFIFLI NLCILTFGMV NPHMYYLNKV
        70         80         90        100        110        120
MSSLFLDTSV PGEERTNFKS IRSITDFWKF MEGPLLEGLY WDSWYNNQQL YNLKNSSRIY
       130        140        150        160        170        180
YENILLGVPR VRQLKVRNNT CKVYSSFQSL MSECYGKYTS ANEDLSNFGL QINTEWRYST
       190        200        210        220        230        240
SNTNSPWHWG FLGVYRNGGY IFTLSKSKSE TKNKFIDLRL NSWITRGTRV IFIDFSLYNA
       250        260        270        280        290        300
NVNLFCIIRL VAEFPATGGI LTSWQFYSVK LLRYVSYYDY FIASCEITFC IFLFVFTTQE
       310        320        330        340        350        360
VKKIKEFKSA YFKSIWNWLE LLLLLLCFVA VSFNTYYNVQ IFLLLGQLLK STEKYSDFYF
       370        380        390        400        410        420
LACWHIYYNN IIAITIFFAW IKIFKFISFN KTMSQLSSTL SRCVKDIVGF AIMFFIIFFA
       430        440        450        460        470        480
YAQLGFLVFG SQVDDFSTFQ NSIFAQFRIV LGDFNFAGIQ QANPILGPIY FITFIFFVFF
       490        500        510        520        530        540
VLLNMFLAII NDTYSEVKAD YSIGRRLDFE LGKMIKQSYK NVLEKFRLKK AQKDEDKKTK
       550        560        570        580        590        600
GSGDLAEQAR REGFDENEIQ NAEQMKKWKE RLEKKYYSME IQDDYQPVTQ EEFRELFLYA
       610        620
VELEKELHYI NLKLNQVVRK VSAL         10         20         30         40         50         60
MAEASRWHRG GASKHKLHYR KEVEITTTLQ ELLLYFIFLI NLCILTFGMV NPHMYYLNKV
        70         80         90        100        110        120
MSSLFLDTSV PGEERTNFKS IRSITDFWKF MEGPLLEGLY WDSWYNNQQL YNLKNSSRIY
       130        140        150        160        170        180
YENILLGVPR VRQLKVRNNT CKVYSSFQSL MSECYGKYTS ANEDLSNFGL QINTEWRYST
       190        200        210        220        230        240
SNTNSPWHWG FLGVYRNGGY IFTLSKSKSE TKNKFIDLRL NSWITRGTRV IFIDFSLYNA
       250        260        270        280        290        300
NVNLFCIIRL VAEFPATGGI LTSWQFYSVK LLRYVSYYDY FIASCEITFC IFLFVFTTQE
       310        320        330        340        350        360
VKKIKEFKSA YFKSIWNWLE LLLLLLCFVA VSFNTYYNVQ IFLLLGQLLK STEKYSDFYF
       370        380        390        400        410        420
LACWHIYYNN IIAITIFFAW IKIFKFISFN KTMSQLSSTL SRCVKDIVGF AIMFFIIFFA
       430        440        450        460        470        480
YAQLGFLVFG SQVDDFSTFQ NSIFAQFRIV LGDFNFAGIQ QANPILGPIY FITFIFFVFF
       490        500        510        520        530        540
VLLNMFLAII NDTYSEVKAD YSIGRRLDFE LGKMIKQSYK NVLEKFRLKK AQKDEDKKTK
       550        560        570        580        590        600
GSGDLAEQAR REGFDENEIQ NAEQMKKWKE RLEKKYYSME IQDDYQPVTQ EEFRELFLYA
       610        620
VELEKELHYI NLKLNQVVRK VSAL         10         20         30         40         50         60
MAEASRWHRG GASKHKLHYR KEVEITTTLQ ELLLYFIFLI NLCILTFGMV NPHMYYLNKV
        70         80         90        100        110        120
MSSLFLDTSV PGEERTNFKS IRSITDFWKF MEGPLLEGLY WDSWYNNQQL YNLKNSSRIY
       130        140        150        160        170        180
YENILLGVPR VRQLKVRNNT CKVYSSFQSL MSECYGKYTS ANEDLSNFGL QINTEWRYST
       190        200        210        220        230        240
SNTNSPWHWG FLGVYRNGGY IFTLSKSKSE TKNKFIDLRL NSWITRGTRV IFIDFSLYNA
       250        260        270        280        290        300
NVNLFCIIRL VAEFPATGGI LTSWQFYSVK LLRYVSYYDY FIASCEITFC IFLFVFTTQE
       310        320        330        340        350        360
VKKIKEFKSA YFKSIWNWLE LLLLLLCFVA VSFNTYYNVQ IFLLLGQLLK STEKYSDFYF
       370        380        390        400        410        420
LACWHIYYNN IIAITIFFAW IKIFKFISFN KTMSQLSSTL SRCVKDIVGF AIMFFIIFFA
       430        440        450        460        470        480
YAQLGFLVFG SQVDDFSTFQ NSIFAQFRIV LGDFNFAGIQ QANPILGPIY FITFIFFVFF
       490        500        510        520        530        540
VLLNMFLAII NDTYSEVKAD YSIGRRLDFE LGKMIKQSYK NVLEKFRLKK AQKDEDKKTK
       550        560        570        580        590        600
GSGDLAEQAR REGFDENEIQ NAEQMKKWKE RLEKKYYSME IQDDYQPVTQ EEFRELFLYA
       610        620
VELEKELHYI NLKLNQVVRK VSAL

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q9NZM6-1-unknown	MAEASR...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q9NZM6-1-unknown	MAEASR...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt85312
Q9NZM6-1-unknown	MAEASR...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt85314
Q9NZM6-1-unknown	MAEASR...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt85315
Q9NZM6-1-unknown	MAEASR...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt85316

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...KVSAL	624	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...KVSAL	624	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt80933
...KVSAL	624	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt80929
...KVSAL	624	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt80934

TopFIND

Q9NZM6: Polycystic kidney disease 2-like 2 protein

General Information

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates