TopFIND 4.0

Q9P0N8: E3 ubiquitin-protein ligase MARCH2

General Information

Protein names
- E3 ubiquitin-protein ligase MARCH2
- 2.3.2.27
- Membrane-associated RING finger protein 2
- Membrane-associated RING-CH protein II
- MARCH-II
- RING finger protein 172
- RING-type E3 ubiquitin transferase MARCH2 {ECO:0000305}
Gene names MARCH2
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q9P0N8

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MTTGDCCHLP GSLCDCSGSP AFSKVVEATG LGPPQYVAQV TSRDGRLLST VIRALDTPSD 
        70         80         90        100        110        120 
GPFCRICHEG ANGECLLSPC GCTGTLGAVH KSCLEKWLSS SNTSYCELCH TEFAVEKRPR 
       130        140        150        160        170        180 
PLTEWLKDPG PRTEKRTLCC DMVCFLFITP LAAISGWLCL RGAQDHLRLH SQLEAVGLIA 
       190        200        210        220        230        240 
LTIALFTIYV LWTLVSFRYH CQLYSEWRKT NQKVRLKIRE ADSPEGPQHS PLAAGLLKKV 
   
AEETPV

Isoforms

- Isoform 2 of E3 ubiquitin-protein ligase MARCH2

Sequence View

        10         20         30         40         50         60 
MTTGDCCHLP GSLCDCSGSP AFSKVVEATG LGPPQYVAQV TSRDGRLLST VIRALDTPSD 
        70         80         90        100        110        120 
GPFCRICHEG ANGECLLSPC GCTGTLGAVH KSCLEKWLSS SNTSYCELCH TEFAVEKRPR 
       130        140        150        160        170        180 
PLTEWLKDPG PRTEKRTLCC DMVCFLFITP LAAISGWLCL RGAQDHLRLH SQLEAVGLIA 
       190        200        210        220        230        240 
LTIALFTIYV LWTLVSFRYH CQLYSEWRKT NQKVRLKIRE ADSPEGPQHS PLAAGLLKKV 
   
AEETPV



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9P0N8-1-unknown MTTGDC... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9P0N8-1-unknown MTTGDC... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt80414

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...EETPV 246 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...EETPV 246 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt76032

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)