TopFIND 4.0

Q9P0I2: ER membrane protein complex subunit 3

General Information

Protein names
- ER membrane protein complex subunit 3
- Transmembrane protein 111
Gene names EMC3
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q9P0I2

2

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAGPELLLDS NIRLWVVLPI VIITFFVGMI RHYVSILLQS DKKLTQEQVS DSQVLIRSRV 
        70         80         90        100        110        120 
LRENGKYIPK QSFLTRKYYF NNPEDGFFKK TKRKVVPPSP MTDPTMLTDM MKGNVTNVLP 
       130        140        150        160        170        180 
MILIGGWINM TFSGFVTTKV PFPLTLRFKP MLQQGIELLT LDASWVSSAS WYFLNVFGLR 
       190        200        210        220        230        240 
SIYSLILGQD NAADQSRMMQ EQMTGAAMAM PADTNKAFKT EWEALELTDH QWALDDVEEE 
       250        260    
LMAKDLHFEG MFKKELQTSI F

Isoforms

- Isoform 2 of ER membrane protein complex subunit 3

Sequence View

        10         20         30         40         50         60 
MAGPELLLDS NIRLWVVLPI VIITFFVGMI RHYVSILLQS DKKLTQEQVS DSQVLIRSRV 
        70         80         90        100        110        120 
LRENGKYIPK QSFLTRKYYF NNPEDGFFKK TKRKVVPPSP MTDPTMLTDM MKGNVTNVLP 
       130        140        150        160        170        180 
MILIGGWINM TFSGFVTTKV PFPLTLRFKP MLQQGIELLT LDASWVSSAS WYFLNVFGLR 
       190        200        210        220        230        240 
SIYSLILGQD NAADQSRMMQ EQMTGAAMAM PADTNKAFKT EWEALELTDH QWALDDVEEE 
       250        260    
LMAKDLHFEG MFKKELQTSI F



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Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9P0I2-1-unknown MAGPEL... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt73883
    Q9P0I2-2-unknown AGPELL... 2 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9P0I2-2-unknown AGPELL... 2 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt110018

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...NKAFKT 219 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt69501
    ...QTSIF 261 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)